CONCLUSIONS: Tracheobronchial NTM infection is rare but clinically significant, often occurring in the context of disseminated disease with pulmonary involvement. Immunocompromised hosts, particularly those with AIDS or anti-IFN-γ autoantibody syndrome, are highly susceptible. Bronchoscopy typically reveals mass lesions causing luminal stenosis or occlusion. In this cohort, M. colombiense was the most frequently isolated NTM species.… →

Background and Objectives: Hemodialysis patients are characterized by insulin resistance. Cold dialysis (CD), with or without intradialytic exercise training (IET), can be beneficial for overall health in this population. The present study aimed to examine the long-term effect of the combined effect of cold dialysis and intradialytic exercise training on glucose disposal and various health… →

INTRODUCTION: Community-acquired pneumonia (CAP) is common and remains the leading infectious cause of death worldwide. Antibiotics remain the mainstay of treatment, but organisms are often not identified, necessitating empirical treatment. Current treatment guidelines recommend combination therapy with beta-lactams and macrolides or monotherapy with fluoroquinolones for non-severe CAP. However, rising antibiotic resistance and safety concerns have… →

CONCLUSIONS AND RELEVANCE: In this secondary analysis of a randomized clinical trial of patients with esophageal cancer achieving a CCR after nCRT, active surveillance was cost-effective over a 5-year horizon compared with standard surgery. Broader implementation of this strategy among appropriately selected patients would most likely reduce health care costs without compromising health outcomes. →

CONCLUSIONS: This reconstructed-data post hoc analysis suggested exploratory time-dependent patterns in effect estimates without formal evidence of a time-varying treatment effect. Findings are descriptive, hypothesis-generating, and should not be extrapolated to molecularly confirmed HRR-proficient disease. →

CONCLUSION: Although adding toothbrushing to routine chlorhexidine oral care did not produce a statistically significant reduction in VAP incidence or mortality, a consistent trend toward clinical benefit was observed across multiple outcome measures, including lower rates of positive sputum cultures, reduced inotropic support requirements, and fewer new pulmonary infiltrates. These findings highlight the potential value… →

Local pain following orthodontic tooth movement negatively affects patients’ experience and compliance. Pulsed neodymium-doped yttrium-aluminum-garnet (Nd:YAG) laser, based on photobiomodulation therapy (PBMT), can effectively relieve this pain. This study applied pulsed Nd:YAG laser at different frequencies to orthodontic sites and used digital techniques to evaluate differences in pain relief after tooth movement, aiming to screen… →

CONCLUSIONS: In this cohort of hypertensive Black African adults, ECG criteria showed a moderate association with LVMI by echocardiography. Among established ECG criteria, Cornell voltage product-based measures demonstrated the most consistent diagnostic performance. Diagnostic characteristics were strongly influenced by cut-off selection and clinical context, underscoring the need for population-specific evaluation and external validation of ECG… →