CONCLUSION: Inhaled NO therapy in complex therapy of PE demonstrated safety and efficacy in relation to clinical, functional and laboratory parameters. →

CONCLUSION: Cipepofol exhibited no clinically relevant effects on the QTc interval or other ECG parameters, and was safe and well tolerated in healthy subjects. →

CONCLUSION: The one-step 75 g OGTT increases diagnostic labeling without improving short-term clinical outcomes. Post-load OGTT values-particularly 2-hour glucose levels-provide the most clinically meaningful prognostic information and may support a risk-stratified approach to GDM management rather than expansion of diagnostic thresholds alone. →

BACKGROUND: This study aimed to test whether the Meaning-Making intervention (MMi) increases the sense of meaning in life in people newly diagnosed with any type of advanced cancer. →

CONCLUSION: pTDM is very likely a cost-effective treatment strategy for patients with immune-mediated inflammatory diseases on infliximab maintenance therapy. →

CONCLUSIONS: The home-based DEP following Achilles tendon repair provided comparable clinical outcomes to traditional physiotherapy while significantly improving cost-effectiveness. These findings support the broader adoption of tele-supervised digital rehabilitation as a safe and effective alternative. →

CONCLUSIONS: The innovative patient education model integrating AI voice cloning and ChatGPT is distinct from previous studies primarily relying on standard text-to-speech or professionally recorded content. Using patients’ own cloned voices for health education delivery leveraged the self-reference effect to enhance learning outcomes. Compared with research using clinician-narrated content, this study highlights that self-voice education… →

CONCLUSION: The VISCIPH B pilot trial confirmed the feasibility, safety, and acceptance of supervised exercise for upper-extremity PNP in cancer patients. Significant improvements in patient-reported and functional outcomes indicate that combined sensorimotor and vibration exercise can meaningfully reduce PNP symptoms and should be evaluated in larger trials. →

CONCLUSIONS AND RELEVANCE: In this randomized clinical trial of patients undergoing diagnostic cerebral angiography, TRA was not shown to be noninferior to TFA with regard to the success rate of diagnostic cerebral angiography. Additional research, including superiority trials, is needed to clearly define the comparative benefits of TRA and TFA. →