To explore the effects of mindfulness training on emotion and sleep quality in patients with colorectal cancer. A total of 44 patients diagnosed with colorectal cancer from a hospital in Chongqing were recruited between August 2021 and April 2023. These participants were randomly assigned to either a training group or a waiting group using a… →

BACKGROUND: Patients with relapsed or refractory T-cell acute lymphoblastic leukaemia have limited responses to conventional chemotherapy and poor prognoses. T-cell precursors exhibit high expression of BCL-2 and are sensitive to BCL-2 inhibitors. Retrospective case series have reported the successful use of venetoclax combined with chemotherapy or hypomethylating agents when treating relapsed or refractory T-cell acute… →

CONCLUSIONS: The nsPFA exhibited noninferior efficacy and comparable safety to AI-guided RFA while obviating the need for general anesthesia. Furthermore, the study revealed that this ablation technique significantly reduced both total procedure time and left atrial dwelling time. (InsightPFA Trial of the LotosPFA Catheter [InsightPFA]; NCT06014996). →

CONCLUSION: The PAAP was considered cost-effective, but significant uncertainty remained. Future trials with adequate power and longer follow-up are needed to determine the most cost-effective models for penicillin allergy testing. →

CONCLUSIONS: Women notified of their dense breasts felt anxious and confused, did not feel more informed to make decisions about their breast health, and wanted to be guided by their general practitioners. Notification of breast density as part of population based breast screening may have adverse outcomes including additional consultation burden on general practitioners to… →

CONCLUSIONS: A 5-day regimen of ketamine infusion was associated with the best outcome for pain control and minimal side effects. Meanwhile, the 7-day regimen of ketamine infusion had the greatest number of side effects. The 3-day period of infusion had the lowest number of side effects and offered the least pain control. →

CONCLUSION: Our findings suggest that a main study with a proper sample size based on this study investigating TENS1 may reveal if this set of frequencies reduces pain in laboring women.Clinical Relevance — This study suggests relevance of considering non-pharmacologic and neuromodulating approach in labor pain management. →

CONCLUSION: CO(2) cystoscopy is a safe, efficient, and diagnostically effective alternative to conventional saline cystoscopy following gynecologic laparoscopy. Its use significantly reduces procedural time without compromising the detection of urinary tract injuries and avoids the need for additional agents such as dyes or diuretics. These findings support the integration of CO(2) cystoscopy into routine intraoperative… →