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Why Women Professors Are More Likely to Leave Their Jobs
Women professors are more likely than men to leave their jobs. And when they do, people often assume it’s because of difficulties juggling their professional and personal lives. “Much of the past literature on women academics—tenure-line professors in particular—talks about how one of the major barriers to success that may push them out of the… →
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For Loans, It Pays to Compare
Time and again, people settle for mediocre loans. It’s a baffling outcome, given that, with just a bit more searching, they could secure better rates and potentially save themselves thousands or tens of thousands of dollars. In the economist’s eye, the simple explanation for this behavior is that many people aren’t willing to put in… →
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When Bundling Hurts the Bottom Line
Lebron James versus Stephen Curry. Victor Wembanyama versus Luka Doncic. When the biggest names in the National Basketball Association get together to compete in the league’s annual All-Star game, fans from all around the world flock to the chosen city. The popularity of the event opens a brief but tremendous window of opportunity, not just… →
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Tiger Team, Assemble!
When an organization seeks transformational change—whether that’s a new approach to sales, a better product, or a cultural reset—it’s often left to the C-suite to generate new ideas. “The top decides a strategy, and they expect people to go out and execute on it,” says Sanjay Khosla, a senior fellow and adjunct professor of marketing… →
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Effects of Dual-Task Training With and Without Backward Walking on Balance, Functional Mobility, and Participation in Ambulatory Children With Spastic Diplegic Cerebral Palsy: A Randomized Controlled Trial
CONCLUSIONS: In ambulatory children with spastic diplegic CP (GMFCS Levels I-II), adding BW to DTT was associated with a small additional improvement in functional mobility over 4 weeks (approximately 1 s on the TUG) of uncertain clinical importance, whereas superiority for balance or participation was not demonstrated; the trial was not powered for these secondary… →
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Effect of Preoperative Intranasal Dexmedetomidine on Postoperative Myocardial Injury in Patients Undergoing Coronary Artery Bypass Grafting
CONCLUSION: In this single-center trial, two-dose preoperative intranasal dexmedetomidine was associated with lower postoperative hs-cTnT and CK-MB concentrations, better subjective preoperative sleep quality, and a lower observed incidence of postoperative delirium. These findings are preliminary and require confirmation in larger, adequately powered multicenter randomized trials to determine whether the biomarker reductions translate into clinically meaningful… →
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Microbiome-derived TOPOSCORE is associated with response to immune checkpoint inhibitor re-induction after chemotherapy in primary resistant metastatic melanoma
CONCLUSIONS: Baseline TOPOSCORE classification was insufficient to predict treatment outcome in this cohort. Longitudinal TOPOSCORE patterns were heterogeneous, and the small number of complete longitudinal profiles precludes conclusions that chemotherapy induced a favorable microbiome transition. These exploratory findings support further evaluation of microbiome ecosystem dynamics in larger prospective cohorts. →
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Effect of discharge planning rooted in the integrated Care for Older People Concept on the maintenance of intrinsic capacity in older adults
CONCLUSION: The ICOPE-based DP approach slows IC decline and enhances multiple functional domains, offering a valuable reference for transitional care for older adults. →
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Eltrombopag during induction chemotherapy in older patients with newly diagnosed acute myeloid leukemia is safe and reduces platelet transfusion requirements: The EPAG-2015 French Innovative Leukemia Organization phase 2 randomized trial
CONCLUSIONS: This study failed to demonstrate a survival advantage after eltrombopag addition, at variance with previous reports, but shows that initiating eltrombopag after chemotherapy washout is feasible and safe, and resulted in a decreased need for platelet transfusions. →
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A multilevel intervention to improve adherence to prostate cancer active surveillance versus usual care: results from a pilot randomized controlled trial
CONCLUSIONS: This study demonstrated a multilevel intervention (MAP) is feasible to deploy and acceptable. Importantly, MAP shows promise in building patient confidence about team-based active surveillance care delivery and increased primary care involvement through targeted education around the role or primary care. →
