Clinical Trials
Category Added in a WPeMatico Campaign
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Efficacy of Botulinum Toxin A for the Management of Melasma: A Split-Face, Randomized Control Study
CONCLUSION: Intradermal incoBoNT-A injection combined with TCC demonstrated superior efficacy in melasma treatment and recurrence prevention compared to TCC monotherapy.
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Long-term effect of CoDuSe program on balance, fall risk, and gait in patients with multiple sclerosis
CONCLUSION: The CODuSe program, when combined with a standard exercise routine, has a long-lasting effect on balance, fall risk (up to 24 weeks), and gait ability (up to 16 weeks) in patients with MS.
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Effects of integrating Feldenkrais method with dynamic neuromuscular stabilization exercises on clinical outcomes in older women with nonspecific chronic low back pain: A randomized controlled trial
CONCLUSION: Both interventions effectively alleviated pain and fear of movement while enhancing lumbar range of motion in older women with chronic low back pain. The combined intervention, integrating the Feldenkrais Method with Dynamic Neuromuscular Stabilization exercises, yielded superior clinical outcomes, supporting its incorporation into rehabilitation programs to improve functional independence and quality of life.
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The role of probiotics and dietary interventions in the treatment of periodontitis: a pilot randomized controlled clinical trial
CONCLUSION: Probiotics were found to support periodontal healing, and this effect was significantly enhanced by a personalized anti-inflammatory diet. It is recommended that probiotics and balanced nutrition be integrated into a holistic approach in the treatment of periodontitis.
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Immediate efficacy of low-intensity focused ultrasound versus planar ultrasound in patients with myofascial pain syndrome of upper trapezius: a randomized controlled clinical trial
CONCLUSION: Both LIFU and LIPU can be considered effective therapeutic options, offering immediate symptom relief in patients with upper trapezius MPS.
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Distress screening in patients with high-grade glioma: diagnostic accuracy in relation to a structured clinical interview in a multicenter cluster-randomized controlled trial
CONCLUSION: While all three tools performed better than random chance, none demonstrated convincing discriminative ability in identifying psychiatric comorbidities. In practice, screening tools can identify a substantial proportion of patients with mental disorders, however at the cost of a considerable number of false negatives.
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Impacts of acupuncture and moxibustion combined with ABCLOVE voice training on voice function and inflammatory factor levels in patients with vocal cord polyp operation
Objective:To explore the impacts of acupuncture and moxibustion combined with ABCLOVE voice training on voice function and the levels of inflammatory factors in patients who were diagnosed with vocal cord polyp and received operation. Methods:A total of 96 cases who received operation on vocal cord polyp were randomly assigned into two groups. The control group…
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Spinal needles versus conventional needles for fine-needle aspiration biopsy of thyroid nodules-A multicenter randomized controlled trial
CONCLUSIONS: No significant improvement was found using spinal needles with a stylet compared to conventional needles. Given the significantly higher cost of spinal needles and comparable diagnostic outcomes, their routine use for thyroid FNAB is not recommended.
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Cost Analysis of the PARENT Trial of Community Health Workers in Early Childhood Preventive Care: A Secondary Analysis of a Cluster-Randomized Clinical Trial
CONCLUSIONS AND RELEVANCE: This secondary analysis of a cluster-randomized clinical trial suggests that the cost of the PARENT intervention was offset by savings in non-WCV health care utilization, and revenue for federally qualified health centers from increased WCV attendance could fund ongoing intervention costs.
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Efficacy and safety of commercially available cosmetic perioperative skincare products for non-invasive energy-based device treatment: a single-centre, randomized, placebo-controlled trial
Photoelectric therapies (or non-invasive energy-based device treatment), especially picosecond lasers and intense pulsed light (IPL) treatments, are widely used to manage various cutaneous conditions, including pigmentation, inflammation, and signs of aging. However, these treatments can also impair the integrity of the skin barrier, making post-treatment repair of skin barrier function essential to maintain perioperative curative…