CONCLUSION: In men with ED, orgasmic intensity was progressively lower with increasing ED severity, and treatment with Sildenafil OF improved it substantially, but not exclusively, through improvements in erectile rigidity and maintenance. Orgasmic intensity is a clinically relevant, low-burden measure that may complement erectile assessment in men with ED. →

CONCLUSIONS: Physicians demonstrate substantial automation bias when exposed to erroneous LLM recommendations, even with voluntary consultation and prior AI literacy training. These findings highlight safety risks that require robust validation frameworks and regulatory safeguards before widespread clinical AI deployment. (Funded by the Learning Institute at Lahore University of Management Sciences.). →

CONCLUSIONS: The combined formulation of simethicone and N-acetylcysteine incorporated into a lidocaine ice popsicle improved mucosal visibility compared with a lidocaine ice popsicle alone during unsedated EGD and was associated with improved procedural efficiency. This integrated formulation may provide a practical approach to pre-endoscopic preparation by combining topical anesthesia with mucosal cleansing. Further multicenter studies… →

CONCLUSIONS: Overall, WThE reduced self-reported gastrointestinal symptom burden and improved selected quality-of-life outcomes in adults with persistent gastrointestinal discomfort, supporting Thymus serpyllum as a safe and well-tolerated botanical intervention linked to favorable modulation of the fecal microbiome and enhanced gastrointestinal function. →

CONCLUSION: The initiation of antipsychotic therapy is a critical clinical window for early intervention to mitigate the long-term metabolic and psychiatric consequences of antipsychotic-induced weight gain. Combining ABMT + tDCS is acceptable and may help reduce binge eating in individuals on antipsychotics, with a potential synergistic effect between cognitive training and brain stimulation. A confirmatory… →

We compared the effects of upper-limb (handgrip) and lower-limb (knee extension) isometric training on ambulatory blood pressure in individuals with controlled hypertension. In this randomized controlled trial, 67 adults receiving antihypertensive medication were allocated to a control group (CG, n = 22), small muscle mass isometric training (SMM, handgrip; n = 22), or large muscle… →

CONCLUSIONS: Adjunctive Indirect Moxibustion led to statistically significant and clinically meaningful improvements in sleep quality and quality of life compared to sham procedure in this patient population over an 8-week period. These preliminary findings suggest IM is a promising adjunctive therapy. Further multicenter, long-term trials with expanded outcome indicators are required to validate its generalizability… →

CONCLUSIONS: Parents facing complex medical decisions value both high-quality information and empathetic and honest communication. While they generally retain decision ownership, preferences regarding clinician guidance vary, suggesting that clinicians should actively explore how much direction parents want and tailor their communication accordingly. →