This study compared Intraneural Facilitation (INF^(®)) therapy and standard physical therapy (PT) in preventing chemotherapy-induced peripheral neuropathy (CIPN) in women with newly diagnosed breast and gynecologic cancer. Thirty-eight women undergoing platinum and/or taxane-based chemotherapy, without prior peripheral neuropathy, were randomized into INF^(®) therapy (n = 20) and PT (n = 18). Treatments lasted 45 minutes,… →

CONCLUSIONS: LNG-IUS is highly cost-effective compared with HNR for the treatment of niche-related postmenstrual spotting at 6 months. These findings support LNG-IUS as first-line therapy for niche-related spotting in women with a residual myometrium ≥2.2 mm. →

Post-COVID syndrome is widely recognised in children and young people (CYP), where one or more persistent physical symptoms are present 12 weeks after the initial infection that cannot be explained by an alternative cause. We aimed to assess whether an intervention based on narrative therapy and breathing pattern retraining, co-designed with CYP with PCS (12-18… →

CONCLUSION: Primary care providers with results from a definitive saliva-based test for MNA and DDI were significantly more likely to identify those common challenges and make appropriate updates to the patient’s treatment plan. This has important implications for improving quality and value, especially for the millions of patients with chronic conditions on multiple medications. →

To describe and standardize a position-guided nasopharyngeal irrigation protocol for post-radiotherapy nasopharyngeal ulceration (RINU) in patients with nasopharyngeal carcinoma (NPC), a prospective comparative clinical setting was used among 184 patients diagnosed with RINU between January and March 2025. Participants were randomly assigned to receive either routine manual irrigation (n = 92) or irrigation using an… →

This study analyzed the impact of crisis management on premature rupture of membranes (PROM). Between March 2023 and April 2025, 146 pregnant women diagnosed with PROM were recruited from Heilongjiang Provincial Hospital. The cohort was randomized using computer-generated random numbers with concealed allocation envelopes into an intervention group (n=73) employing crisis management strategies and a… →

BackgroundThe routine use of postoperative drainage after total knee arthroplasty (TKA) remains controversial, particularly in the era of modern blood-saving strategies. While drains have traditionally been used to reduce hematoma formation, their effect on early postoperative pain has not been clearly established. This study aimed to evaluate whether postoperative drainage influences early pain outcomes following… →

CONCLUSION: NHF reduced RR by shortening both inspiratory and expiratory times without altering the duty cycle. The lower MV during NHF with AI, accompanied by higher SpO(2), may indicate improved gas exchange efficiency. The use of AI could enhance the respiratory support effects of NHF in patients with advanced COPD. →