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Single-Entry-Point Thread Implantation Technique Using the Gerbera Pattern for Facial Skin Rejuvenation: A Prospective Intraindividual Controlled Clinical Study
CONCLUSION: The single-entry-point thread implantation technique using the Gerbera pattern significantly reduced pain at needle penetration compared with the conventional multiple-entry-point technique, demonstrating good tolerability in clinical practice. →
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Sex- and Age-Stratified Outcomes of Colonoscopy Versus Faecal Immunochemical Testing: Post-Analysis of the COLONPREV Study
CONCLUSION: Participation and reductions in CRC-related mortality and incidence were consistent across sex and age groups for both FIT- and colonoscopy-based screening strategies. The higher baseline risk observed in men could not be fully mitigated by screening. →
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Cost and cost-effectiveness of ivermectin mass drug administration for malaria control in Kwale county, Kenya: a modelling analysis of a cluster-randomised trial
BACKGROUND: Malaria remains a major health burden in sub-Saharan Africa, where traditional vector control methods are hindered by insecticide resistance and evolving mosquito behaviour causing residual transmission. In the BOHEMIA cluster-randomised trial in Kenya, ivermectin mass drug administration (iMDA), delivered once a month for 3 months with approximately 64% population coverage, was shown to reduce… →
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A Randomized Clinical Trial: The Comparative Therapeutic Efficacy of Tap Water-UVA, Saltwater-UVA, and Conventional Bath PUVA in Palmoplantar Pustulosis
CONCLUSIONS: Immersion in water or saltwater prior to UVA without psoralens may provide a therapeutic effect. →
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Cost-effectiveness of transdiagnostic group cognitive behavioral therapy for emotional disorders in primary care: An analysis of the PsicAP clinical trial
CONCLUSIONS: The integration of TD-GCBT into TAU represents a cost-effective therapeutic approach. The incremental cost-effectiveness ratio of 4,759€ per quality-adjusted life years is well below the willingness-to-pay threshold accepted in Spain, which ranges from 20,000€ to 25,000€. At this threshold, the probability that the intervention is cost-effective is high, ranging from 86% to 89%. Therefore,… →
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Ask Sanyin: What Makes a ‘Listening Tour’ Meaningful?
Carolyn Geason-Beissel/MIT SMR | Getty Images I’ve just stepped into a new leadership role and was advised to embark on a “listening tour.” I’ve gone out and spent time with different units and functions, but I’m not sure it’s helping. Conversations feel surface-level, and I’m not learning what I need to lead effectively. What am… →
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Impact of cannabidiol on myocardial recovery in patients with acute myocarditis: primary results of the ARCHER study
CONCLUSION: In mild-to-moderate acute myocarditis, treatment with pharmaceutically manufactured cannabidiol was not associated with a statistically significant change in myocardial ECV or GLS, although a trend towards reduction in ECV was observed. In addition, improvement in other potential markers of myocardial recovery, including a significant reduction in LV mass, was seen in the active treatment… →
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Ensifentrine Added on to Dual Bronchodilator or Triple Therapy Demonstrates Clinically Meaningful Improvement in CAT Score in Symptomatic Patients with Chronic Obstructive Pulmonary Disease
CONCLUSION: Ensifentrine provided clinically meaningful improvement in health status measured by CAT score in two-thirds of symptomatic patients with COPD taking dual bronchodilator or triple therapy in a real-world setting. →
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The relationship of oral malodor to gingivitis: cross-sectional epidemiology and longitudinal randomized clinical trial evidence
This research assessed the relationship between oral malodor, measured by halimetry and organoleptic grading, and gingivitis as measured by number of gingival bleeding sites (GBS). Two complementary clinical studies were examined. The first was a cross-sectional trial evaluating the association between volatile sulfur compounds measured by halimetry and organoleptic scores (0-5 scale). The second study… →
