Generating all-atom protein structures is a significant challenge in de novo protein design. Current generative models have improved significantly for backbone generation but remain difficult to solve for atomic precision because discrete amino acid identities are embedded within continuous placements of the atoms in 3D space. This issue is especially significant in designing functional proteins,… →

Enzymes are indispensable molecular catalysts that facilitate the biochemical processes vital to life. They play crucial roles across metabolism, industry, and biotechnology. Despite their importance, there are significant gaps in our knowledge of these catalysts. Out of the approximately 190 million protein sequences cataloged in databases like UniProt, fewer than 0.3% are curated by experts,… →

Customer service teams face significant challenges in today’s fast-paced business environment. They must handle a growing number of customer inquiries while maintaining a high standard of service. Balancing these demands is difficult, especially with tools that lack integration and real-time support. The result is often delays, inefficiencies, and unmet customer expectations. As businesses scale, equipping… →

Artificial Intelligence (AI) is transforming how businesses operate, offering unprecedented efficiency, innovation, and customer satisfaction. By automating repetitive tasks, providing insights from vast datasets, and enhancing decision-making, AI has become an indispensable tool for modern businesses. From streamlining customer support to optimizing supply chains and driving personalized marketing campaigns, the adoption of AI tools is… →

The integration of artificial intelligence into everyday life faces notable hurdles, particularly in multimodal understanding—the ability to process and analyze inputs across text, audio, and visual modalities. Many models require significant computational resources, often relying on cloud-based infrastructures. This reliance creates challenges in terms of latency, energy efficiency, and data privacy, which can limit their… →

Software has been a critical catalyst for economic growth over the past several decades, a phenomenon prominently articulated by Andreessen in his influential blog post, “Why software is eating the world.” The technological landscape is now witnessing another transformative wave with Artificial Intelligence, particularly Large Language Models (LLMs), poised to revolutionize the existing software ecosystem.… →

Video and Image generation innovations are improving the quality of visuals and focusing on making AI models more responsive to detailed prompts. AI tools have opened new possibilities for artists, filmmakers, businesses, and creative professionals by achieving more accurate representations of real-world physics and human movement. AI-generated visuals are no longer limited to generic images… →

In machine learning, reliable predictions and uncertainty quantification are critical for decision-making, particularly in safety-sensitive domains like healthcare. Model calibration ensures predictions accurately reflect true outcomes, making them robust against extreme over- or underestimation and facilitating trustworthy decision-making. Predictive inference methods, such as Conformal Prediction (CP), offer a model-agnostic and distribution-free approach to uncertainty quantification… →

A notable aspect of peripheral responses in the animal nervous system is localization, where the linear receptive fields of simple-cell neurons respond to specific, contiguous regions much smaller than their total input domain. However, localization poses a critical challenge in understanding neural information processing across sensory systems. Traditional machine learning approaches generate weight distributions, that… →