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Smartphone Cardiac Rehabilitation, Assisted Self-Management (SCRAM) Versus Usual Care: Multicenter Randomized Controlled Trial
CONCLUSIONS: This was an underpowered trial, but SCRAM did not lead to a clinically important difference in VO2max compared to usual cardiac care. SCRAM was resilient to COVID-19-related disruptions that significantly impacted the delivery of cardiac rehabilitation and supervised exercise training in particular. Further research is needed to conclusively assess treatment effects and understand how… →
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Effects of Self-Compassion and Mindfulness Interventions on Mental Health and Work-Related Outcomes Among Japanese Workers: Randomized Controlled Trial
CONCLUSIONS: This low-intensity, fully self-guided, smartphone-based meditation program demonstrated good feasibility, as reflected by high adherence and relatively low attrition. Between-group effects were limited; therefore, the findings should be interpreted as preliminary and do not support strong causal claims of intervention superiority. Clinical significance remains unclear in this nonclinical sample and should be evaluated in… →
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Integrating Large Language Models Into Trauma Education for Medical Students: Randomized Controlled Pilot Trial
CONCLUSIONS: While students appreciated the inclusion of artificial intelligence (AI), unstructured LLM use did not improve performance and may have disrupted the group reasoning. The use of non-English prompting likely contributed to lower AI performance, underscoring the importance of language alignment in LLM applications. This pilot study highlights the need for structured AI integration and… →
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Cold-Water Immersion Impairs Power Earlier than Strength Through Time-Dependent Reductions in Intramuscular Temperature in Human Dorsiflexor Muscles
CONCLUSIONS: These results highlight that peak power is more sensitive to reductions in intramuscular temperature than maximal isometric strength, reflecting a time- and temperature-dependent effect on skeletal muscle function. →
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Bridge the Intergenerational Leadership Gap
Carolyn Geason-Beissel/MIT SMR | Getty Images Today’s workforce spans five generations, with millennials and Generation Z together accounting for over 60% of workers globally — a share projected to reach 74% by 2030. Yet there’s a widening intergenerational gap in business leadership. While age diversity in the workplace is growing, decision-making power increasingly rests with… →
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What Wins When Anyone Can Build Anything with Brett Queener, Partner at Bonfire Ventures
The GTM Podcast is available on any major directory, including: Apple Podcasts Spotify YouTube Brett Queener (Partner at Bonfire Ventures) joins GTMnow to share what three decades across Siebel, early Salesforce, co-founding, and seed-stage investing has taught him about what actually wins now that software is cheaper and faster than he ever imagined. Brett was one… →
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A Novel Approach of Intraneural Facilitation Versus Standard Physical Therapy for the Prevention of Chemotherapy-Induced Peripheral Neuropathy: A Randomized Controlled Trial
This study compared Intraneural Facilitation (INF^(®)) therapy and standard physical therapy (PT) in preventing chemotherapy-induced peripheral neuropathy (CIPN) in women with newly diagnosed breast and gynecologic cancer. Thirty-eight women undergoing platinum and/or taxane-based chemotherapy, without prior peripheral neuropathy, were randomized into INF^(®) therapy (n = 20) and PT (n = 18). Treatments lasted 45 minutes,… →
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Cost-effectiveness of levonorgestrel intrauterine system versus hysteroscopic niche resection for caesarean scar-related spotting in China: an economic evaluation alongside a randomised controlled trial
CONCLUSIONS: LNG-IUS is highly cost-effective compared with HNR for the treatment of niche-related postmenstrual spotting at 6 months. These findings support LNG-IUS as first-line therapy for niche-related spotting in women with a residual myometrium ≥2.2 mm. →
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The breath and mind connection in young people with post-COVID syndrome: feasibility and acceptability of a pilot randomised co-designed intervention
Post-COVID syndrome is widely recognised in children and young people (CYP), where one or more persistent physical symptoms are present 12 weeks after the initial infection that cannot be explained by an alternative cause. We aimed to assess whether an intervention based on narrative therapy and breathing pattern retraining, co-designed with CYP with PCS (12-18… →
