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  • Combining Cognitive Training and Brain Stimulation: A Novel Approach to Address Disordered Eating and Antipsychotic-Induced Weight Gain in People With Severe Mental Illness

    26 октября, 2026

    CONCLUSION: The initiation of antipsychotic therapy is a critical clinical window for early intervention to mitigate the long-term metabolic and psychiatric consequences of antipsychotic-induced weight gain. Combining ABMT + tDCS is acceptable and may help reduce binge eating in individuals on antipsychotics, with a potential synergistic effect between cognitive training and brain stimulation. A confirmatory… →

    Clinical Trials
  • Four weeks of isometric handgrip training results in lower awake ambulatory blood pressure compared with control: a randomized clinical trial

    26 октября, 2026

    We compared the effects of upper-limb (handgrip) and lower-limb (knee extension) isometric training on ambulatory blood pressure in individuals with controlled hypertension. In this randomized controlled trial, 67 adults receiving antihypertensive medication were allocated to a control group (CG, n = 22), small muscle mass isometric training (SMM, handgrip; n = 22), or large muscle… →

    Clinical Trials
  • Indirect moxibustion therapy improves insomnia and associated symptoms in patients with schizophrenia

    26 октября, 2026

    CONCLUSIONS: Adjunctive Indirect Moxibustion led to statistically significant and clinically meaningful improvements in sleep quality and quality of life compared to sham procedure in this patient population over an 8-week period. These preliminary findings suggest IM is a promising adjunctive therapy. Further multicenter, long-term trials with expanded outcome indicators are required to validate its generalizability… →

    Clinical Trials
  • Parental perspectives on clinician guidance in value-laden NICU conversations: a qualitative study

    26 октября, 2026

    CONCLUSIONS: Parents facing complex medical decisions value both high-quality information and empathetic and honest communication. While they generally retain decision ownership, preferences regarding clinician guidance vary, suggesting that clinicians should actively explore how much direction parents want and tailor their communication accordingly. →

    Clinical Trials
  • Spherical Video-Based Virtual Reality Training for Nurses’ Delirium Care Competence: A Randomized Controlled Trial With Qualitative Evaluation

    25 октября, 2026

    CONCLUSION: SVVR training was associated with greater and sustained gains in delirium care knowledge and greater immediate gains in confidence compared with noninteractive video education. Confidence appeared to be further reinforced by subsequent clinical exposure. →

    Clinical Trials
  • Dietitian-Led Synchronous and Asynchronous Tele-Nutrition in Children With Spinal Muscular Atrophy: A Three-Arm Randomized Controlled Trial

    25 октября, 2026

    CONCLUSION: Dietitian-led tele-nutrition was associated with greater reductions in caregiver feeding-related problems and, to a smaller extent, child nutrition-related problems than control. The two delivery models did not differ for NPS or CFPS; the TFPS comparison was sensitive to adjustment for baseline values. Because the primary outcomes are investigator-developed measures without established thresholds for clinically… →

    Clinical Trials
  • Association Between Ellipsoid Zone Area and Fixation Stability in Macular Telangiectasia Type 2

    25 октября, 2026

    CONCLUSIONS: Greater EZ area loss is associated with poorer fixation stability in MacTel. An EZ area loss threshold of ∼1 mm² may serve as an exploratory marker of fixation instability risk, though this threshold requires independent validation. →

    Clinical Trials
  • Hematological and biochemical responses to three doses of caffeine during the CrossFit workout: a randomized, double-blind, crossover trial

    25 октября, 2026

    CONCLUSIONS: These findings suggest that acute CAF ingestion selectively influences post-exercise glucose responses during the CrossFit^(®) workout, whereas hematological variables and most biochemical markers remain unaffected. Significant post-exercise glucose elevations were observed following the 6 and 9 mg(CAF)/kg(BM) conditions compared with baseline and PLA visits, while serum mineral concentrations remained largely stable across treatments. →

    Clinical Trials
  • Performance of HPV testing and liquid-based cytology after negative colposcopy in women with ASC-H, HSIL or AGC cytology

    25 октября, 2026

    CONCLUSION: A substantial proportion of HSIL+ lesions persist despite negative colposcopy. HPV testing effectively rules out disease, and combining with LBC enhances diagnostic safety and accuracy. This dual-test approach offers a practical strategy to guide management and reduce diagnostic failures in women with ASC-H or worse cytology. →

    Clinical Trials
  • Association between nutritional status and health perception among participants of the Academida da Saúde Program: a cross-sectional study, Belo Horizonte, 2013-2014

    25 октября, 2026

    CONCLUSION: Obesity was associated with poorer health perception among participants in the Health Academy Program. →

    Clinical Trials
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