Clinical Trials
Category Added in a WPeMatico Campaign
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Unveiling the complexity: predicting long-term CPAP adherence among patients with moderate to severe OSA undergoing ‘Interval’ CPAP Titration study. A prospective randomised study
CONCLUSION: A trial of CPAP before a titration study could improve acceptability, lower the CPAP pressures and improve long-term adherence in patients with moderate to severe OSA.
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Effect of artificial intelligence-assisted personalized feedback on radiographic diagnostic performance of dental students: a controlled study
CONCLUSIONS: ChatGPT-4o based personalized feedback proved to be an effective tool for enhancing diagnostic performance and supporting learning in dental education. The findings suggest that AI-driven individualized educational strategies hold significant potential in the future of dental training.
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Comparative efficacy of 200 mg versus 1200 mg of simethicone with 3 L polyethylene glycol electrolyte solution for afternoon colonoscopy: a randomized controlled trial
CONCLUSION: 200 mg versus 1200 mg of SIM in 3 L PEG-ELS for afternoon colonoscopy demonstrated no statistically significant difference in bowel cleansing quality, ADR and bowel preparation-related adverse events. This evidence supports the clinical feasibility of 200 mg simethicone as an effective alternative for optimizing colonic preparation while maintaining procedural standards.
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Sputum colour charts to guide antibiotic self-treatment of acute exacerbation of chronic obstructive pulmonary disease: the Colour-COPD RCT
CONCLUSION: Under-recruitment precluded definitive conclusions. However, sputum colour is unlikely to be a useful addition to COPD SM in primary care.
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Smart Continence Care for People With Profound Intellectual and Multiple Disabilities Within Dutch Residential Care Facilities: Economic Evaluation Alongside a Cluster Randomized Trial
CONCLUSIONS: The results of this economic evaluation are not conclusive because of the mixed outcomes and a limited timeframe. SCC is ineffective in reducing the number of weekly leakages, but it does reduce the number of weekly IMCs. However, SCC was not effective in reducing time spent on continence care. Findings suggest that SCC is…
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Influence of Cannabidiol Use on Visual Function and Optical Quality: A Randomized Controlled Trial
CONCLUSIONS: This non-psychotropic CBD did not appear to adversely affect vision and seems to be a safe substance in the short term at the concentrations assessed.
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A randomized, double blind, placebo-controlled pilot study to assess the efficacy of erenumab in individuals with temporomandibular disorder
CONCLUSIONS: Erenumab was not efficacious in reducing TMD myalgic pain in this phase II trial of 30 subjects with relatively mild pain.
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Comparison of the efficacy of connective tissue massage and manual lymphatic drainage in patients with migraine: a randomized controlled trial
CONCLUSIONS: These findings suggest that CTM and MLD can help migraine patients, with MLD showing a stronger effect on pain relief and well-being, whereas CTM being more effective in reducing neck pain and disability.
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Patient and healthcare professional engagement and time use within a randomised controlled trial: investigating intervention costs associated with remote person-centred care in Sweden
CONCLUSIONS: The intervention usage patterns of patients and HCPs differed. Despite HCPs being accessible when required, patients dedicated most of their time to self-care practices. Based on time distribution data, 15 full-time HCPs could potentially co-create, document and follow-up on health plans for 10 000 patients under study conditions.
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Economic evaluation of a person-centred care intervention with a digital platform and structured telephone support for people with chronic heart failure and/or chronic obstructive pulmonary disease: results from a randomised controlled trial in Sweden
CONCLUSIONS: The results of this CEA demonstrated that a remote PCC add-on intervention for people with COPD and/or CHF had lower healthcare costs and higher health-related quality of life compared with usual care.