CONCLUSION: rVWF, without or with rFVIII, was efficacious for treating nonsurgical BEs in pediatric patients with severe VWD, with efficacy maintained for up to 4 years and no new safety findings. →

To evaluate the efficacy and safety of an LED red and infrared light therapy for the treatment of chronic nonspecific low back pain. From September to December 2022, 176 patients diagnosed with chronic non-specific low back pain were enrolled and randomly assigned to two groups: the experimental group (n = 89) and the control group… →

CONCLUSION: Different Cryotherapy techniques effectively reduce (POP) and modulate SP expression. Irrigation with cold hypochlorite throughout chemo mechanical process was most effective for pain reduction while final flush with cold saline achieved the greatest decrease in SP. →

CONCLUSION: Eight weeks of organic selenium supplementation significantly improved glycemic indices and insulin sensitivity in patients with T2DM and DPN, without notable adverse effects. These findings suggest that selenium supplementation may serve as a potentially useful adjunctive intervention for improving short-term metabolic control in patients with T2DM and DPN. The approximately 1.2% reduction in HbA1c… →

CONCLUSIONS: OffA can be translated into exercise prescription to reduce pain and improve feelings during isometric exercise in young healthy adults. [Marquette University Institutional Review Board (#4434)]. →

CONCLUSION: This pilot study establishes the feasibility and tolerability of RART in patients with adhesive capsulitis and provides preliminary, exploratory evidence of beneficial effects on pain and range of motion. Given the underpowered final sample size (post hoc power: 68%-70%), these findings should be interpreted with caution and require confirmation in adequately powered future trials. →

CONCLUSIONS: This study will provide relevant evidence on the effect of remote monitoring in individuals receiving LTOT on HRQoL, dyspnea, health status, anxiety and depression, and engagement with data entry through a mobile app. →

CONCLUSIONS: This protocol is designed to provide robust comparative data on manual therapy approaches for SIJ dysfunction. Findings may guide physiotherapy practice by informing evidence-based recommendations for optimal management strategies. →

CONCLUSIONS: SMS was associated with significant reductions in hospital care and total health care utilization costs during the 6-month postdischarge period compared with TAU. These findings support the integration of cost-effective and scalable digital interventions into routine psychiatric discharge pathways to help improve system efficiency in publicly funded health systems. →

CONCLUSIONS: In outpatient neurology practices, pMRI images demonstrated high clinical concordance with sMRI for identifying the presence or absence of structural brain abnormalities and were strongly preferred by patients. These findings support the use of pMRI as a practical point-of-care imaging tool for neurology patients, enabling timely access to structural neuroimaging during the clinical encounter. →