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  • Long-pulsed nd: YAG laser treatment of nail psoriasis: clinical and ultrasonographic assessment

    9 июня, 2024

    Nail psoriasis is a chronic, inflammatory condition which is difficult to treat, linked with greater psoriasis severity, and may be associated with anxiety and significant functional impairment of the quality of life. The 1064 nm Nd: YAG laser was reported to yield satisfactory results in the treatment of nail psoriasis.The aim of the study was… →

    Clinical Trials
  • DiffUCO: A Diffusion Model Framework for Unsupervised Neural Combinatorial Optimization

    8 июня, 2024

    Sampling from complex, high-dimensional target distributions, such as the Boltzmann distribution, is crucial in many scientific fields. For instance, predicting molecular configurations depends on this type of sampling. Combinatorial Optimization (CO) can be seen as a distribution learning problem where the samples correspond to solutions of CO problems, but it is challenging to achieve unbiased… →

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  • Effects of intensive lifestyle changes on the progression of mild cognitive impairment or early dementia due to Alzheimer’s disease: a randomized, controlled clinical trial

    8 июня, 2024

    CONCLUSIONS: Comprehensive lifestyle changes may significantly improve cognition and function after 20 weeks in many patients with MCI or early dementia due to AD. →

    Clinical Trials
  • Dapagliflozin reduces systemic inflammation in patients with type 2 diabetes without known heart failure

    8 июня, 2024

    OBJECTIVE: Sodium glucose cotransporter 2 (SGLT2) inhibitors significantly improve cardiovascular outcomes in diabetic patients; however, the mechanism is unclear. We hypothesized that dapagliflozin improves cardiac outcomes via beneficial effects on systemic and cardiac inflammation and cardiac fibrosis. →

    Clinical Trials
  • Dose escalation of tolinapant (ASTX660) in combination with standard radical chemoradiotherapy in cervical cancer : a study protocol for a phase 1b TiTE-CRM clinical trial (CRAIN) in UK secondary care centres

    8 июня, 2024

    BACKGROUND: Cervical cancer is the fourth most common cancer in women, with an estimated 342,000 deaths worldwide in 2020. Current standard of care in the UK for locally advanced cervical cancer is concurrent chemoradiotherapy with weekly cisplatin, yet 5-year overall survival rates are only 65% with a distant relapse rate of 50%. Inhibitors of Apoptosis… →

    Clinical Trials
  • The incidence and intensity of postoperative pain and Flare-up following the use of three different intracanal medicaments in teeth with posttreatment apical periodontitis: a randomized clinical trial

    8 июня, 2024

    CONCLUSIONS: Similar postoperative pain incidence in all experimental groups indicates that all three medicaments are clinically acceptable in inter-appointment management of retreatment cases in terms of post-endodontic pain and flare-up. →

    Clinical Trials
  • Exploring relationships with food after dietary intervention in patients with colorectal cancer: a qualitative analysis from the Protein Recommendations to Increase Muscle (PRIMe) trial

    8 июня, 2024

    CONCLUSION: This qualitative study explored the emotional and psychological effects of a clinical nutrition trial on patients, focusing on their relationship with food. It underscored the trial’s comprehensive intervention and its enduring influence on patients, extending beyond the immediate intervention phase. The role of current perspectives, motivation, and knowledge acquisition on ability to adhere to… →

    Clinical Trials
  • Saccharomyces boulardii combined with triple therapy alter the microbiota in the eradication of Helicobacter pylori infection

    8 июня, 2024

    To assess the effectiveness and safety of combining Saccharomyces boulardii powder with triple therapy as a primary approach for eradicating H. pylori infection, a total of 144 patients who tested positive for H. pylori and diagnosed with non-ulcer dyspepsia underwent endoscopy at two national centers between June 2017 and March 2019 were included. The patients… →

    Clinical Trials
  • Additional copies of 1q negatively impact the outcome of multiple myeloma patients and induce transcriptomic deregulation in malignant plasma cells

    8 июня, 2024

    Additional copies of chromosome 1 long arm (1q) are frequently found in multiple myeloma (MM) and predict high-risk disease. Available data suggest a different outcome and biology of patients with amplification (Amp1q, ≥4 copies of 1q) vs. gain (Gain1q, 3 copies of 1q) of 1q. We evaluated the impact of Amp1q/Gain1q on the outcome of… →

    Clinical Trials
  • Whisper WebGPU: Real-Time in-Browser Speech Recognition with OpenAI Whisper

    8 июня, 2024

    Achieving real-time speech recognition directly within a web browser has long been a sought-after milestone. Whisper WebGPU by a Hugging Face Engineer (nickname ‘Xenova’) is a groundbreaking technology that leverages OpenAI’s Whisper model to bring real-time, in-browser speech recognition to fruition. This remarkable development is a monumental shift in interaction with AI-driven web applications. The… →

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    AI, AI Business, AI Education, AI Healthcare, AI Help, AI in Finance, AI Libs, AI Marketing, AI Product, AI Research, AI Sales, AI Staff, AI Startup, AI Tech, AI UX, Automation, Edge AI, Explainable AI, Natural Language Processing, NLP, No-code AI, Open Source AI, Quantization, Transform AI, XAI
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