INTRODUCTION: In many countries, a high or increasing rate of sickness absence is challenging the sustainability of present sickness absence benefit schemes. Most sickness absence is certified on the grounds of common mental disorders or musculoskeletal disorders, and substantial effort has been invested in developing interventions promoting return to work for these patients. In Norway,… →

BACKGROUND: Prasinezumab has previously shown potential for reducing the progression of motor signs (Movement Disorder Society-sponsored Revision of the Unified Parkinson’s Disease Rating Scale [MDS-UPDRS] Part III) in patients with early-stage Parkinson’s disease who were treatment-naive or receiving monoamine oxidase type B (MAO-B) inhibitors. The aim of the PADOVA trial was to evaluate the efficacy… →

BACKGROUND: Tau PET imaging has emerged as a critical biomarker for Alzheimer’s disease, informing diagnosis, staging, and therapeutic selection. We investigated whether PET tracer selection alters tau detection. →

CONCLUSION: IORT to the resection cavity was associated with favorable local control and an acceptable safety profile. It may represent a feasible alternative to postoperative stereotactic radiosurgery in selected patients. →

CONCLUSION: A short-term dexamethasone sodium phosphate challenge is a safe, low-cost, and highly specific predictor of dexamethasone implant efficacy. This «test-and-treat» strategy may optimize resource allocation in resource-constrained settings by identifying responders before high-cost implantation. →

INTRODUCTION: Pemphigus vulgaris is a rare autoimmune blistering disease characterised by recurrent mucocutaneous erosions, high symptom burden and unpredictable relapse. Current management relies mainly on pharmacological therapy and hospital-based follow-up, with limited real-time monitoring and individualised support in home-based disease management. To address these challenges, this trial aims to evaluate the effectiveness of an Intelligent… →