CONCLUSION: The EMDR-IGTP-OTS is a promising intervention for reducing trauma related parental stress symptoms in parents of children with NDDs. Its high feasibility makes it a suitable option for integration into clinical practice to support families facing trauma-related parenting challenges. →

CONCLUSION: Edaravone improved the short-term level of consciousness in severe HIE adult patients, but there was no significant effect on outcome and level of independence in performing activities of daily living. Further investigation into Edaravone’s effectiveness is warranted, particularly in patients with milder forms of HIE, as well as longer follow-up periods. →

BACKGROUND: In sub-Saharan Africa, the burden of diabetes and hypertension is high, alongside a high prevalence of HIV. Whether these conditions can be managed in an integrated way in the community is unknown. We aim to compare integrated community-based care with integrated facility-based care for people with HIV, diabetes, and hypertension in Tanzania and Uganda. →

BACKGROUND AND PURPOSE: Chronic cervical pain is a common disorder and is difficult to manage. Therefore, this study was conducted to investigate the effects of nociceptor hypostimulation versus hyperstimulation on electromyographic (EMG) activity of cervical muscles, myofascial trigger point (MTP) sensitivity, pain intensity, and disability in patients with chronic cervical pain. →

BACKGROUND AND PURPOSE: Children diagnosed with diplegic cerebral palsy frequently experience gait difficulties that can significantly affect their independence and quality of life. The development of advanced technologies presents opportunities to enhance their walking abilities and overall functional performance. The purpose of this study was to determine how children with spastic diplegia performed when walking… →

CONCLUSIONS: Vibegron add-on therapy to an α(1)-blocker may be effective and safe for treating BPH with persistent OAB symptoms. →

Background: Emerging evidence links the gut microbiome to chronic pain processing. Inulin, a prebiotic fibre, modulates the gut microbiome, while physiotherapy-supported exercise (PSE) improves pain and function. We evaluated the effects of inulin supplementation with and without PSE on knee osteoarthritis (OA) pain. Methods: In a 2 × 2 factorial RCT, 117 community-dwelling adults with… →

CONCLUSIONS: Enhanced digital training positively impacted meaningful clinical outcomes and could be replicated for expansion to other evidence-based interventions. →

CONCLUSIONS: EXCAP may reduce CRCI and mental fatigue, particularly in patients receiving 2-week cycles of chemotherapy. A healthy inflammatory response, characterized by increases in both proinflammatory and anti-inflammatory cytokines, is associated with less cognitive impairment during chemotherapy. →