CONCLUSIONS: Ada demonstrated a higher diagnostic accuracy than Symptoma, and substantially more patients would recommend Ada and assessed Ada as easy to use. The high number of unrecognized potentially life-threatening diagnoses by both SCs and inappropriate triage advice by Ada was alarming. Overall, the trustworthiness of SC recommendations appears questionable. SC authorization should necessitate rigorous… →
CONCLUSIONS: This represents the methodological design for the first evaluation of CT-152 as an adjunct to ADT. This study protocol is methodologically robust and incorporates many aspects of conventional pivotal pharmaceutical phase 3 trial design, such as randomization and safety end points. Novel considerations included the use of a sham comparator, masking considerations for visible… →
Our aim was to find out whether speech-related temporal parameters (SRTPs) are sensitive indicators of the clinical outcome in acetylcholinesterase (AChE) inhibitor therapy with donepezil, compared to the standard cognitive Alzheimer’s Disease Assessment Scale-Cognitive Subscale (ADAS-Cog) used in clinical trials. In this 24-week-long, naturalistic, self-control, open-labeled, prospective pilot study with 10 mg donepezil on 20… →
Data visualizations (DVs) have become a common practice in the big data era, utilized by various applications and institutions to convey insights from massive raw data. However, creating suitable DVs remains a challenging task, even for experts, as it requires visual analysis expertise and familiarity with the domain data. Also, users must master complex declarative… →
Automated design in artificial intelligence (AI) is an emerging field focusing on developing systems capable of independently generating and optimizing their components. This approach is built on the premise that machine learning can surpass the limitations of manual design, enabling the creation of more efficient, adaptable, and powerful AI systems. The aim is to allow… →
Data centers are poised to be among the world’s largest electricity consumers. If there is no meaningful change, they will consume between 10% and 20% of the electricity used in the U.S. by 2030. This explosive energy demand is influenced by the increasing computational demand, especially for new generative AI applications. Growth at this rate… →
CONCLUSIONS AND RELEVANCE: In this randomized clinical trial of an app-based intervention for anxiety, the primary hypothesis that improvement in anxiety would be greatest in the condition using gain of points plus social incentives was not supported; however, the results suggest that a CBT application incorporating a full suite of CBT skills and embedded user… →
CONCLUSION: Combined treatment with compound fluocinolone acetonide cream and guaiazulene demonstrates excellent efficacy and feasibility in the management of neurodermatitis. Compared to standard treatment alone, it yields superior clinical outcomes. →
Language models (LMs), while powerful in generating human-like text, often produce unstructured and inconsistent outputs. The lack of structure in responses poses challenges in real-world applications, especially in long and extensive responses. It becomes difficult to extract specific information, integrate with systems expecting structured data, and present information in formats like tables or lists that… →
Quantum computing has shown great potential to transform specific algorithms and applications and is expected to work alongside traditional High-Performance Computing (HPC) environments. Moreover, Noisy Intermediate-Scale Quantum (NISQ) devices have emerged as powerful computational platforms, but they face challenges such as limited qubit coherence times and a high chance of errors. Due to the complexity… →