-
Effects of PosturePals on Pressure Pain Threshold, Muscle Activity, Craniovertebral Angle, and Quality of Life Among Adults with Cervicothoracic Pain Syndrome: Study Protocol for a Randomized Controlled Trial
BACKGROUND: Cervicothoracic pain syndrome (CTPS) is a widespread condition that adversely affects the quality of life (QOL) and is frequently associated with poor posture and muscular imbalance. Despite its prevalence, effective non-invasive interventions remain unexplored. This protocol of a randomized controlled trial (RCT) aims to investigate the effects of PosturePals on pressure pain threshold (PPT),… →
-
Baseline gut microbiota and short-term response to acupressure combined with thermal stimulation in maintenance hemodialysis patients with functional constipation: an exploratory responder analysis
CONCLUSION: Baseline microbial diversity and community structure were similar between responders and non-responders. Veillonella and Lactobacillus showed adjusted associations with response, but neither was robust in sensitivity analysis. These findings should therefore be regarded as exploratory rather than predictive. Larger longitudinal studies are needed to validate these findings and determine their clinical relevance. →
-
Pars plana vitrectomy with silicone oil versus pars plana vitrectomy alone for postoperative endophthalmitis: A randomized controlled trial
CONCLUSION: PPV with SO tamponade significantly reduces recurrent infection and intraocular inflammation in severe postoperative endophthalmitis, leading to trends toward improved visual outcomes. These benefits appear mediated by both anti-infective and anti-inflammatory mechanisms, supporting the use of SO in complex cases. →
-
Efficacy and safety of Lianhua Qingwen versus oseltamivir in children with influenza: a multicenter, randomized, double-blind, positive parallel-controlled study
CONCLUSIONS: LHQW was non-inferior to oseltamivir in clinical recovery time and resulted in faster defervescence and greater improvement in cough and sore throat, with comparable safety. →
-
Photobiomodulation Reduces Physiological Stress and Pain During Dental Diagnostic Procedures: The UM-DANE 1 Pediatric Clinical Trial
Purpose: To evaluate effectiveness of photobiomodulation therapy (PBMT) in reducing physiological stress (as measured by heart rate [HR] change), self-reported pain, and anxiety during cold pulp testing and routine gingival probing in healthy school-aged children. Methods: This prospective, randomized, split-mouth clinical trial enrolled 30 children aged 7 to 12 years at the University of Maryland… →
-
Tracing-based drawing method enhances anatomy learning outcomes and proportional awareness: a randomized cross-over study
CONCLUSION: TBDM was associated with higher drawing performance and more positive learner ratings than TMBM. A positive method contrast was observed at both the immediate and one-week delayed assessments, although the difference was smaller at the delayed assessment. TBDM may provide a low-cost, structured complement to existing anatomy-learning methods. Its longer-term and transferable educational effects… →
-
Low cost app-based intervention DIALOG+ for anxiety and depression in outpatient psychiatric settings: a pragmatic multisite cluster randomized controlled trial
BACKGROUND: Clinically diagnosed anxiety and depressive disorders are widely recognized as the most common mental health issues in India, affecting approximately 15% of the population. With notable gender disparities, Tamil Nadu has some of the highest depression rates in the nation. Despite the growing burden, countries such as India that fall within the low and… →
-
Effects of intranasal insulin on postoperative delirium in older patients with and without type 2 diabetes mellitus: a secondary analysis of a randomized clinical trial
CONCLUSION: Intranasal insulin was associated with reduced POD incidence in older patients with T2DM and exhibited a potential protective effect on postoperative cognition. →
-
What Interruptions Say About Your Organizational Culture
Mark Airs/Ikon Images Leaders tend to talk about culture in abstract terms: values, norms, trust, belonging, and the like. But employees watch for the moments that show how culture actually manifests. During meetings, who gets interrupted? Employees notice whose sentences are cut short, redirected, or quietly overtaken — and whose ideas are allowed full expression.… →