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A Phase Ib Case Series Using Bortezomib With Chemotherapy in Atypical Teratoid/Rhabdoid Tumors
CONCLUSIONS: The toxicities were no more than expected with chemotherapy alone. Adding bortezomib to treatment of ATRT is feasible. →
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Colchicine to prevent cardiovascular events in thoracic surgery patients with or without coronary artery disease: a secondary analysis
CONCLUSIONS: Patients with CAD undergoing thoracic surgery had a higher risk of MINS and other ischaemic outcomes than non-CAD patients. There was no evidence that the effect of colchicine differed between patients with and without CAD; however, these analyses were limited by sample size and do not exclude modest differences between subgroups. →
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How B2B Marketers Misunderstand Their Customers
Nick Lowndes/Ikon Images Businesses are striving to adapt ever faster to keep pace with rapid change, and yet B2B marketing practices have remained surprisingly static. Sure, the tactics have shifted to digital executions, and the use of data has made targeting B2B buyers more precise, but marketers remain rooted in fundamentally flawed assumptions about the… →
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Teaching Acute Coronary Syndrome High-Risk ECG Interpretation and Clinical Decision-Making Through FOAMed Videos and Podcast Versus Print-Based Materials Among Emergency Care Providers: Randomized Controlled Mixed Methods Trial
CONCLUSIONS: This study is innovative in directly comparing a curated FOAMed multimedia module with selected print-based materials in an interprofessional emergency care population. It differs from existing research by focusing on subtle, emerging ischemic patterns and evaluating realistic, time-limited self-learning formats. The findings provide evidence that curated FOAMed resources can produce greater short-term improvements in… →
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Assessing the accuracy and efficiency of an electronic platform for managing childhood illnesses in rural China: A cluster randomized controlled trial
CONCLUSIONS: The eIMCI platform shows potential in enhancing IMCI implementation and significantly reducing the training burden in resource-limited settings. Trial registration: Chinese Clinical Trial Registry: ChiCTR2100042533, https://www.chictr.org.cn/showproj.html?proj=119995. →
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Effectiveness of symptom map-based education in the management of premenstrual syndrome: a randomized controlled trial
CONCLUSION: A symptom map-based educational intervention is a clinically applicable, non-pharmacological approach for PMS management. This structured education appears especially beneficial for women with more severe baseline symptoms and may be integrated into routine gynecological care to support individualized symptom management. →
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Longitudinal Prediction of Retinal Sensitivity Based on Disease Progression Quantified From Optical Coherence Tomography in Geographic Atrophy
CONCLUSIONS: Two exploratory endpoints were developed, namely quantification of EZ thickness and loss, and localized RS within high-risk OCT areas. RS decline during follow-up is associated with automatically quantified disease progression in OCT. →
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Influence of dance therapy mode of intangible cultural heritage on children’s emotional regulation and psychological wellbeing: a randomized controlled intervention study
CONCLUSION: The dance therapy mode of intangible cultural heritage has a significant positive impact on children’s emotional adjustment ability and psychological and social development. This intervention will integrate physical activities, emotional release, group participation and cultural identity to enhance children’s mental health, and open up a non-medical intervention path with structure, safety and cultural connotation.… →
