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  • Robot-assisted rehabilitation therapy for adhesive capsulitis: A pilot randomized controlled trial on clinical and patient-reported outcomes

    22 августа, 2026

    CONCLUSION: This pilot study establishes the feasibility and tolerability of RART in patients with adhesive capsulitis and provides preliminary, exploratory evidence of beneficial effects on pain and range of motion. Given the underpowered final sample size (post hoc power: 68%-70%), these findings should be interpreted with caution and require confirmation in adequately powered future trials. →

    Clinical Trials
  • Effect of Remote Vital Signs Monitoring in People Receiving Long-Term Oxygen Therapy: Protocol for a Randomized Controlled Trial

    22 августа, 2026

    CONCLUSIONS: This study will provide relevant evidence on the effect of remote monitoring in individuals receiving LTOT on HRQoL, dyspnea, health status, anxiety and depression, and engagement with data entry through a mobile app. →

    Clinical Trials
  • Efficacy of Mulligan Mobilization, Maitland Mobilization, High-Velocity Thrust, and Muscle Energy Technique for Pain, Disability, and Center-of-Gravity Displacement in Patients With Sacroiliac Joint Dysfunction: Protocol for a Randomized Controlled Trial

    21 августа, 2026

    CONCLUSIONS: This protocol is designed to provide robust comparative data on manual therapy approaches for SIJ dysfunction. Findings may guide physiotherapy practice by informing evidence-based recommendations for optimal management strategies. →

    Clinical Trials
  • Association of Supportive Text Messaging With Health Service Utilization Costs Following Psychiatric Admission: Secondary Economic Analysis of a Stepped-Wedge Cluster Randomized Trial

    21 августа, 2026

    CONCLUSIONS: SMS was associated with significant reductions in hospital care and total health care utilization costs during the 6-month postdischarge period compared with TAU. These findings support the integration of cost-effective and scalable digital interventions into routine psychiatric discharge pathways to help improve system efficiency in publicly funded health systems. →

    Clinical Trials
  • Portable Ultra-Low-Field MRI in Outpatient Neurology: An Examination of Clinical Performance and Patient Experience

    21 августа, 2026

    CONCLUSIONS: In outpatient neurology practices, pMRI images demonstrated high clinical concordance with sMRI for identifying the presence or absence of structural brain abnormalities and were strongly preferred by patients. These findings support the use of pMRI as a practical point-of-care imaging tool for neurology patients, enabling timely access to structural neuroimaging during the clinical encounter. →

    Clinical Trials
  • BIOCARD framework: integrating fecal bile acids, lipids, and metabolites to assess response to a cardiovascular health intervention

    21 августа, 2026

    Cardiovascular disease (CVD) remains a leading cause of morbidity and mortality, particularly in under-resourced populations. Although nutritional interventions are important for CVD prevention, their outcomes are commonly evaluated using conventional clinical and behavioral indicators, which may not fully capture early molecular responses. In this study, we developed the BIOCARD framework, an exploratory fecal multi-omics platform… →

    Clinical Trials
  • Comparative effectiveness of levofloxacin versus third-generation cephalosporins and predictors of treatment outcomes in upper respiratory tract scleroma: a tertiary center experience

    21 августа, 2026

    Upper respiratory tract scleroma is a chronic granulomatous disease that primarily affects the nose but may involve any part of the upper respiratory tract. The mainstay of treatment is prolonged antibiotic therapy. This prospective comparative study included 90 adults with upper respiratory tract scleroma treated at Minia University Hospital, Egypt, between September 2024 and August… →

    Clinical Trials
  • Exploring possibilities towards PeRsonalIsed MEdicine in Rheumatoid Arthritis (PRIMERA): tailored modifications to standard treat-to-target management-a multicentre, randomised, open-label trial

    21 августа, 2026

    CONCLUSION: Modifying the standard treat-to-target strategy, by stratifying the initial DMARD according to autoantibody status combined with rapidly intensifying therapy based on early treatment response, did not result in superior clinical outcomes. →

    Clinical Trials
  • Algorithms Trap Us in the Familiar. Can They Also Spark Breakthroughs?

    21 августа, 2026

    Gary Waters/Ikon Images Algorithmic tools promise to democratize access to knowledge and thus spark creativity and innovation, but research we conducted revealed a hidden risk: Those tools may be silently narrowing organizations’ creative potential by suppressing the value of expertise. The fault lies not with the experts but with the hidden architecture of the tools… →

    Management
  • Chlorhexidine Gluconate as a Conducting Medium Is Noninferior to Ultrasound Gel in Ultrasound Image Quality: A Blinded, Randomized Comparative Study

    20 августа, 2026

    CONCLUSIONS: The commonly used skin antiseptic chlorhexidine gluconate with isopropyl alcohol demonstrated noninferior image quality compared with ultrasound gel and may represent a more economical alternative for ultrasound-guided interventions, with the potential to reduce infectious complications. →

    Clinical Trials
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