• Sintilimab plus concurrent chemoradiotherapy for treatment of locally advanced small cell lung cancer (SINCE-01): a phase II clinical trial

    Patients diagnosed with limited-stage small cell lung cancer (LS-SCLC) face dismal long-term outcomes, as relapse occurs frequently even after standard concurrent chemoradiotherapy. Integrating immune checkpoint blockade into chemoradiotherapy regimens may enhance sustained disease control, yet prospective evidence for this strategy in LS-SCLC remains sparse. In this single-arm phase II study, we investigated sintilimab in combination…

  • Respect begets retention: Why good supervisors matter in garment export factories 

    When workers quit their roles in garment factories, it’s a significant event, potentially disrupting supply chains and productivity. Sazid Ahmad argues that supervisor interpersonal justice—treating workers with politeness and respect or taking their side when they make a mistake—can both improve wellbeing and lower quitting intention.  Do you wish your boss treated you a little nicer, or supported you if you made mistakes? These concerns are particularly…

  • How Nespresso Builds Sustainability Into Its Business Model

    Photo courtesy of Nestlé Jean-Christophe Jaunin became CEO of Nespresso North America, the Nestlé unit that sells coffee brewing machines and capsules, on Jan. 1, 2026, after having served as global chief customer and technology officer. At the NYU Stern Center for Sustainable Business’s annual practice forum in March, MIT Sloan Management Review spoke with…

  • Our Guide to the Summer 2026 Issue

    Create Generative AI Value at Scale Kevin Schmitt, Gregory Vial, and Ivo Blohm Key Insight: Organizations are expanding their GenAI use by implementing coordinated cross-functional structures that draw on domain expertise and user innovation. Top Takeaways: Companies that establish a new kind of internal AI organization that researchers have dubbed the “AI spine” are better…

  • What Wise Leaders Understand About Business Ecosystems

    It’s safe to say that most people who rise to the top of their companies like to win. A healthy competitive streak is energizing and motivates individuals and teams to do their best — to find their edge and sharpen it. But sustained, long-term success and industry leadership often rely on the ability to look…

  • Why AI Isn’t Transforming Finance Yet

    Christian Gralingen The Research The authors engaged in two complementary research streams. One was a multiyear program of action design research conducted with organizations undergoing digital transformation that focused on how leadership work evolves under conditions of technological and market uncertainty. The other, a study of how AI is introduced into finance functions and how…

  • Scaling AI With Adaptive Governance

    Christian Gralingen The Research From 2022 to 2025, the authors conducted in-depth, semistructured interviews with senior leaders and practitioners responsible for AI governance, risk, compliance, data, and product decisions. Core interviews were conducted at Microsoft, Barclays, Kyriba, Nasdaq, Lloyds Bank, Danske Bank, and the Abu Dhabi Department of Finance. The interviews focused on how governance…

  • Three Things to Know About Assessing Customer Reviews

    master1305/Getty Images How should companies effectively use or respond to an unwieldy array of customer opinions? While consumer feedback can be invaluable, three recent research articles suggest that it may also be influenced by gender, niche preferences, or sky-high expectations, complicating whether and how companies should respond. 1. Not all users post critical reviews. A…

  • A Three-Minute Protocol to Reduce AI Manipulation Risk

    izusek/Getty Images Of the potential weaknesses of any security system, the human layer has always posed a key risk. The arrival of AI tools has made human cognition even more of a vulnerability. Companies face three overlapping security threats from AI’s effects on human cognition. First, weaponized persuasion lets attackers manipulate employees’ judgment through personalized,…

  • Does Cultural Training Help Expats Succeed?

    funky-data/Getty Images Every year, multinational corporations invest billions in global mobility programs. The standard playbook includes training in the customs, values, and communication styles of the host country. However, our meta-analysis of research on migrants, including relocated workers, suggests that cultural knowledge plays a minimal role in expats’ successful adjustment. In a study recently published…