CONCLUSIONS: On average, RTW-PIA did not significantly improve SRTW or secondary outcomes. Employees without a recognized disability degree, with low social support at work, or with diagnosed recurrent depressive disorders might benefit from RTW-PIA. These hypotheses need to be tested in independent samples. Further research should also focus on the implementation of RTW-PIA. →

Exacerbations of chronic obstructive pulmonary disease (COPD) are a leading cause of morbidity, mortality, and healthcare burden. While standard bronchodilator therapy alleviates airway obstruction, its efficacy is often limited. This study evaluated nebulized furosemide, which has bronchodilatory and anti-inflammatory effects, as an adjunct to salbutamol-ipratropium in hospitalized COPD patients. Ninety‑two patients with exacerbated COPD were… →

CONCLUSIONS: Denecimig maintained low ABRs over 52 weeks, was well tolerated, and improved patient-reported outcomes in adolescents and adults with HA with or without inhibitors. →

CONCLUSIONS: BESS was associated with significantly lower wound dehiscence rates compared with MSS in patients undergoing single-level lumbar decompression or discectomy. Drainage volume ≥ 100 mL may serve as a clinical indicator for enhanced wound surveillance in MSS patients. These hypothesis-generating findings warrant validation in independent cohorts. →

Responses to physical activity interventions vary among adults with arthritis, and baseline functional limitations may affect increases in walking. To determine whether baseline physical function moderated changes in accelerometer-measured steps/day after a telephone-delivered Walk With Ease (WWE-T) intervention. This secondary analysis included 267 adults from a randomized trial of WWE-T versus wait-list control. Baseline function… →

CONCLUSION: In this post-hoc analysis of the SODa-BIC trial, the use of hierarchical composite outcomes did not alter the neutral overall interpretation of the original trial. However, this analysis provides additional insight into the relative contribution of individual components of the primary outcome. →

CONCLUSION: Immediate referral to a cessation clinic was the factor most strongly associated with one-year abstinence, together with absence of comorbidity and, tentatively, repeated hospitalisation; greater disease severity was associated with quitting only in unadjusted comparisons. These exploratory findings support structured cessation pathways in routine COPD care. →