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Google Introduces Open-Source Full-Stack AI Agent Stack Using Gemini 2.5 and LangGraph for Multi-Step Web Search, Reflection, and Synthesis
«`html Google Introduces Open-Source Full-Stack AI Agent Stack Using Gemini 2.5 and LangGraph for Multi-Step Web Search, Reflection, and Synthesis The Need for Dynamic AI Research Assistants Conversational AI has evolved significantly, yet many large language models (LLMs) still face limitations. They generate responses based solely on static training data and lack the capability to… →
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Four months of treatment with anakinra combined with glucocorticoids for giant cell arteritis: a multicenter, randomized, double-blind, placebo-controlled trial
CONCLUSIONS: Although prematurely discontinued, this study does not support the use of 4 months of treatment with anakinra combined with GCs to reduce the risk of relapse or GC exposure. →
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Effects of a single session of in-person and remote strength training on low back pain and disability outcomes in pregnant women: a randomized and controlled crossover clinical trial
CONCLUSION: It is concluded that a strength training session can potentially improve or maintain the acute low back pain and disability scale without causing an increase in low back pain symptoms. Furthermore, it can promote a high level of enjoyment, regardless of whether it is conducted in person or remotely. Health education strategies, such as… →
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50+ Model Context Protocol (MCP) Servers Worth Exploring
«`html 50+ Model Context Protocol (MCP) Servers Worth Exploring What is the Model Context Protocol (MCP)? The Model Context Protocol (MCP), introduced by Anthropic in November 2024, establishes a standardized, secure interface for AI models to interact with external tools—such as code repositories, databases, files, and web services—through a JSON-RPC 2.0-based protocol. The MCP protocol… →
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Effect of adding fenofibrate versus curcumin to glimepiride in patients with type 2 diabetes: a randomized controlled trial
CONCLUSION: Both fenofibrate and curcumin are effective at decreasing lipid profiles and improving inflammatory markers in patients with type 2 diabetes. Fenofibrate might have a superior effect in reducing waist circumference, decreasing fetuin-A, and increasing sirtuin 1. →
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Treatment with orforglipron, an oral glucagon like peptide-1 receptor agonist, is associated with improvements of CV risk biomarkers in participants with type 2 diabetes or obesity without diabetes
CONCLUSION: Orforglipron treatment was associated with beneficial changes in CV risk markers in participants with T2D and in participants with overweight/obesity without T2D. (Clinicaltrials.gov: NCT05048719, NCT05051579). →
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Study protocol for the Outcomes Post-Treatment: Impact on Motor Impairment of Sleep Efficiency in Spinal Cord Injury (OPTIMISE SCI) — a randomised controlled trial
INTRODUCTION: Spinal cord injury (SCI) has been linked to increased frequencies of sleep-related breathing disorders (SRBDs) (≤50% after paraplegia and ≤90% following tetraplegia). However, SRBDs have been under-recognised and undertreated among individuals with SCI. The OPTIMISE SCI (Outcomes Post Treatment: Impact on Motor Impairment of Sleep Efficiency in SCI) is an ongoing phase 3 clinical… →
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Glucocorticoid treatment in early rheumatoid arthritis is independently associated with increased PCSK9 levels: data from a randomised controlled trial
CONCLUSION: Glucocorticoid treatment was associated with increased PCSK9 levels after 24 weeks. When compared with the bDMARD treatments, these increases were more pronounced in rheumatoid factor, anticitrullinated protein antibody and antinuclear antibody-positive patients. Our data provide a potential mechanistic link between glucocorticoid treatment and cardiovascular disease. →
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How to Enable Function Calling in Mistral Agents Using the Standard JSON Schema Format
«`html How to Enable Function Calling in Mistral Agents Using the Standard JSON Schema Format In this tutorial, we will demonstrate how to enable function calling in Mistral Agents using the standard JSON schema format. By defining your function’s input parameters with a clear schema, you can make your custom tools seamlessly callable by the… →
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Meet BioReason: The World’s First Reasoning Model in Biology that Enables AI to Reason about Genomics like a Biology Expert
Meet BioReason: The World’s First Reasoning Model in Biology that Enables AI to Reason about Genomics like a Biology Expert BioReason addresses a significant challenge in utilizing AI for genomics: the need for interpretable, step-by-step reasoning from complex DNA data. While DNA foundation models have shown proficiency in learning diverse sequence patterns for tasks like… →