CONCLUSIONS: Overall, the findings indicate that Alba may be beneficial in reducing mental health symptoms among bereaved adolescents and highlight its potential as a safe, acceptable, and scalable mHealth intervention. →

CONCLUSION: Intranasal oxytocin was well tolerated but did not significantly reduce drinking or AUD-related outcomes. Higher doses, longer treatment duration, or larger trials may be required to identify responsive subgroups and determine oxytocin’s efficacy in AUD. →

INTRODUCTION: Of individuals with mild-to-moderate multiple sclerosis (MS), 56% report falling at least once during a 3-month period. Several fall risk factors have been identified, but the issue is complex, with interactions between triggering factors and preceding activities and events. There is a lack of studies explicitly evaluating fall prevention strategies given as counselling over… →

CONCLUSIONS: Early oral acetaminophen treatment in very preterm infants with hsPDA aged 4-7 days reduces the rate of persistent hsPDA at 14-17 days and demonstrates a favorable safety profile compared with expectant management, but does not affect hsPDA persistence at discharge or 36 weeks of corrected gestational age or the rate of moderate to severe… →

CONCLUSIONS: In this phase 3 trial involving patients with standard-risk newly diagnosed multiple myeloma who were not undergoing up-front autologous stem-cell transplantation, indefinite-duration maintenance therapy after induction therapy did not result in significantly longer overall survival than fixed-duration maintenance therapy. (Funded by the National Cancer Institute of the National Institutes of Health and Amgen; ENDURANCE… →

Trigger finger (TF) is stenosing tenosynovitis causing pain and impaired hand function. To compare extracorporeal shock wave therapy (ESWT) and high-intensity laser therapy (HILT) as adjuncts to home exercise in TF. In this three-arm randomized controlled trial, patients were allocated to ESWT, HILT, or home exercise alone. Active modalities were applied for 3 weeks (nine… →

CONCLUSION: Methodological variability significantly impacts reported adherence rates. While no single «gold standard» exists, integrating brief self-reported scales with objective metrics is feasible and provides a more comprehensive and clinically informative assessment of medication use. This multi-method approach is essential for identifying at-risk patients and tailoring adherence-support interventions in oncology. →

Background/Objectives: Malnutrition affects 20-71% of patients with head and neck cancer (HNC), owing to tumor location, treatment-induced toxicities, and systemic inflammation. Enteral nutrition is preferred when oral intake is inadequate, yet standard powdered formulas require labor-intensive reconstitution and carry a contamination risk. PSU Blen, a ready-to-drink chicken-protein-based polymeric formula, was developed to address these limitations.… →

Background: Selenium is an essential trace element for humans that plays a key role in glucose homeostasis and hepatic function. Biofortification is a sustainable agricultural technique able to increase micronutrients and reduce pesticides in crops. Purpose: The present study aimed to examine whether the consumption of strawberries biofortified with selenium in a healthy population for… →

Background/Objectives: Given the rising prevalence of overweight and obesity in pediatric populations, identifying effective nutritional interventions for metabolic management is crucial. Beyond their nutritional value, soy and lupin proteins are recognized for their bioactive properties. We formulated two protein-enriched functional beverages and evaluated their impact on the metabolic profile and gut microbiota of adolescent boys… →