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Spot New Tech Skills Emerging From the Workforce
Matt Chinworth Across industries, companies are investing unprecedented sums in reskilling programs to prepare employees to use emerging technologies.1 The programs are typically built around forecasts of which skills, such as data literacy, digital fluency, systems thinking, and adaptability, will matter most. Each year, when the forecasts are updated, training courses — and their related… →
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The effect of integrating pain neuroscience education with stabilization exercises using a flexi-bar on functional disability, pain, and geometry of abdominal and multifidus muscles in patients with chronic non-specific low back pain
CONCLUSION: The combined PNE plus stabilization exercises yielded superior improvements in pain, disability, and muscle geometry compared with stabilization alone. However, the absence of a PNE-only group precludes isolating the educational component’s unique contribution. Iranian Registry of Clinical Trials; prospectively registered (Trial number: IRCT20230505058095N1). →
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A Multilevel Intervention to Identify Individuals for Genetic Testing and Treatment: The IGNITE-TX Pilot Randomized Clinical Trial
CONCLUSIONS AND RELEVANCE: In this pilot randomized clinical trial, IGNITE-TX was feasible to deliver in a community-recruited cohort with structural barriers to care and was associated with higher CGT completion and improved informed decision-making and readiness compared with non-IGNITE-TX arms. These findings support further evaluation of IGNITE-TX as a scalable navigation model for equitable hereditary… →
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Serial Platelet Function-Guided Antiplatelet Modulation After STEMI: A Randomized Pilot Study
BackgroundPlatelet reactivity varies after ST-segment-elevation myocardial infarction (STEMI). We evaluated serial platelet function-guided P2Y12 modulation after a 1-month ticagrelor run-in.MethodsAt month 1, 114 patients were randomized to continued ticagrelor (n=59) or an adenosine diphosphate (ADP)-guided strategy (n=55). Month-1 ADP was the preintervention baseline; months 2, 3, 6, 9, and 12 were analyzed using baseline-adjusted generalized… →
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Post-Intubation Hypotension After Titrated Induction with Ciprofol versus Propofol in Older Adults Undergoing Non-Cardiac Surgery: A Randomized Controlled Trial
CONCLUSION: In this single-center trial of older adults undergoing non-cardiac surgery, ciprofol-based titrated induction was associated with less post-intubation hypotension, lower rescue vasopressor requirement, and less cumulative hypotensive exposure than propofol, without an apparent increase in early adverse recovery outcomes. These findings suggest a favorable hemodynamic profile of ciprofol, which requires confirmation in larger multicenter… →
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Relationship between sociodemographic characteristics at presentation and outcomes of provoked venous thromboembolism in United States children: a secondary analysis of the multinational Kids-duration of therapy for thrombosis trial
CONCLUSION: These findings suggest the need for further studies to determine optimal posttreatment follow-up in this older age group to increase PTS detection rates. We recommend that future collaborative pediatric VTE studies systematically collect social determinants of health variables to better assess their impact on VTE presentation, treatment, and outcomes in children. →
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Enhancing Self Care Among Oral Cancer Survivors Using a Digital Approach: The Empowered Survivor Trial
CONCLUSIONS: The ES enhanced self-efficacy and increased self-care activities. Further examinations of survivorship preparedness and HRQoL in oral and oropharyngeal cancer are warranted. →
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Improving Patient Comfort of Vibratory Anesthetic Devices With a Dampener: A Pilot Study
CONCLUSION: Dampening VAD vibration with a cotton buffer enhances comfort across sensitive sites, with reduced harshness and smoother sensation underlying preference. This simple modification may improve patient experience, encouraging broader VAD adoption. →
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Comparison of Sensory-Adapted and Regular Dental Environments During Professional Oral Hygiene in Children with Mild Intellectual Disability and Moderate Dental Anxiety: A Randomized Clinical Trial
Background and Objectives: Children with mild intellectual disability (MID) frequently experience difficulties during dental treatment due to increased sensitivity to environmental stimuli and limited cooperation. Sensory-adapted dental environments (SADE) have been proposed as a strategy to improve the dental experience of patients with neurodevelopmental conditions; however, evidence regarding their effectiveness in children with MID remains… →
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The Effect of Using Hypotension Prediction Index to Reduce Intraoperative Hypotension in Elective Cesarean Sections: A Randomized Controlled Trial
Background and Objectives: The Hypotension Prediction Index (HPI) is a predictive algorithm that enables proactive management of intraoperative hypotension (IOH) and has been integrated into finger cuff devices for practical use in obstetric settings. This study aims to evaluate the effectiveness of HPI in reducing IOH during elective cesarean sections (CS). Materials and Methods: This… →