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CONCLUSIONS: Probiotic supplementation may serve as an alternative supporting treatment, especially in the phenotype of women with a high FAI index. Probiotic therapy is also effective in reducing BMI in overweight women with PCOS.
Background/Objectives: Chronic low-grade inflammation is associated with insulin resistance and poor glycemic control, leading to the development of type 2 diabetes mellitus (T2DM). The present study investigated the effect of regular mango intake on inflammation and insulin sensitivity in participants with overweight or obesity and chronic low-grade inflammation. Methods: A human clinical study was performed…
There is limited understanding of how well patients adhere to postoperative instructions following ankle surgery, particularly in outpatient settings regarding partial weight bearing (15-30 kg) and orthosis use. This study aims to assess orthosis compliance and load frequency over six weeks post-surgery using pressure-sensitive insoles, while also evaluating the effectiveness of continuous biofeedback. A total…
CONCLUSIONS: A novel educational intervention about ICI risks and benefits was feasible to deliver, deemed acceptable, and shows promise in improving knowledge and activation to ask questions without increasing anxiety. A future study evaluating UPLIFT’s efficacy in these and other outcomes, including severe ICI toxicity, is warranted.
CONCLUSIONS: Both the CSCLR and TFM methods can yield accurate treatment centration and satisfactory visual quality. However, the CSCLR method may contribute to less horizontal decentration in patients with a large preoperative pupil offset. [J Refract Surg. 2025;41(2):e144-e154.].
CONCLUSIONS: Both IOLs showed good and comparable distance and intermediate visual acuities but near vision was better for the HP IOL. This model provided higher spectacle independence for near vision. [J Refract Surg. 2025;41(3):e102-e113.].
Children with Juvenile Idiopathic Arthritis (JIA) are at a currently unpredictable risk of a blinding, often asymptomatic, co-existent eye disorder, anterior uveitis which requires prompt treatment. The unpredictability of this insidious disorder commits children with JIA to three-monthly expert clinical examinations in specialist eye centres often located far from their homes. Optical coherence tomography of…
The aim of this study was to assess the impact of orthodontic treatment with orthodontic aligners (OAs) and fixed appliances (FAs) on oral health-related quality of life (OHRQoL). This parallel randomized clinical trial included 40 male and female patients aged 13 to 35 years diagnosed with Angle’s Class I malocclusion. Participants were assigned to two…
CONCLUSIONS AND RELEVANCE: In this randomized clinical trial, results of the primary, intention-to-treat analysis showed that interpreters’ overall interpreting communication quality did not improve in the intervention group compared with controls, but in the secondary, per-protocol analysis, it was improved when at least 70% of the training was completed. These findings suggest that an online…
CONCLUSIONS: Using data collected with CAT surveys, we calculated an MIC of 3 points for the NIH RTF impact score, and estimates ranged from 1.3 to 7.2 depending on the baseline impact score and statistical approach used. These findings are consistent with previous MIC estimates that were based on non-adaptive short form surveys and have…