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Standardized Berry Extract Improves Selected Visual Function Outcomes in Presbyopia: A Randomized, Double-Blind, Placebo-Controlled Crossover Trial with Exploratory Biomarker Analysis
CONCLUSIONS: Overall, short-term AKB supplementation was associated with modest, exploratory changes in selected functional and systemic biomarker outcomes, but larger and longer-term studies are needed to confirm clinical relevance and clarify underlying mechanisms. →
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Minimally Cooked Potato Improved Glycemic Response Across Two Meals and Insulin Sensitivity of Rice-Potato Mixed Meals: A Randomized Controlled Acute Trial
Objectives: This study aimed to investigate the possible association among texture, oral processing and starch digestive characteristics of hard-cooked (HP) and soft-cooked (SP) potato samples, as well as their acute postprandial glycemic and insulinemic response, when co-ingested with rice in a meal. Methods: HP and SP replaced one-third of rice carbohydrates. Postprandial glycemic and insulinemic… →
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Implementation Lessons and Policy Implications of Same-Day Antiretroviral Therapy Initiation: Insights from the ART Same-Day Counselling and Initiation (ASCI) SOP in South Africa
Same-day antiretroviral therapy (ART) initiation (SDI) is globally recommended to improve ART uptake. However, retention in care and viral suppression in South Africa remain suboptimal. This study evaluated the experiences of healthcare providers, patients, and community stakeholders in implementing the ART Same-day Counselling and Initiation (ASCI) Standard Operating Procedure (SOP), focusing on facilitators, barriers, and… →
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Why We Should Worry About Stagflation
It’s a word that keeps economists up at night: “stagflation.” The ugly combination of inflation and recession maximizes the pain for consumers and businesses while also leaving policymakers without their usual levers for steering the economy. It creates a crisis that’s more than the sum of its parts, says Kellogg economist Phillip Braun. “Stagflation is… →
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Long-Term Outcomes of Concurrent Chemoradiotherapy With S-1 in Older Patients With Esophageal Cancer: A Secondary Analysis of a Randomized Clinical Trial
CONCLUSIONS AND RELEVANCE: In this secondary analysis of a randomized clinical trial, long-term results showed that CCRT with S-1 was associated with a sustained survival benefit compared with RT alone, without increased noncancer-related mortality. This finding supports CCRT with S-1 as the preferred regimen for patients aged 70 to 85 years with EC. →
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How Morningstar’s CEO Drives Relentless Execution
Aleksandar Savic Many investors rely on Morningstar for independent financial analysis and insights, but few people are familiar with the company behind the ratings. From Morningstar’s origins rating mutual funds, the company has expanded its product line, customer base, and global footprint and realized a tenfold increase in revenues and profits between 2005 and 2025.… →
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Eptinezumab With Patient Education for Chronic Migraine and Medication-Overuse Headache: The Randomized, Placebo-Controlled RESOLUTION Trial
BACKGROUND AND OBJECTIVES: Medication-overuse headache (MOH) commonly co-occurs with and complicates chronic migraine (CM). This trial evaluated efficacy and safety of eptinezumab, an anti-calcitonin gene-related peptide monoclonal antibody for migraine prevention-combined with a standardized brief educational intervention (BEI)-in adults with CM and MOH. We report results from the 12-week placebo-controlled period, of which weeks 1-4… →
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Continuous vs Intermittent Postoperative Vital Sign Monitoring: A Cluster Randomized Crossover Trial
CONCLUSIONS AND RELEVANCE: In this cluster randomized crossover trial of continuous compared with intermittent vital sign monitoring, continuous monitoring reduced the duration of desaturation in patients recovering from noncardiac surgery on general hospital wards. Reducing the duration of vital sign abnormalities may decrease the risk of more serious complications, and robust patient-centric outcomes trials seem… →
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The Effect of Breast Cancer and Breast Self-Examination Health Education on Awareness, Beliefs, and Practices of Female Students at the Faculty of Health Sciences of a University in Somalia
CONCLUSION: HBM-based breast health education improved students’ knowledge, awareness, and BSE practice. Although BSE is not a screening tool, it is an essential awareness method in settings with limited access to diagnostic services. →
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Phage therapy of purulent wounds: comparative clinical cytomorphological and microbiological analysis of effectiveness
CONCLUSION: The principles of purulent wounds treatment in our country are based on the method of active surgical treatment developed in the Department of Wounds and Wound Infections of the Vishnevsky Institute of Surgery (now the Vishnevsky National Research Medical Center of Surgery of the Ministry of Health of the Russian Federation). The results of… →
