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  • Belimumab outperforms placebo for attainment of modified DORIS remission and LLDAS without the glucocorticoid component: a post hoc analysis of five phase III SLE trials

    4 июля, 2026

    CONCLUSION: Belimumab was associated with higher attainment of DORIS remission and LLDAS excluding the GC component versus placebo; attainment rates were approximately twofold higher than those previously reported using the full definitions. →

    Clinical Trials
  • Treat-to-target strategies are feasible in elderly-onset rheumatoid arthritis given its reassuring risk-benefit profile

    4 июля, 2026

    CONCLUSION: A T2T approach is feasible and effective in EORA, given its reassuring risk-benefit profile, while recognising the need for individualised management. →

    Clinical Trials
  • Interesterified fats rich in palmitic and stearic acids have comparable effects on selected inflammatory related biomarkers

    3 июля, 2026

    CONCLUSIONS: The finding suggests that the long-term effects of these three fats on these selected inflammatory related biomarkers are similar. Trial registration https://clinicaltrials.gov/ , NCT02192047, 2014-07-15. →

    Clinical Trials
  • Effect of community-based intensive smoking cessation intervention on smoking behavior and blood pressure control in hypertensive patients

    3 июля, 2026

    CONCLUSION: The intensive smoking cessation intervention significantly increased smoking abstinence rates, reduced cigarette consumption, and improved blood pressure control among hypertensive patients in community settings. →

    Clinical Trials
  • Digital Simulation-Based Ultrasound Training for Physiotherapy Students: Prospective Randomized Controlled Trial

    3 июля, 2026

    CONCLUSIONS: Simulation-based online ultrasound training provides comparable theoretical and practical outcomes to traditional on-site instruction, supporting its use as a scalable and accessible educational alternative. →

    Clinical Trials
  • Toward evidence-based prescription of prosthetic ankle-foot devices: A multisite randomized crossover trial identifying performance-based, patient-reported, and biomechanical parameters sensitive to device type

    3 июля, 2026

    Prescription of prosthetic ankle-foot devices is constrained by imprecise clinical guidelines and inconsistent scientific evidence, hindering optimal device selection for individuals with lower limb loss. This multisite, prospective, randomized crossover study aimed to identify patient-reported, performance-based, and biomechanical parameters sensitive to ankle-foot device type, providing a foundation for more objective and individualized prescription practices. Ninety-one… →

    Clinical Trials
  • GTM: Why a $1.2B exit felt like his biggest failure, and the customer-obsession thesis behind Agency

    3 июля, 2026

    Listen on YouTube // Apple // Spotify You can also listen to the full episode on X. Brought to you by: Most teams are either paying for tools they’ve outgrown, or making decisions with no real data behind them. Ahrefs is fixing that — for free. Ahrefs Free gives you permanent access to six of… →

    AI Sales
  • Testing behavioral economics principles in mailed FIT outreach: a randomized trial

    2 июля, 2026

    CONCLUSION: The FIT test screening rate in the enhanced communication group was not statistically different from the original communication group. Using evidence-based behavioral economics principles in mailed FIT communications did not markedly improve the rate of CRC screening, but mailed FIT remains a key, cost-effective tool for reaching unscreened individuals. →

    Clinical Trials
  • Traditional Chinese medicine syndrome patterns and associated factors in adults with type 2 diabetes and metabolic syndrome: a data-driven analysis

    2 июля, 2026

    CONCLUSION: This study demonstrates that complementary data-driven methods, specifically PCA and LCA, can effectively map the heterogeneous landscape of TCM syndromes in patients with comorbid T2DM and MetS. The analysis validates core constructs, including Phlegm and Blood Stasis, and links deficiency syndromes to severe fatigue and poor sleep. Future TCM syndrome research may benefit from… →

    Clinical Trials
  • Decoding patient preferences: key drivers in selecting thyroid cancer surgery- a discrete choice experiment

    2 июля, 2026

    CONCLUSION: Recurrence risk is the primary driver of surgical preference in PTC patients, followed by cosmetic outcomes. Additionally, postoperative cosmetic concerns varied across different demographic groups. These findings highlight the need for surgeons to consider patient-specific values during preoperative consultations to enhance shared decision-making. →

    Clinical Trials
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