Acute elevation in circulating lipids induces reversible insulin resistance and alters triglyceride-rich lipoprotein flux. Whether insulin-regulated remodelling of high-density lipoprotein (HDL)-associated apolipoproteins is altered during defined lipid stress in women with polyendocrine metabolic ovarian syndrome (PMOS) remains unclear. In this exploratory, randomized, cross-over study, 10 healthy women and 12 women with PMOS underwent 5-h saline… →

CONCLUSIONS: MUAC z-score tapes were repeatedly applied for nutrition risk screening in the ALIMUS study, supporting the penetration and adoption of their use by CHVs working in remote and low-resource community settings. →

INTRODUCTION: Recognising and acting on the connection to Country as a determinant of Indigenous peoples’ well-being is necessary to improve health inequities. Indigenous Australians experience a greater burden of chronic liver disease and poorer outcomes due to ongoing impacts of colonisation across determinants of health. This is exacerbated by a gradient in health outcomes based… →

BACKGROUND: Vanishing white matter is a neurodegenerative disease with onset mostly in children aged 1-6 years that causes early death and has no effective therapy. The disease is caused by a genetic defect affecting eukaryotic initiation factor 2B, a key regulator of the integrated stress response. The α2-adrenergic antihypertensive drug guanabenz inhibits this stress response… →

CONCLUSIONS: An eight-week, thrice-weekly physiotherapy-based balance, coordination, and strengthening program improves motor proficiency, posture, gait, and muscle strength in children with low vision, supporting its use in pediatric rehabilitation. →

Dizziness and vertigo are common and debilitating neurological symptoms among patients visiting the emergency department (ED). Possibly because the symptoms are not captured by standard stroke severity tools such as the NIHSS (National Institutes of Health Stroke Scale), their network-level neuroanatomical correlates-particularly potential supratentorial contributions-remain incompletely characterized. Therefore, we aim to investigate the neuroanatomical substrates… →

CONCLUSIONS: A village doctor-led fall-prevention program integrated into rural primary care reduced falls and fall-related injuries and improved functional outcomes among older adults with CVD. These findings support integrating scalable nonpharmacological fall-prevention strategies into routine cardiovascular management in rural primary care. →

CONCLUSIONS: Findings suggest that the IVR program was associated with improvements in teacher-rated environmental and child determinants of school participation (SPQ domains) in children with ADHD. →