Clinical Trials
Category Added in a WPeMatico Campaign
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Cost-Effectiveness of the START Hospital Addiction Consultation Service for Opioid Use Disorder Treatment
CONCLUSIONS AND RELEVANCE: In this trial-based economic evaluation, START was a cost-effective approach for addressing opioid use disorder in the inpatient setting by increasing the initiation of medication for OUD and linkage to OUD-focused care after discharge.
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Effect of diode laser pretreatment on dentin thickness and discoloration in deep caries treated with biodentine: a randomized clinical trial
Preserving pulp vitality in deep carious lesions remains a clinical challenge. Indirect pulp capping with bioactive calcium silicate materials such as Biodentine has shown favorable biological outcomes, while diode laser irradiation has been proposed as an adjunct to enhance hemostasis, disinfection, and pulpal healing. However, evidence regarding their combined use is limited. This randomized controlled…
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The Effects of Pilates-Based Tele-Exercise on Physical and Mental Health in Primary Dysmenorrhea
CONCLUSION: The findings demonstrate that Pilates-based tele-exercises significantly enhance the overall health and well-being of women with primary dysmenorrhea. This is achieved through improved menstrual symptoms and positive changes in attitudes toward menstruation. These results suggest that PBTE could be an effective non-pharmacological approach to managing primary dysmenorrhea.
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Examination of the Effect of Emotional Freedom Technique on Quality of Life and Symptoms in Dysmenorrhea
CONCLUSION: It was determined that EFT reduces pain, alleviates symptoms, and enhances quality of life in women with dysmenorrhea symptoms.
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Effect of Vimala infant massage on mothers with postpartum depression
CONCLUSIONS: Vimala IM is an effective intervention in reducing PPD symptoms, particularly self-blame. The absence of a partner increased the risk of developing PPD by up to 4 times.
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Psychoeducation among women with breast cancer and emotional symptoms
CONCLUSION: The psychoeducational workshops demonstrated effectiveness to decrease the symptom burden for anxiety and depression. Early education and counselling for recently diagnosed BC patients should be considered part of the treatment to prevent and decrease these symptoms.
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Persistent Vomiting Among Children With Acute Gastroenteritis: A Secondary Analysis of a Randomized Clinical Trial
CONCLUSIONS AND RELEVANCE: In this analysis of children presenting for ED care with vomiting, younger children and those unwell for 24 to 48 hours with 10 or more episodes of vomiting at presentation were more likely to have persistent vomiting after discharge. Based on these findings, these children are most likely to benefit from being…
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Efficacy of a Modular Lifestyle Intervention Through Occupation for Individuals With Rheumatoid Arthritis: A Randomized Controlled Trial With 6-Month Follow-Up
CONCLUSIONS AND RELEVANCE: The LI produced durable improvements in occupational performance and patient-reported outcomes, supporting its integration as a sustainable adjunct to pharmacological care for individuals with RA. Plain-Language Summary: People with rheumatoid arthritis often have difficulty completing daily activities because of pain, fatigue, and limitations in movement. This study explored whether a structured lifestyle…
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Efficacy and Safety of Non-Cross-Linked Hyaluronic Acid Mesotherapy for Post-Acne Erythema: A Split-Face, Prospective, Randomized, Single-Center Trial
CONCLUSION: According to the results of this study, non-cross-linked HA mesotherapy is a promising and useful therapeutic option for PAE.
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Clinical controlled study of Zhongyi Ointment() in the treatment of Kellgren-Lawrence grade knee osteoarthritis with moderate-to-severe pain
CONCLUSION: Zhongyi Ointment() can rapidly and significantly improve symptoms in patients with K-L gradeⅡknee osteoarthritis with moderate-to-severe pain during the acute exacerbation stage, with definite short-term efficacy and favorable safety. Continuous treatment helps to consolidate the therapeutic effect and warrants further validation through multicenter studies with large sample sizes, as well as investigations into the…