CONCLUSIONS: The program, combining rehabilitation for the person with dementia with caregiver support, seems feasible regarding caregivers’ participation in the intervention and study evaluation, and thus further evaluation in an adequately powered randomized controlled trial seems relevant. A future definitive trial should evaluate continuous support over a longer period adapted to the caregiver and refine… →

CONCLUSION: PMRT was associated with greater improvements in PTSD symptoms, psychological well-being, sleep quality, fatigue, and quality of life compared to an education-only control group. Telerehabilitation may offer a practical advantage when face-to-face care is limited, although this remains speculative. →

CONCLUSIONS: Use of AAC did not improve detection of neoplasia in patients with Barrett’s oesophagus undergoing endoscopic surveillance in routine clinical practice. →

CONCLUSIONS AND RELEVANCE: This study’s findings suggest that centralized mailed FIT outreach could increase CRC screening in FQHCs serving populations with persistent disparities, although maintaining intervention fidelity and providing ongoing implementation support over time are needed for consistent impact. →

This Phase I, randomized, placebo-controlled, double-blind study (NCT06625489) evaluated pharmacokinetics (PK), safety, and tolerability of the transglutaminase 2 inhibitor suvigletistat in Chinese, Japanese, and White/European participants. Eligible participants: aged 18-50 years, healthy, and of Chinese, Japanese, or White/European ancestry. Thirty-six participants (12 per ancestry group) were randomized 3:1 to receive suvigletistat (160 mg single oral… →

BackgroundLittle is known about the role of oxytocin in the processing of positive emotional infant cues in mothers with PPD.ObjectivesWe therefore examined whether intranasal oxytocin influences postpartum mothers’ processing of positive infant emotional cues, both visual (facial expressions) and auditory (laughter), and intended caregiving responses.DesignThis double-blind randomized controlled crossover study included 45 mothers, with 3-… →

CONCLUSION: This study may help to better understand the effects of IMT performed at different loads on peripheral muscle oxygenation behavior, as well on the autonomic response in patients with COPD. These findings may improve the understanding of the physiological impacts of this therapy and support its application in pulmonary rehabilitation programs. →