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Effectiveness of a Sodium Intake Monitoring Smartphone Application (NamakBan) on Clinical Outcomes of Patients Diagnosed With Hypertension: A Randomized Clinical Trial
CONCLUSIONS: In this RCT, the NamakBan application, used alongside usual care, was associated with modest but statistically significant improvements in systolic blood pressure, diastolic blood pressure and self-reported sodium intake over 2 months. However, the objective urinary sodium-to-potassium ratio did not differ between groups. The findings should therefore be interpreted with caution: dietary sodium was… →
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Denecimig (Mim8) prophylaxis in children with hemophilia A with or without factor VIII inhibitors
CONCLUSION: Over 52 weeks, denecimig prophylaxis was well tolerated with no safety concerns and provided robust bleed protection, reduced treatment burden, and improved overall health-related quality of life in children with HA. →
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OpenCV to NVIDIA Isaac Sim: Building the Physical AI Pipeline – OpenCV Live! 228
Live Stream Date/Time: Thursday, October 8th, 2026 @ 9am Pacific. NVIDIA Isaac Sim™ is an open source reference framework for robotics simulation, testing, and synthetic data generation in physically based virtual environments. It’s a powerful system which can ingest data from multiple sources—such as computer-aided design (CAD), Unified Robot Description Format (URDF), or real-world captures.… →
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NIHSS and Large Artery Atherosclerosis Affect Efficacy of Dual Antiplatelet Therapy Versus Alteplase for Minor Stroke
CONCLUSIONS: Neurological deficit and LAA may affect efficacy of DAPT versus alteplase in acute minor nondisabling stroke. In patients with NIHSS scores of 0 to 3 due to LAA, DAPT may be associated with numerically higher odds of 90-day functional outcomes compared to alteplase. Given the exploratory nature of this subgroup analysis and no formal… →
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Subacute effects of ketamine on neural correlates of reward processing
Ketamine induces a sequence of temporally distinct effects on brain function, yet its impact on reward processing beyond the acute post-administration phase remains unclear. In this single-blind, placebo-controlled, crossover study, 28 healthy participants received 0.5 mg/kg racemic ketamine or placebo via a 40 min intravenous infusion. Functional magnetic resonance imaging was acquired approximately 5 h… →
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Rehearsal Intelligence: Using Digital Twins for Crisis Readiness
Carolyn Geason-Beissel/MIT SMR | Getty Images In July 2024, the cybersecurity software company CrowdStrike pushed a routine but buggy software update to its platform. In the ensuing 78 minutes, before a patch was deployed, IT systems worldwide crashed. Microsoft estimated that 8.5 million Windows devices were affected. As blue screens of death cascaded across the… →
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Effects of rosehip (Rosa canina) supplementation on orthostatic intolerance symptoms in patients with type 2 diabetes: a randomized double-blind placebo-controlled clinical trial
CONCLUSION: Rosehip extract significantly reduced orthostatic symptom burden and the prevalence of OH in patients with T2DM. Benefits were primarily reflected in symptomatic scores and systolic blood pressure. While promising and well-tolerated, these preliminary results require confirmation in larger, multicenter trials incorporating long-term objective hemodynamic monitoring. →
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Acute effects of volume-matched isometric exercise intensity on vascular function and autonomic regulation in men with elevated blood pressure
Isometric exercise (IE) has been introduced as an effective non-pharmacological strategy for blood pressure (BP) management; however, the influence of exercise intensity remains unclear during lower-limb IE. This study investigated the acute effects of volume-matched high-intensity (HIIE) and low-intensity IE (LIIE) on cardiovascular function in men with elevated BP. Seventeen men with prehypertension or stage… →
