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  • Empowering sexual self-care in HPV-positive women: A randomized trial of health belief model-Based education

    12 декабря, 2025

    CONCLUSION: Based on the results of the study, education based on the Health Belief Model has been effective in improving sexual self-care and enhancing the constructs of the model in women with human papillomavirus (HPV). Therefore, it is recommended that this theory be considered by healthcare providers and midwives when educating patients with human papillomavirus. →

    Clinical Trials
  • Can America Win the New Race for Scientific Leadership?

    12 декабря, 2025

    As geopolitical tensions rise, competition for the cutting-edge science and talent that underpins advanced technology has heated up. The United States, China, and other major powers now regard leadership in areas like AI, semiconductors, quantum technologies, and biotechnology as central to military capability, economic security, and ideological influence. Little wonder, then, that governments are pouring… →

    Management
  • Clinical outcomes of patients following apical surgery with retrograde root-end filling using two different materials

    11 декабря, 2025

    In certain clinical cases where orthograde treatment of chronic apical periodontitis is either impossible or ineffective, apical surgery with retrograde filling is considered the preferred method. When selecting a retrograde filling material, key factors such as biocompatibility, ability to provide a reliable seal, ease of use, and availability are taken into account. Despite numerous studies… →

    Clinical Trials
  • EFFICACY OF PROBIOTICS IN PREVENTING CHEMOTHERAPY-INDUCED DIARRHEA IN GASTROINTESTINAL CANCER PATIENTS

    11 декабря, 2025

    CONCLUSION: Probiotic in comparison to a placebo did not result in a statistically significant effect, suggesting a lack of benefit of administered probiotic for prevention of chemotherapy induced diarrhea among patients with gastrointestinal cancer. →

    Clinical Trials
  • Comparative Analysis of Postoperative Recovery and Analgesia in Gynecologic Laparoscopic Surgery with Total Intravenous Anesthesia Versus Combined Intravenous Inhalational Anesthesia Both with Ultrasound Guided Transversus Abdominis Plane Block: A Randomized Controlled Trial

    11 декабря, 2025

    CONCLUSION: TIVA combined with ropivacaine TAP block accelerates early recovery, improves analgesia, attenuates surgical stress, and reduces nausea/vomiting. →

    Clinical Trials
  • Effects of Esketamine-Dexmedetomidine Combination on Immediate Postprocedural Oxygenation Index in Severe Pneumonia Patients Undergoing Bedside Fiberoptic Bronchoscopic Sputum Aspiration: A Prospective Randomised Controlled Trial

    11 декабря, 2025

    CONCLUSION: Compared with conventional sedation protocols, the ESK-DEX combined regimen demonstrated superior OI preservation immediately after procedure, enhanced OI within 24 hours postoperatively, improved hemodynamic stability, and enhanced safety profile in severe pneumonia patients undergoing bedside FOB-guided suction therapy. This pharmacodynamic synergy addresses critical gaps in FOB sedation-simultaneously preventing hypoxemia, maintaining respiratory drive, and minimizing… →

    Clinical Trials
  • Traditional Chinese Medicine treatment with syndrome differentiation for patients with severe community-acquired pneumonia: a multicenter, randomized, placebo-controlled trial

    11 декабря, 2025

    CONCLUSION: Among patients with severe CAP, TCM treatment with syndrome differentiation reduced treatment failure, time to clinical stability, and the 28-d mortality and the 90-d mortality among patients admitted to the ward, without an increase in complications. →

    Clinical Trials
  • Network pharmacology-based analysis of the antithrombotic clinical efficacy and antithrombotic mechanism of Huoxue Jiedu prescription in the treatment of polycythemia vera with heat toxin and blood stasis syndrome

    11 декабря, 2025

    CONCLUSION: Network pharmacology predicted the corresponding targets of traditional Chinese medicine to a certain extent. Huoxue Jiedu prescription could enhance clinical efficacy, improve hematological indicators, and reduce coagulation indicators through antithrombotic effect by inhibiting the expression of PI3K and AKT1. →

    Clinical Trials
  • Real-World Effects of Home-Based Transcranial Direct Current Stimulation in Depression: A Randomized Controlled Trial of 3-Week Versus 6-Week Protocols

    11 декабря, 2025

    CONCLUSIONS: Both 3-week and 6-week active tDCS protocols were associated with improvements in depressive symptoms and cognitive function over time in this naturalistic clinical context; however, as the study did not include a sham control, these changes should be interpreted as comparative rather than causal effects. The 3- and 6-week protocols demonstrated similar therapeutic outcomes,… →

    Clinical Trials
  • Effects of Blueberry Supplementation on Depression and Anxiety Symptoms in a Rural Louisiana Population

    11 декабря, 2025

    Background/Objectives: Blueberries are an important nutraceutical due to their excellent nutritional profile, with particularly high levels of polyphenols and anthocyanins. These compounds can improve mood, cognition, and health. As such, blueberry consumption can potentially benefit those coping with depression and anxiety. In this regard, there is an unmet need for novel, effective, and accessible treatments… →

    Clinical Trials
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