CONCLUSIONS AND RELEVANCE: In this randomized clinical trial of structured ENC triggered by a machine-learning AKI risk score, there was no difference in ΔSCr. AKI consultation recommendations were not followed the majority of time; whether increasing adherence to recommendations could improve outcomes deserves further study. →

CONCLUSION: IMT is feasible and safe in medically fragile MCS patients and may induce right-hemisphere cortical activation. These pilot findings are hypothesis-generating and require confirmation in larger, adequately powered trials. →

CONCLUSIONS: Early implementation of CRRT in patients with ECMO showed no evidence of a difference in 30-day mortality compared with conventional initiation. However, the trial was substantially underpowered and clinically important benefits or harms cannot be excluded. →

CONCLUSION: Both GGR and SNAPPS teaching methods effectively enhance CR skills among undergraduate medical students. However, GGR demonstrated greater effectiveness in CR domains requiring deeper analytical thinking and collaborative reflection, especially when managing complex cases. Incorporating GGR within undergraduate clinical clerkships may strengthen diagnostic reasoning, particularly in settings with limited faculty-student teaching opportunities. →

BACKGROUND: Excessive daytime sleepiness (EDS) is a major yet under-recognized contributor to road traffic accidents. Traditional diagnostic tools, such as the Maintenance of Wakefulness Test (MWT), assess wakefulness under passive conditions but may not accurately reflect real-world driving risks. To address this gap, we have piloted a Driving Simulation-based MWT (DS-MWT), designed to evaluate sleepiness… →

Relationship distress is a prevalent issue with significant economic and societal consequences, including increased mental and physical health problems, decreased workplace productivity, and increased absences. Although couple therapy has been shown to improve relationship and individual well-being, its high costs limit accessibility. Digital relationship interventions provide a cost-effective alternative. However, limited research has assessed the… →