CONCLUSIONS: Standard intubation produced progressive microbial convergence between airway compartments, while the VT system did not. The findings provide biological plausibility for previously reported VAP reductions with the VT system and show that microbiota sampling can detect device-related differences in airway community structure, warranting further investigation as an endpoint for evaluating airway devices. →

CONCLUSION: For post-operative analgesia after lower limb fracture surgery, oliceridine provides analgesic efficacy comparable to hydromorphone. Observations suggest a potential for a lower incidence of PONV with oliceridine, which may offer a favorable opioid option within multimodal analgesic regimens for this population. →

CONCLUSION: Over the 6 months after endovascular treatment accessory to standard care for PTS, both PTS severity measured by the Villalta score and QoL measured by CIVIQ-20 improved. However, greater PTS severity and female sex were independently associated with worse QoL outcomes. →

CONCLUSION: This exploratory study found a suggestion of less postoperative fatigue in the intervention group. Further studies are needed to define the role of unsupervised moderate exercise, if any, before and after surgery in regard to postoperative fatigue in patients with colorectal cancer. →

INTRODUCTION: Language and communication difficulties are common across a range of dementias including primary progressive aphasia (PPA). Better Conversations with PPA (BCPPA) is a co-designed communication partner training intervention that aims to improve the experience of conversations for a person with communication difficulties. An NHS-based pilot study of face-to-face BCPPA demonstrated positive outcomes but also… →

CONCLUSIONS: This study will provide evidence on whether a combination of GET and CBT is feasible and acceptable for the treatment of fatigue in patients with BC in Singapore. It supports the refinement of evidence-based fatigue management guidelines and improvements in BC survivorship care. →

CONCLUSION: CBT-based journaling is an effective and scalable intervention for improving emotional responses and reducing irrational beliefs related to clothing styles. Its efficacy highlights the potential for broad application in mental health promotion, particularly in appearance-sensitive contexts among adolescents and young adults. →

CONCLUSIONS AND RELEVANCE: The health coaching intervention combined with self-measured BP monitoring significantly increased health care engagement and BP control by 12 months post partum. These findings support health coaching as an effective strategy for reducing long-term uncontrolled hypertension among patients with HDP. →

CONCLUSIONS: CAD/CAM-fabricated NCOs and HCOs showed favorable short-term clinical performance in selected MIH-affected FPMs up to the 12-month follow-up. Preliminary 18-month findings should be interpreted with caution, and longer-term follow-up of the complete cohort is required to determine comparative durability. →

CONCLUSION: Ranquilon 1 mg tablets at 6 mg/day demonstrate greater efficacy than Afobazol 10 mg tablets at 30 mg/day in alleviating anxiety associated with neurasthenia and adjustment disorders. The safety profile of Ranquilon is favorable and comparable to that of Afobazol. →