CONCLUSIONS: A 12-hour eating window, particularly with the last meal completed before 8 PM, may be associated with lower BP over 12 months in children and adolescents with elevated BP; interpretation should consider the cluster design and attrition. →

BACKGROUND Chronic lateral epicondylitis (LE) causes persistent pain and functional impairment. Blood flow restriction training (BFRT) can improve strength and pain under low-load conditions, but evidence in chronic LE remains limited. This study investigated the effects of combining BFRT with conventional therapy on pain, muscle strength, function, and psychosocial outcomes. MATERIAL AND METHODS A single-blind… →

CONCLUSIONS: Acupuncture at force-sensitive acupoints has a definite curative effect on IBS-D. This therapy is high in safety and satisfactory in long-term effect. In the aspects of the alleviation of the severity of symptoms and the improvement of the quality of life in the patients with IBS-D, acupuncture at force-sensitive acupoints with high sensitivity is… →

This phase 2 study evaluated the efficacy and safety of combining acalabrutinib and lenalidomide with either rituximab (ALR) or obinutuzumab (ALO), with longitudinal minimal residual disease (MRD) monitoring in frontline MCL treatment. The primary objective was molecular complete response (CR) after 12 cycles of induction, defined by Lugano criteria, and undetectable MRD of <10-6 (uMRD6)… →

CONCLUSION: For patients with difficulty establishing venous access routes, ultra-low contrast agent flow rates in PCD-CT maintain objective image quality comparable to that of standard protocols, with acceptable diagnostic performance despite slight reductions. →

CONCLUSIONS: Conducting a double-blind, placebo-controlled randomized trial of single-dose versus multidose oral amoxicillin challenge was feasible. A fully powered efficacy trial is needed to assess between-group differences in immune-mediated adverse events. (Funded by Austin Health and others; trial registration: ANZCTR — ACTRN12623001242617, registered on November 30, 2023.). →

CONCLUSION: Our results provide clear evidence that IAFG is a safe and effective surgical technique that does not increase the risk of local or distant recurrence in breast cancer patients and yields higher satisfaction with postoperative breast appearance and psychosocial outcomes. →

CONCLUSION: Higher breathing frequencies significantly reduce total Rrs . When performing respiratory oscillometry, breathing frequency should be controlled at approximately 15 bpm to reduce risk of misclassification. →

CONCLUSIONS: On average, COS-P was associated with higher costs and did not demonstrate improvements in health-related quality of life compared with TAU alone. Given the uncertainty surrounding the estimates, further research is warranted to explore potential longer term economic and clinical impacts of COS-P in perinatal mental health settings. →