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Executive function in alcohol use disorder with low psychiatric comorbidity: Comparison with a non-clinical sample and predictive value for treatment outcome
CONCLUSIONS: EFs were not impaired and were not a clinically relevant predictor of treatment outcomes in this population with AUD. Future research on EF as a predictor in AUD treatment, needs to corroborate the present findings, and include other populations, e.g., with different socio-economic backgrounds and by including other methodologies for measuring EF. →
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Document Intelligence with Granite Vision and Docling – OpenCV Live! 225
Pengyuan Li of IBM Research returns to OpenCV Live, following his August 2025 appearance where he introduced Granite Vision, IBM’s lightweight open vision-language model built for enterprise document understanding. This time the focus shifts from the model to the workflow: how Granite Vision pairs with Docling, IBM’s open-source document conversion toolkit, to turn PDFs, scans,… →
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Circulating tumour DNA to guide rechallenge with cetuximab plus irinotecan in RAS/BRAF wild-type metastatic colorectal cancer: A nonrandomised clinical trial
CONCLUSIONS: These findings suggest that ctDNA-guided rechallenge with cetuximab plus irinotecan may offer benefit in RAS/BRAF WT mCRC, with STI potentially informing patient selection. Nevertheless, further validation in larger randomised trials is warranted. →
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Effects of Esketamine on Postoperative Hospital Anxiety and Depression Scale Scores in Patients Undergoing Laparoscopic Radical Resection for Colorectal Cancer
CONCLUSIONS: Esketamine given during induction and in PCIA reduced early-stage postoperative HADS scores and improved patient satisfaction in colorectal cancer patients. →
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Monitoring of breathing effort through pressure time product measurement using airway occlusion pressure (PTPPOCC study)
CONCLUSIONS: The PTP(POCC) index showed good performance for identifying extremes of respiratory effort in mechanically ventilated patients. Despite limited individual agreement, its strong association and high specificity may make it a useful tool for confirming very low or excessively high inspiratory effort and for identifying patients at risk of over or under assistance. →
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When AI Disruption Never Ends
Phil Bliss/theispot.com A vice president of product opens her laptop on a Monday morning to find that the AI model her team had worked with for the past six weeks to build a customer workflow has been leapfrogged by a cheaper, faster alternative. Again. Her Slack feed is blowing up with links to the announcement.… →
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Development and Crossover Evaluation of an Artificial Intelligence-Assisted System for Solid Pancreatic Lesion Detection and Pancreatic Parenchyma Recognition in Endoscopic Ultrasonography (With Video)
CONCLUSIONS: AI assistance improved SPL detection among novice endosonographers. For PP recognition, sensitivity increased without reaching statistical superiority, whereas specificity met the predefined noninferiority criterion. These findings support a potential adjunctive role for AI in EUS interpretation. →
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Effect of blueberry consumption on regulatory lymphocyte phenotypes and NK cell functional activity in middle-aged and older adults with overweight or obesity: a randomized controlled trial
CONCLUSION: Overall, blueberry consumption did not substantially modify systemic cellular immune biomarkers in adults with overweight and obesity. Exploratory findings suggest potential benefits in symptom-based outcomes and highlight adiposity as an important determinant of immune variability. →
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Mobile cone-beam computed tomography combined with electromagnetic navigation bronchoscopy for the diagnosis of peripheral pulmonary nodules
CONCLUSION: mCBCT-guided navigation correction improved the tool-lesion relationship and provided incremental clinical value beyond conventional ENB, particularly for smaller lesions and those without a CT bronchus sign, while maintaining an acceptable safety profile. →
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Near and distance vergence facility provides complementary clinical information in concussion-related convergence insufficiency
CONCLUSIONS: Near and distance vergence facility testing provided complementary rather than interchangeable clinical information in adolescents and young adults with concussion-related convergence insufficiency. Both measures improved following vergence/accommodative therapy, supporting consideration of both testing distances in clinical assessment. →