Clinical Trials
Category Added in a WPeMatico Campaign
-
Efficacy and safety of combined loratadine and mometasone furoate therapy in allergic rhinitis patients
CONCLUSION: The combination of loratadine and mometasone furoate effectively alleviates clinical symptoms in patients with allergic rhinitis while demonstrating a favorable safety profile, making it a promising option for clinical use.
-
Long-term Progressive Improvement of Atopic Dermatitis by an Herbal Emollient Plus Combination in a 12-week Clinical Trial
Atopic dermatitis is a chronic inflammatory skin disease characterized by flare-ups of inflamed, dry, and itchy skin affecting over 200 million people worldwide. «Emollients plus» containing active cosmetic ingredients such as herbal extracts and phytochemicals have the potential to surpass the efficacy of conventional emollients, while avoiding side effects associated with pharmacological interventions. The reported…
-
Impact of AI-Assisted Diagnosis on American Patients’ Trust in and Intention to Seek Help From Health Care Professionals: Randomized, Web-Based Survey Experiment
CONCLUSIONS: Despite AI’s growing role in medicine, patients still prefer human-only expertise, regardless of partisanship and demographics, underscoring the need for strategies to build trust in AI technologies in health care.
-
Serious Illness Conversations in the Emergency Department for Older Adults With Advanced Illnesses: A Randomized Clinical Trial
CONCLUSIONS AND RELEVANCE: In this randomized clinical trial of seriously ill older adults in the ED, while a nurse-led SIC intervention did not significantly improve patient-reported engagement in ACP, it did increase clinician-documented SICs in the medical records. ED visits may serve as a critical access point to enhance SICs for seriously ill yet clinically…
-
What is the impact on recruitment of a shortened compared with a standard-length participant information leaflet? PROMETHEUS in IBD-BOOST: study within a trial, a decentralised UK randomised controlled trial
CONCLUSION: We did not find evidence of a significant difference between RCT recruitment and retention rates in participants randomised to the standard-length PIL compared with the shortened. It may be that a shortened PIL has the same effect on recruitment and retention outcomes, providing that the trial does not require extensive information for other reasons…
-
The effect of virtual reality on skin prick test-related pain and fear in children: a randomized controlled trial
CONCLUSION: Virtual reality can be an effective tool in pediatric allergy clinics to reduce pain and fear during skin prick testing. By enhancing the child’s comfort, VR may also improve adherence to allergy follow-up and treatment, ultimately contributing to better clinical outcomes.
-
EEG-Guided Adaptive Learning: A New Neuroeducational Approach to the Facilitation of Cognitive Control in ADHD Children
CONCLUSION: EEG-guided adaptive learning is an effective and engaging intervention that improves cognitive functioning and academic performance in children with ADHD. It is important to note that although increases in frontal alpha power were observed, which are typically associated with improved executive functioning, such increases can also be linked to anxiety and depression. This potential…
-
Effect of tuina at different muscle positions on surface electromyography in chronic nonspecific neck pain: A randomized clinical study
CONCLUSIONS: Both the muscle-start-end tuina and muscle belly tuina techniques demonstrate efficacy in treating chronic nonspecific neck pain. However, the muscle-start-end tuina method exhibits superior outcomes in symptom alleviation, muscle tension reduction, and enhancement of muscle endurance compared to muscle belly tuina.
-
In-home Tele-assessment for Autism in Toddlers: Validity, Reliability, and Caregiver Satisfaction with the TELE-ASD-PEDS
CONCLUSION: In-home use of the TAP is valid, reliable, feasible, and acceptable to caregivers. Findings support the continued use of telehealth assessment for autism in toddlers, which can reduce disparities in access to timely diagnostic services.
-
Erenumab for Chronic Cluster Headache: A Randomized Clinical Trial
CONCLUSIONS AND RELEVANCE: In this clinical trial of patients with CCH, blockade of the CGRP receptor with erenumab was not successful in the prophylaxis of attacks. Future studies should revisit the role of CGRP in CCH.