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  • Safety and Feasibility of Long-Term High-Intensity Interval Training With and Without Peer Support in Cancer Survivors

    8 февраля, 2026

    Despite the benefits of physical activity and exercise, including high-intensity interval training (HIIT), few cancer survivors meet the exercise oncology guidelines. Emerging evidence suggests peer support (i.e., assistance from individuals with lived experiences trained in behavior change techniques) may improve exercise adherence, yet its long-term safety and feasibility remain unclear. This study evaluates the safety… →

    Clinical Trials
  • Histopathological Findings of Appendix Specimens in Quiescent Ulcerative Colitis: Correlations With Clinical Outcomes in the ACCURE Trial

    7 февраля, 2026

    CONCLUSION: Active appendiceal inflammation is prevalent in quiescent UC and showed a trend toward association with relapse risk. Although the benefit of appendicectomy in this group cannot be confirmed on these data alone, the finding might be clinically relevant as relapse rates are significantly reduced in the appendicectomy group. →

    Clinical Trials
  • Safety and Preliminary Clinical Effects of a Herbal Balance Solution in Mild-To-Moderate Acne Vulgaris: An Open-Label, Single-Arm Pilot Study

    7 февраля, 2026

    CONCLUSION: In this open-label pilot study, use of Herbal Balance Solution was associated with short-term improvements in acne-related clinical parameters and skin barrier function and was well tolerated in patients with mild-to-moderate acne vulgaris. These preliminary findings warrant confirmation in randomized, vehicle-controlled clinical trials. →

    Clinical Trials
  • Comparison of Disorder-Specific Group CBT and Generic Group CBT in Treating Adolescents with Social Anxiety Disorder: A Randomized Controlled Trial

    7 февраля, 2026

    Social anxiety disorder is one of the most common disorders in adolescence. It is associated with severe distress, negative long-term consequences, and chronicity. Cognitive behavioral treatment (CBT) is the recommended treatment for social anxiety disorder. However, adolescents with social anxiety disorder consistently show poorer outcomes than any other anxiety disorder. The aim of the study… →

    Clinical Trials
  • Perceptions of best practice, pain science and structure-focused education for rotator cuff-related shoulder pain: a content analysis of qualitative data from a randomised experiment

    7 февраля, 2026

    CONCLUSION: Participants with rotator cuff-related shoulder pain expressed generally similar emotional responses across groups, with small differences in treatment preferences favouring self-management in the best practice education groups compared with those who received structure-focused education. Those in the best practice education also less frequently reported needing potentially unnecessary treatments (eg, imaging, injections and surgery). →

    Clinical Trials
  • Effect of race and sex on lupus diagnosis in primary care: A randomized factorial survey study

    7 февраля, 2026

    CONCLUSION: A patient’s race and sex may influence diagnostic accuracy and clinical decision-making for SLE in primary care. The observed variation in diagnostic accuracy, which aligns with the descriptive epidemiology of SLE, highlights the need for targeted interventions to ensure equitable diagnostic processes. →

    Clinical Trials
  • Randomized controlled trial on the effects of different antibiotic regimens in preterm premature rupture of membranes after 34 weeks

    7 февраля, 2026

    CONCLUSION: The 2 different antibiotic regimens administered to pregnant women diagnosed with PPROM after the 34th week of gestation demonstrated similar clinical effects in terms of maternal and neonatal outcomes. Although the differences in NICU stay duration and the number of chorioamnionitis cases were not statistically significant, we believe that these findings could reach significance… →

    Clinical Trials
  • How to Price Your AI Product: A Practical Guide for Early-Stage Founders

    7 февраля, 2026

    Pricing is one of the hardest decisions founders make. And in the AI era, it’s become one of the most critical to get right. Costs move quickly, usage patterns shift unpredictably, and buyers are suddenly much more sensitive to how value gets delivered. What used to be a simple question of “What should we charge?”… →

    AI Sales
  • Feasibility of an Indigenous Food Is Medicine Program for Patients With Heart Failure in Rural Navajo Nation: The MUTTON-HF Nonrandomized Clinical Trial

    6 февраля, 2026

    CONCLUSIONS AND RELEVANCE: In this nonrandomized clinical trial, the MUTTON-HF intervention incorporating Indigenous recipes and locally sourced Native food was feasible and acceptable for patients with heart failure in rural Navajo Nation. These findings will inform a future randomized clinical trial to evaluate the effectiveness of this intervention to advance Indigenous cardiovascular health and food… →

    Clinical Trials
  • Remimazolam vs. midazolam sedation in upper gastrointestinal endoscopy in adults 65 years: Randomized controlled trial

    6 февраля, 2026

    CONCLUSIONS: In performing upper gastrointestinal endoscopy in older patients, remimazolam can be a good alternative sedative to midazolam, whether used as monotherapy or in combination therapy. →

    Clinical Trials
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