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O04 Mission EB -mesenchymal intravenous stromal cell infusions in children with recessive dystrophic epidermolysis bullosa: a randomised, double-blinded, placebo controlled, crossover trial
Recessive Dystrophic Epidermolysis Bullosa (RDEB) is a severe type of epidermolysis bullosa resulting from mutations in COL7A1 gene. Patients experience various degrees of blistering following minor trauma which can over time lead to fibrosis, limb contractures and an increased risk of developing squamous cell carcinoma. The aim was to assess if repeated infusions of allogeneic… →
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Comparison between two bone anchored force systems for correction of skeletal Class II malocclusion in growing patients: a randomized controlled clinical trial, part 2: short-term dentoalveolar changes
CONCLUSIONS: The use of either pushing or pulling force mechanics using bimaxillary skeletal anchorage was effective in improving Class II dental relationships without dentoalveolar side effects. Pretreatment transverse discrepancy should be assessed to incorporate maxillary expansion into the treatment protocol for patients diagnosed with maxillary arch constriction. →
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AI Coding Tools: The Productivity Trap Most Companies Miss
Have your engineering teams embraced generative AI for coding projects? If not, they likely will soon. But there’s a paradox: While these tools can deliver real productivity gains, they can also create hidden risks that could cripple your systems months or even years later. In this video, MIT Sloan Management Review features editor Kaushik Viswanath… →
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Effect of Ephedrine versus Phenylephrine on Postoperative Delirium in Elderly Patients Undergoing Total Hip or Knee Arthroplasty: A Randomized Controlled Trial
CONCLUSION: In conclusion, among elderly patients undergoing hip or knee arthroplasty, the use of ephedrine to correct intraoperative hypotension was associated with a reduced incidence of POD within three days compared to phenylephrine. However, the absence of cerebral oxygen saturation monitoring and the limited follow-up period of only three days for POD assessment represent significant… →
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Exploring the predictors and barriers to accepting smoking cessation support within a targeted lung health check setting
BACKGROUND: The Quit Smoking Lung Health Intervention Trials (QuLIT-1 and -2), and other studies, show that providing immediate smoking cessation support within lung cancer screening services substantially improves quit rates. However, in the QuLIT2 trial, only around half of those offered smoking cessation support actually accepted it. Understanding what underpins this and how to facilitate… →
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How Procter & Gamble Uses AI to Unlock New Insights From Data
Carolyn Geason-Beissel/MIT SMR | Getty Images Few organizations can legitimately claim to have been doing analytical research for over a century. But in 1924, Procter & Gamble CEO William Cooper Procter asked Paul “Doc” Smelser, an economist at P&G for 34 years, to find out how many customers used Ivory soap to clean their bodies… →
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Functional Outcomes Across High-Risk OCT-Based Phenotypes in Intermediate Age-Related Macular Degeneration-PINNACLE Study Report 11
CONCLUSIONS: Integrating comprehensive analyses of structural OCT biomarkers with functional assessments revealed distinct phenotypic subtypes of iAMD that are associated with significant functional deficits. Particularly, early atrophy markers should be considered for patient selection and risk assessment in clinical trials and routine practice. →
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Guide to Underwater Image Enhancement Using OpenCV
Have you ever captured amazing underwater footage, only to discover that your photos were plagued by poor visibility, muted colours, and a bluish-green haze? You’re not by yourself. As depth increases, warmer colours such as red, orange, and yellow are absorbed first, leaving images looking dull and low in contrast. In this post, we are… →