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Back squat and deadlift fatiguing protocols elicit distinct countermovement jump profiles: phase-specific predictors and soreness responses
INTRODUCTION OR BACKGROUND: Residual fatigue following resistance exercise can impair neuromuscular performance. The back squat (BSQ) and deadlift (DL) are key lower-limb exercises but may differ in their fatigue and recovery profiles. Identifying phase-specific markers during the countermovement jump (CMJ) may improve monitoring and guide recovery strategies. →
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Effects of Tai Chi combined with elastic band training on muscle and executive inhibitory function in older adults with sarcopenia: a randomized controlled trial based on fNIRS
CONCLUSIONS: A 12-week Tai Chi combined with elastic band training program improves physical mobility, enhances executive inhibition, and promotes PFC activation in patients with sarcopenia, with superior efficacy compared to elastic band training alone. These findings provide neuroimaging evidence for the synergistic effects of the combined intervention in sarcopenia intervention. →
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Acute Clinical Effects of Dual-Task Resistance Exercise on Muscle Endurance and Pressure Sensitivity in Patients With Carpal Tunnel Syndrome After Surgery
CONCLUSION: In patients recovering from CTR surgery, dual-tasking as a cognitive distraction strategy acutely improved exercise capacity by increasing the number of repetitions to failure. →
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Advice From the Founders of Slack, OpenAI, Stripe, and More.
This is a collection of reflections from founders who have collectively built over $3 trillion in enterprise value. Each quote captures a defining moment: a decision, a near-breaking point, or a belief no one else saw. What follows is what they learned, and what you can apply. Sales today still relies on manual work: stitching… →
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Non-invasive endotyping improves treatment satisfaction and prescribing appropriateness in patients with angina and no obstructive coronary artery disease
CONCLUSIONS: In patients with ANOCA, non-invasive CMR-guided endotyping substantially improves treatment satisfaction and enables more appropriate, mechanism-targeted pharmacotherapy compared with angiography-guided care. →
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A Peer-Led, Nurse-Involved Blended Online and Offline Peer Support Program (PNO2PSP) for Psychosocial Adjustment in Young- to Middle-Aged Patients With Breast Cancer: Cluster Randomized Clinical Trial
CONCLUSIONS: The PNO2PSP effectively improved psychosocial adjustment, social support, and positive coping in young- to middle-aged patients with breast cancer. Its scientifically validated, feasible, and patient-centered design supports its recommendation for wider clinical implementation, with continued training for peer supporters and sustained delivery of peer support. →
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Long-Term Outcomes, Moderators, and Predictors in Online Mindfulness-Based Cognitive Therapy for People With Cancer: Secondary Analysis of a Randomized Controlled Trial
CONCLUSIONS: Group-blended and individual-unguided eMBCTs effectively reduced psychological distress and improved well-being among people with cancer and survivors, with greater benefits for those with fewer psychological resources. However, individuals experiencing higher levels of distress were more likely to discontinue group-blended eMBCT. These findings highlight the importance of considering individual preferences and pragmatic factors in treatment… →
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Podcast: When It Comes to Biases, AI’s Only Human
Just like the humans who train them, generative AI models can skew a certain way. As a leader, it’s important to understand how those biases can creep in. “If you care about innovation, if you care about being someone who can step outside the box and predict what is next in the industry, use AI… →
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Who Should Decide the Outcome for a Clinical Trial? Comparing the Views of Stakeholders on Intervention Benefit Using Multi-Criteria Decision Modelling of Cognitive Remediation
CONCLUSIONS: This study shows how stakeholder values can identify nuances in outcomes depending on the value placed on treatment benefits. Embedding this approach into trial design can strengthen the alignment of outcomes with patient and service priorities and help close the gap between randomized trials and service implementation. →
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Does Attention-Deficit/Hyperactivity Disorder Predominant Presentation Matter? Examining Functional and Symptom Changes After Cognitive Behavioural Therapy
CONCLUSIONS: CBT is highly effective and durable across ADHD presentations and formats. Although the combined presentation exhibited a more pronounced reduction in core symptoms, this differential trajectory represents a promising clinical trend requiring cautious interpretation. While brief formats efficiently address core symptoms, standard programs may better optimize long-term functional recovery. →