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Effects of a fall prevention program on falls among rural older adults with cardiovascular disease in China: a secondary analysis of the FAMILY cluster randomised trial
CONCLUSIONS: A village doctor-led fall-prevention program integrated into rural primary care reduced falls and fall-related injuries and improved functional outcomes among older adults with CVD. These findings support integrating scalable nonpharmacological fall-prevention strategies into routine cardiovascular management in rural primary care. →
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Exploring Immersive Virtual Reality as an Approach to Improve School Participation-Related Constructs in Children With ADHD
CONCLUSIONS: Findings suggest that the IVR program was associated with improvements in teacher-rated environmental and child determinants of school participation (SPQ domains) in children with ADHD. →
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How to End Things Well
Aad Goudappel/theispot.com Most leadership advice is written for beginnings — how to launch initiatives, build momentum, scale ideas, and manage new projects. Far less attention is given to the work of ending something well. Yet endings are everywhere in organizational life. A team is disbanded. A project is closed. A product is retired. A partnership… →
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AI Could Help Researchers Get Funding—But at What Cost?
From helping business students with their homework to assessing people’s empathy, large language models (LLMs) like ChatGPT and Claude are having a meaningful impact on more and more aspects of our lives. While many of us are just starting to get comfortable with AI’s role in our work, scientists have actually been leveraging AI to… →
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Comparison of ACEs reporting between clinic and telephone-based screening
CONCLUSIONS: Telephone-based screening may be effective for sensitive questions. Specific family factors may affect which screening approaches are preferable. →
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Transforming Air Cargo Operations: Optimizing with Vision & Robotics – OpenCV Live Ep. 220
Air cargo still runs on estimates — dimensions eyeballed at acceptance, and containers packed by “feel.” Suraj Nair, founder of Singapore-based Speedcargo, joins OpenCV Live to show how 3D computer vision, optimization algorithms, and gantry robotics replace that guesswork with measured cargo data. He’ll cover what it takes to get perception working reliably in a… →
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Automated intermittent olfactory stimulation to reduce apnea in preterm infants: results of the PREMODEUR randomized clinical trial
CONCLUSION: Automated intermittent olfactory stimulation did not significantly reduce apnea incidence in the primary analysis. Given the limited sample size, a modest treatment effect cannot be excluded; however, the exploratory post hoc analysis does not provide confirmatory evidence of efficacy. These findings may help inform the design of larger, adequately powered trials with earlier recruitment… →
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Analysis of surgical efficacy in patients with chronic suppurative otitis media complicated by fungal infection
Objective:To analyze the clinical efficacy of tympanoplasty in patients with chronic suppurative otitis media（CSOM） complicated by fungal infection through a prospective randomized controlled study, and to explore the optimal surgical timing for chronic otitis media patients accompanied by fungal infection. Methods:A total of 92 patients diagnosed with chronic otitis media who were admitted to Yinchuan… →
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Applying a Pharmacometrics-Enabled Machine Learning Analysis to Predict 2-Month Culture Conversion Using Phase 2a Data in a Tuberculosis Clinical Trial
Phase 2a trials in tuberculosis patients traditionally assess early bactericidal activity over two weeks, often using the time-to-positivity biomarker, followed by a phase 2b study typically lasting 8-week with time-to-event of culture conversion as the endpoint. This study investigated different machine learning models to predict the time-to-event of 2-month culture conversion in the REMoxTB trial… →
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The Cost and Intermediate Cost-Effectiveness of a Randomized Control Trial Delivering U=U Messaging to Increase HIV Testing Among South African Men
CONCLUSION: Delivering tailored U=U messaging can increase HIV testing and ART uptake among men while saving costs over standard untargeted HIV testing messaging and other HIV self-test distribution models. →
