-
Heat-sensitive moxibustion alleviates psychological craving in patients with methamphetamine addiction (withdrawal stage): a randomized controlled trial
CONCLUSION: Heat-sensitive moxibustion could alleviate psychological craving in patients with methamphetamine addiction (withdrawal stage), possibly through complex regulatory mechanisms involving multiple brain regions. →
-
Clinical dose-effect study of acupuncture at Lianquan (CV23) with different frequencies of twirling manipulation for post-ischemic stroke aphasia
CONCLUSION: Compared with the high-frequency twirling manipulation acupuncture at Lianquan (CV23), the low-frequency twirling manipulation acupuncture has a better effect in improving the language function, neurological function and quality of life in patients with post-ischemic stroke aphasia. →
-
Shake-Induced Temporary Ion-Pairing Between Lecithin and Glycolic Acid for Enhanced Exfoliation in a Novel Biphasic Serum: Comparative Ex Vivo and in Vivo Randomised Studies
CONCLUSION: The biphasic system successfully overcomes pH-dependent limitations of glycolic acid through temporary ion-pairing, providing enhanced exfoliation efficacy with a superior safety profile for consumer applications. →
-
Effect of intranasal breast milk administration on cerebral oxygenation, vital signs, and transition time to full oral feeding in preterm infants: a randomized controlled study
CONCLUSION: Intranasal breast milk administration has the potential to increase cerebral oxygenation in preterm infants. The maintenance of oxygen saturation and heart rate, along with good tolerance of the procedure, suggests that this intervention may be safe and feasible. →
-
Randomized Trial of Adjunctive Prednisolone for Kawasaki Disease
CONCLUSIONS: The addition of prednisolone to standard primary treatment for Kawasaki disease did not reduce the incidence of coronary-artery lesions at 1 month after illness onset. (Funded by the Chinese Academy of Medical Sciences Innovation Fund for Medical Sciences and the National Natural Science Foundation of China; ClinicalTrials.gov number, NCT04078568.). →
-
VC: Your First VC Meeting Will Be Agent-to-Agent | Auren Hoffman (Flex Capital)
The GTM Podcast is available on any major directory, including: Apple Podcasts Spotify YouTube Auren Hoffman (Flex Capital) joins the GTMnow podcast to share some of the most contrarian takes in tech today, from why AI moats are gone, to why your next VC meeting will be with a bot, to why AI is secretly… →
-
Computer-Assisted Colonoscopy in High-Adenoma Detection Rate Settings in a High-Risk Population: A Randomized Clinical Trial
CONCLUSIONS AND RELEVANCE: In this randomized clinical trial, CAD-assisted colonoscopy met noninferiority criteria for adenoma detection. Superiority was not statistically significant overall, with significant improvements limited to the exploratory FIT-positive subgroup, driven largely by diminutive adenomas. CAD also increased intensive surveillance assignments. The incremental benefit of CAD in reducing interval cancer risk requires further investigation. →
-
Pelvic Floor Workout for Preventing Stress Urinary Incontinence in Primiparous Women: A Randomized Clinical Trial
CONCLUSIONS AND RELEVANCE: In this multicenter randomized clinical trial, PEFLOW effectively reduced SUI incidence at 6 weeks post partum. This finding suggests that PEFLOW is effective in preventing SUI in pregnancy. →
-
Reducing light sensitivity during and between migraine attacks: A prospective study investigating spectral tuning of white light
BackgroundPhotophobia is experienced by most individuals with migraine, and it is frequently the most bothersome symptom other than headache. Light is not perceived uniformly; spectral composition and intensity influence discomfort and can exacerbate symptoms. While monochromatic green light shows therapeutic potential, it appears visually unnatural and is impractical for daily use. This study aimed to… →
-
A Phase 2b Multicenter Study to Evaluate Basmisanil as an Adjunctive Treatment in Patients With Cognitive Impairment Associated With Schizophrenia
Objective: Cognitive impairment associated with schizophrenia (CIAS) is a key driver of functional deficits in patients with this disorder. CIAS may involve deficient NMDA receptor-dependent neurotransmission. Negative allosteric modulators (NAMs) of γ-aminobutyric acid (GABA) type A (GABA(A)) α5 receptors enhance their activity and improve cognition in rodents and nonhuman primates. We tested whether prolonged treatment… →
