CONCLUSION: Dutasteride 1 mg daily was efficacious in reducing the number of heavy drinking days and drinks per week in treatment-seeking men. The benefit of dutasteride compared with placebo was greatest for participants with elevated baseline drinking to cope motives. →
Background Anal cancer disproportionately affects sexual and gender minority individuals living with HIV. High-resolution anoscopy (HRA) is an in-clinic procedure to detect precancerous anal lesions and cancer, yet prospective data on factors associated with HRA attendance are lacking. We examined whether anal HPV sampling at home versus in a clinic impacts HRA uptake and assessed… →
Instant Voice Cloning (IVC) in Text-to-Speech (TTS) synthesis, also known as Zero-shot TTS, allows TTS models to replicate the voice of any given speaker with just a short audio sample without requiring additional training on that speaker. While existing methods like VALLE and XTTS can replicate tone color, they need more flexibility in controlling style… →
Physics-Informed Neural Networks (PINNs) have become a cornerstone in integrating deep learning with physical laws to solve complex differential equations, marking a significant advance in scientific computing and applied mathematics. These networks offer a novel methodology for encoding differential equations directly into the architecture of neural networks, ensuring that solutions adhere to the fundamental laws… →
The success of many reinforcement learning (RL) techniques relies on dense reward functions, but designing them can be difficult due to expertise requirements and trial and error. Sparse rewards, like binary task completion signals, are easier to obtain but pose challenges for RL algorithms, such as exploration. Consequently, the question emerges: Can dense reward functions… →