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New from Chinese Academy of Sciences: Stream-Omni, an LLM for Cross-Modal Real-Time AI
New from Chinese Academy of Sciences: Stream-Omni, an LLM for Cross-Modal Real-Time AI Understanding the Target Audience The primary audience for Stream-Omni includes AI researchers, business leaders in technology, and decision-makers in industries leveraging AI for multimodal applications. Their pain points often revolve around: Challenges in integrating diverse data modalities (text, vision, speech) Need for… →
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Announcing The Winners of the First Perception Challenge for Bin-Picking (BPC)
OpenCV and sponsors at Intrinsic, BOP, and University of Hawaiʻi at Mānoa are excited to announce the prize winners of the first Perception Challenge for Bin-Picking, first revealed at CVPR during the Perception for Industrial Robotics workshop. Beginning in February 2025, this challenge had over $60,000 at stake and over 450 teams vying for a… →
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Utility, Costs and Cost-Utility of Amyloid-PET in the Diagnostic Process of Memory Clinic Patients: A Trial-Based Economic Evaluation From AMYPAD-DPMS
CONCLUSION: Although patients receive an early etiological diagnosis, the cost-utility after 6 months is not favorable for amyloid-PET. The cost-utility will need to be reassessed when considering amyloid-PET to select patients for anti-amyloid biologics. →
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Combined prognostic impact of initial clinical stage and residual cancer burden after neoadjuvant systemic therapy in triple-negative and HER2-positive breast cancer: an analysis of the I-SPY2 randomized clinical trial
CONCLUSIONS: Tumor size at diagnosis remained an independent prognostic factor in patients with TNBC and HER2-positive breast cancer with RD after NAST. In contrast, patients achieving pCR had excellent outcomes regardless of initial disease extent, supporting the relevance of pCR as a surrogate endpoint in breast cancer. →
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Programmed death-1 inhibition increases vaccine-induced T-cell infiltration in patients with prostate cancer
CONCLUSION: Neoadjuvant PROSTVAC in combination with nivolumab is associated with increased intratumoral T-cell infiltrates, increased circulating tumor-associated antigen-specific T cells, and with radiographic and biochemical responses in the mCRPC setting. Our findings support the idea that the addition of a vaccine to a tumor-associated antigen might improve the clinical activity of immune checkpoint inhibition. →
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Ultrasound Measurement of Pupillary Dilation Reflex During Induction of General Anesthesia Using Sufentanil: A Randomized Controlled Trial
BACKGROUND Monitoring nociception is extraordinarily challenging during general anesthesia. This study aimed to observe pupillary dilation reflex by ultrasound and determine whether ultrasonic pupillary parameters are correlated with sufentanil dose during the induction period of general anesthesia. MATERIAL AND METHODS We enrolled 93 patients undergoing general anesthesia. They were randomly divided into 3 groups -… →
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Effects of combined diet and physical activity on glycemic control and body composition in male recreational athletes with type 2 diabetes mellitus
CONCLUSION: A combined therapeutic diet and physical activity program effectively improved body composition and biochemical parameters in recreational athletes with T2DM. This combined approach could be recommended as an integral strategy for diabetes management in physically active individuals. →
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The role of compounded mouthwash with or without acyclovir in managing chemotherapy-induced oral mucositis in cancer patients: a randomized controlled trial
CONCLUSIONS: The incorporation of acyclovir into compounded mouthwash significantly reduced the incidence, severity, and duration of oral mucositis in patients undergoing chemotherapy, indicating its potential for expanded clinical application. Further large-scale studies are warranted to validate these findings and to standardize mouthwash formulations for institutional utilization. →
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Evaluating Group CBT for Depression in Newly Diagnosed Breast Cancer Patients in a Malaysian Public Hospital
CONCLUSION: G-CBT significantly reduced depressive symptoms in newly diagnosed breast cancer patients and the effect of intervention sustains until third month follow-up. These findings emphasize the value of incorporating G-CBT into standard care practices to provide targeted psychological support and improve mental health outcomes in this vulnerable population. →
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Efficacy of losartan plus modified FOLFIRINOX versus modified FOLFIRINOX in advanced pancreatic cancers: A randomized clinical trial (AFPAC Study)
CONCLUSIONS: The addition of losartan to mFOLFIRINOX in the AFPAC study did not provide an early signal of efficacy in improving progression-free survival in advanced PDAC. The trial will not proceed to full accrual of phase 3 design. →