CONCLUSIONS: RIC intervention with 5-min ischemia-reperfusion cycles is safe. RIC is also safe when extended to extremely preterm neonates with confirmed medical or surgical NEC. →

The proper assessment of cognitive functioning is the subject of numerous scientific studies. Current behavioral methods essentially preclude this assessment in patients with disorders of consciousness (DOC). However, the development of eye-tracking technology (ETT) and the establishment of contact via this channel have created an opportunity to diagnose the cognitive function (CF) of DOC patients.… →

CONCLUSION: This prospective individual participant data pooled analysis provides further evidence that the quadpill strategy is superior to initial monotherapy by virtue of improved BP-lowering, less need for uptitration and being associated with less treatment inertia. →

The aim of this study was to provide health interventions by integrating the Diabetes Self-Management Education and Support recommended by the American Diabetes Association with Orem’s self-care model to address the challenges in diabetes self-management. This research is a randomized controlled experimental research. Sixty-five diabetic patients (30 controls, 35 experimental) were included in the study.… →

CONCLUSIONS: The study demonstrated that listening to music had no significant effect on pain and anxiety in patients undergoing TRUS-PBx. Conversely, the findings showed that engaging patients in conversation significantly reduced pain and anxiety during the procedure. →

CONCLUSIONS: PR margins at or 1 mm apical to the CEJ provided similar clinical and esthetic outcomes when combined with CAF + CTG. The CEJ-1 approach improved early patient comfort without compromising root coverage. →

CONCLUSION: There was improvement in the parameters analyzed regarding the vaginal microbiota in the intervention with FRAXX with a higher proportion of Lactobacillus and a decrease in pH. And there was no superiority of FRAXX in relation to the use of topical estriol. →

CONCLUSION: At the sample level, DBT-ST yielded larger and more durable gains than SSGT-primarily among adults-whereas adolescent effects were smaller, heterogeneous and not consistently significant. Long-term endpoints addressed symptoms and diagnostic status; NSSI episode frequency was not quantified longitudinally. Anxiety diagnoses increased in both arms, underscoring the need for routine anxiety screening and targeted management… →

CONCLUSIONS: Exercise intervention during paclitaxel therapy significantly reduced PIPN severity and improved quality of life. Findings are preliminary and warrant further confirmation. →

Vonoprazan, a novel and potent acid suppressant, has recently been incorporated into Helicobacter pylori eradication regimens. However, the data on combination of vonoprazan with levofloxacin remains scarce. This study represents one of the first evaluations comparing 7-day and 14-day once-daily regimens containing vonoprazan, levofloxacin, clarithromycin-MR, and bismuth for H. pylori eradication in regions characterized by… →