CONCLUSIONS: The proximal aorta shows a multisegment architecture in which organization across patients is stronger than within-patient coordination of change. Network findings complement, but do not replace, serial measurement of individual aortic levels, and their prognostic value requires independent validation. →

BACKGROUND: A practical application of artificial intelligence (AI) in healthcare is to generate artificial datasets that capture the characteristics of a real source dataset without exposing protected health information. This approach is particularly relevant to research settings where recruitment and long-term follow-up are barriers to generating robust clinical evidence. →

CONCLUSIONS: These findings suggest that co-designed SMS text messaging-based programs show promise and may represent a feasible strategy for oral health behavior change. However, larger-scale and longer-term studies are needed to confirm sustained effectiveness using clinical outcomes. Future research should also explore ways mobile health can be scaled and cost-effectively embedded into comprehensive, interdisciplinary primary… →

CONCLUSIONS: Post-PCI μQFR distributions were similar between treatment groups, but lower values were associated with higher 5-year adverse event risk without significant treatment interaction. Its limited binary discrimination supports use as a continuous metric for post-PCI physiological risk stratification. (ClinicalTrials.gov: NCT03656848). →

CONCLUSIONS AND RELEVANCE: In this study, satisfaction with the mobile market was high, but the mobile market did not improve diet quality or most outcomes examined. The mobile market was associated with a meaningful sodium reduction that could improve population-level health. →

Background Contrast-enhanced mammography (CEM) is increasingly used in breast cancer diagnostics; however, randomized trials assessing the added value of CEM in preoperative staging of breast cancer beyond digital mammography, digital breast tomosynthesis, and US are lacking. Purpose To assess the added value of CEM for preoperative breast cancer staging in a randomized controlled trial. Materials… →

CONCLUSIONS: Vitamin D 3 supplementation significantly improved glycaemic control and insulin sensitivity in pre-diabetic adults, supporting its role as a safe, cost-effective adjunct to lifestyle modification in pre-diabetes management. →

CONCLUSIONS: The results reveal significant plasticity in the visual system in DR and suggest that contrast detection training may extend to motion perception tasks. Our study provides additional support for VPL as a potential treatment for DR. →