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EQ-5D vision bolt-on in macular degeneration: associations with visual measures and effect on utility differences and cost-effectiveness of stereotactic radiotherapy
CONCLUSIONS: Resource use data from the trial and routine follow-up could be used for future economic models. The vision bolt-on captured quality of life differences between participants but may not be sufficiently responsive to visual acuity decline in trials where only one eye is treated. →
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Effectiveness of acceptance and commitment therapy on sexual function in women infected with human papillomavirus: a randomized controlled trial
CONCLUSION: Group Acceptance and Commitment Therapy effectively enhances sexual function and overall quality of life in women with HPV, suggesting its integration into supportive healthcare interventions. →
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The Global Scaling Gap: Why Strategic Clarity Is Crucial in the Age of AI
Michael Glenwood Gibbs/theispot.com Digital platforms and generative AI have lowered the barriers to accessing global talent, capital, and knowledge for companies everywhere while making it possible to reach customers across languages and cultures. Research my colleagues and I have conducted suggests that such tools make it easier for entrepreneurs to serve global markets and for… →
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How to Drive AI Adoption: Lessons From 21 GTM Leaders
What’s your ideal day to get this newsletter? We’ve been testing different days! So far Fridays, Sundays, and Mondays are leading the pack. Let us know if you have a preference! Brought to you by Primer – Primer unlocks B2C ad channels for B2B marketers with precision targeting and next-gen measurement. There are two ways… →
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Hydrocodone vs Oxycodone and Postoperative Pain and Opioid Use in Joint Arthroplasty
CONCLUSIONS AND RELEVANCE: In this cohort study of CYP2D6 NMs undergoing joint arthroplasty, within multimodal analgesia, hydrocodone provided comparable pain control to oxycodone with significantly lower opioid exposure, supporting its use as a viable and possibly preferable analgesic option. →
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Rethinking Drone Autonomy in GPS-Denied Environments – OpenCV Live Ep. 217
Autonomous drones only fly as well as they can figure out where they are. Drop one into a forest, a dense city, or a disaster zone, and that gets a lot harder — the signals they normally lean on just aren’t there. This week we get into HUNT, a navigation approach built for exactly the… →
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Differences in Posterior Ocular Morphology Following Red Light Therapy Versus 0.01% Atropine for Myopia Control: A Randomized Controlled Trial Analysis
CONCLUSIONS: Over 12 months, RLRL showed broader macular flattening and more region-specific MOSH changes compared with 0.01% atropine in this cohort. However, the underlying mechanisms and the independent contribution of myopic progression to these morphological differences require further study. →
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Fractional Flow Reserve-Guided Renal Artery Stenting in Renovascular Hypertension: 1-Year Results of the FAIR Study
CONCLUSIONS: At the 1-year follow-up, FFR-guided renal artery stenting reduced stent use without loss of blood pressure control or renal safety compared with angiography guidance. →
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Effect of Sublingual Nitroglycerin on Absolute Coronary Blood Flow: A Randomized Double-Blind Placebo-Controlled Mechanistic Study
CONCLUSIONS: Sublingual NTG induced a significant decrease in left ventricular preload and afterload, resulting in a marked decrease in myocardial work. This was associated with a significant and adaptive decrease in absolute coronary blood flow. →
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How GenAI Can and Can’t Help Manage Customer Insights
Carolyn Geason-Beissel/MIT SMR | Getty Images To understand their customers and markets, a growing number of customer-oriented companies are using generative AI tools, alongside the language and reasoning capabilities of popular large language models (LLMs), to access and analyze their own internal content. These hybrid knowledge approaches, which typically employ a technique called retrieval-augmented generation… →