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  • Efficacy and safety of the Chinese herbal medicine Xiao’er Niuhuang antipyretic plaster for treating fever in children with acute upper respiratory tract infection with wind-heat syndrome: a multicenter, randomized, double-blind, controlled clinical trial

    28 июня, 2026

    CONCLUSION: Xiao’er Niuhuang antipyretic plaster is an effective and safe treatment for fever in children with AURI and wind-heat syndrome. →

    Clinical Trials
  • Effects of Short-Term Versus Long-Term Mentalization-Based Therapy on Psychiatric Symptoms in Outpatients With Borderline Personality Disorder: Exploratory Results From a Randomized Clinical Trial

    28 июня, 2026

    We conducted a randomized clinical trial assessing the beneficial and harmful effects of short-term versus long-term mentalization-based therapy (MBT) for outpatients with borderline personality disorder (BPD) and found no evidence of a difference on BPD symptom severity, functional impairment, quality of life, global functioning, and severe self-harm. In this paper, we assessed the effects of… →

    Clinical Trials
  • Effects of Ayres sensory integration therapy versus conservative treatment in autism spectrum disorder

    28 июня, 2026

    The study was conducted to evaluate the effects of Ayres sensory integration therapy versus conservative treatment in autism spectrum disorder. In a prospective randomised controlled trial, we assessed pre- and post-intervention scores of both the intervention group (A) that took ASI and the control group (B) that received conservative treatment-only behaviour therapy, speech therapy, and… →

    Clinical Trials
  • Comparison of capsular stretching and passive joint mobilisation in idiopathic adhesive capsulitis of the shoulder: A randomised controlled trial

    28 июня, 2026

    CONCLUSIONS: Both interventions significantly improved shoulder range of motion and reduced pain and disability. However, greater improvements were observed in shoulder flexion, extension, abduction, and SPADI scores in the control group, while internal rotation improved more in the experimental group, with similar gains in external rotation. →

    Clinical Trials
  • Transcranial direct current stimulation in affecting neuropsychiatric symptoms of post-COVID syndrome: No change in microstates and functional connectivity

    27 июня, 2026

    CONCLUSIONS: We did not find a significant difference in selected EEG parameters between active and sham groups. The possible reasons include choice of tDCS parameters (electrode montage or stimulation duration), and EEG variables selected for evaluation (microstates and functional connectivity). These results are in line with the results of cognitive and clinical assessment. However, the… →

    Clinical Trials
  • Role of individualized intervention(s) on quality of life and adherence to adjuvant endocrine therapy in premenopausal women with early-stage breast cancer: MyCHOICE study

    27 июня, 2026

    CONCLUSION: Individualized, patient-selected supportive interventions may help maintain key aspects of quality of life and support adherence to endocrine therapy in premenopausal women with early-stage breast cancer. These findings support further evaluation in larger, controlled trials. →

    Clinical Trials
  • Efficacy and Safety of Lianhua Qingke Tablets in Children With Mycoplasma pneumoniae Pneumonia: A Randomized, Double-Blind, Multicenter, Placebo-Controlled Clinical Trial

    27 июня, 2026

    CONCLUSION: LHQK is a safe and effective adjunctive TCM therapy for mild MPP in children, offering significant benefits in respiratory symptom alleviation and a favorable safety profile, with a trend toward shorter recovery time, providing a valuable treatment option amid rising antibiotic resistance. →

    Clinical Trials
  • Effects of Modest Carbohydrate-Energy Supplementation on Resistance Training Adaptations in Trained Men: A Crossover Trial

    27 июня, 2026

    Background/Objectives: Higher energy and carbohydrate intakes have been hypothesized to enhance resistance training adaptations, yet empirical evidence remains mixed. The purpose of this study was to investigate whether supplemental carbohydrate-energy intake improves muscle hypertrophy and strength. Methods: Twenty resistance-trained men (26.7 ± 4.9 years old, 9.7 ± 6.1 years training experience) completed a quasi-randomized, double-blinded,… →

    Clinical Trials
  • Evaluation of the Effect of Astragalus membranaceus Saponins Administration on Knee Function and Cartilage Biomarkers in Healthy Subjects with Knee Discomfort

    27 июня, 2026

    CONCLUSIONS: 12 weeks of AMS supplementation was associated with improvements in selected functional, mobility, and outcomes in generally healthy adults with self-reported knee discomfort. AMS was also associated with changes in selected circulating biomarkers related to inflammation and cartilage metabolism. These findings should be interpreted as a preliminary, safe, complementary strategy to support joint health… →

    Clinical Trials
  • Sensitive Skin Improvement Through Bioinformatics-Identified Cosmetic Ingredients That Regulate Transcriptome-Derived Biomarkers

    27 июня, 2026

    Sensitive skin is characterized by hypersensitivity to normal stimuli, and objective diagnostic tools and treatments are still limited. Currently, cosmetics for sensitive skin are developed through the exclusion of known irritants rather than investigation into the underlying mechanisms of sensitivity. In this study, we developed an integrated pipeline combining transcriptome analysis via microneedle-based skin sampling… →

    Clinical Trials
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