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When Compliance Workarounds Backfire
John Holcroft/Ikon Images In 2021, Barcelona-based delivery platform Glovo was faced with a law that threatened its business model. Spain had passed the Rider Law, which introduced a presumption of employment when a digital platform organizes, directs, or controls couriers’ work, including through algorithmic management. Glovo came up with what seemed like a clever fix… →
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Optogenetic Therapy for Restoring Aspects of Visual Function
CONCLUSIONS: Within the limits of this small study, intravitreal administration of a ChrimsonR-expressing AAV vector targeting retinal ganglion cells combined with use of light-stimulating goggles was safe. Additional research is needed to further assess safety and efficacy. (Funded by GenSight Biologics; PIONEER ClinicalTrials.gov number, NCT03326336.). →
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The Role of Biofeedback in Improving Vertigo Management in Older Adults. A Controlled Clinical Study in Italy
CONCLUSION: Despite these promising results, future research should delve deeper into the underlying mechanisms of vertigo in older persons, examining psychological factors and exploring potential correlations with other common comorbidities in this population, such as cardiovascular issues and cognitive decline. Understanding these interconnections will be crucial for developing more comprehensive and effective treatment strategies for… →
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The Acceptability and Experiences of Participating in a Preoperative Intentional Weight-Loss Programme From Diagnosis to Surgery for Colorectal Cancer
CONCLUSION: The weight-loss programme was mostly acceptable to people who had already joined the intervention. Addressing challenges with collective action may support more patients to adhere. →
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Immunogenicity, safety, and efficacy of rurioctocog alfa pegol in previously untreated patients with severe hemophilia A
CONCLUSION: These data demonstrate a low incidence of FVIII inhibitors among previously untreated patients receiving rurioctocog alfa pegol for severe hemophilia A. Efficacy and safety results were similar to prior reports in previously treated patients. →
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Intraoperative Dexmedetomidine and Postoperative Delirium After Head and Neck Cancer Surgery with Free-Flap Reconstruction: A Secondary Analysis of a Randomized Placebo-Controlled Trial
CONCLUSION: In patients undergoing head and neck cancer surgery with free-flap reconstruction, intraoperative dexmedetomidine infusion was associated with a lower incidence of postoperative delirium during the first 5 postoperative days, without an apparent increase in perioperative adverse events. →