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Enhancing Respiratory Support in COPD Patients with Nasal High Flow Using an Asymmetrical Cannula Interface: A Randomized Cross-Over Study
CONCLUSION: NHF reduced RR by shortening both inspiratory and expiratory times without altering the duty cycle. The lower MV during NHF with AI, accompanied by higher SpO(2), may indicate improved gas exchange efficiency. The use of AI could enhance the respiratory support effects of NHF in patients with advanced COPD. →
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How Schneider Electric Scales AI in Both Products and Processes
Matt Harrison Clough/Ikon Images At the World Economic Forum Annual Meeting in Davos, Switzerland, in January 2026, Schneider Electric CEO Olivier Blum accepted awards recognizing the company’s AI solutions as part of the WEF’s MINDS (Meaningful, Intelligent, Novel, Deployable Solutions) program — for the second time. The distinction highlighted two of the company’s AI-enabled applications:… →
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Reducing trauma-related parental stress in neurodevelopmental disorders: a randomized feasibility study
CONCLUSION: The EMDR-IGTP-OTS is a promising intervention for reducing trauma related parental stress symptoms in parents of children with NDDs. Its high feasibility makes it a suitable option for integration into clinical practice to support families facing trauma-related parenting challenges. →
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Trial of Edaravone for severe hypoxic ischemic encephalopathy in adults: a double-blind placebo-controlled study
CONCLUSION: Edaravone improved the short-term level of consciousness in severe HIE adult patients, but there was no significant effect on outcome and level of independence in performing activities of daily living. Further investigation into Edaravone’s effectiveness is warranted, particularly in patients with milder forms of HIE, as well as longer follow-up periods. →
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Integrated community-based versus facility-based care for people with HIV, diabetes, and hypertension in sub-Saharan Africa (INTE-COMM): an open-label, multicountry, cluster-randomised trial
BACKGROUND: In sub-Saharan Africa, the burden of diabetes and hypertension is high, alongside a high prevalence of HIV. Whether these conditions can be managed in an integrated way in the community is unknown. We aim to compare integrated community-based care with integrated facility-based care for people with HIV, diabetes, and hypertension in Tanzania and Uganda. →
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Effect of Nociceptors Hypostimulation Versus Nociceptors Hyperstimulation on Electromyography of Cervical Muscles, Myofascial Trigger Points Sensitivity, Pain, and Disability in Patients With Chronic Cervical Pain: A Randomized Double-Blinded Controlled Trial
BACKGROUND AND PURPOSE: Chronic cervical pain is a common disorder and is difficult to manage. Therefore, this study was conducted to investigate the effects of nociceptor hypostimulation versus hyperstimulation on electromyographic (EMG) activity of cervical muscles, myofascial trigger point (MTP) sensitivity, pain intensity, and disability in patients with chronic cervical pain. →
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Impact of Robotic Assisted Treadmill Gait Training on Walking Performance in Children With Spastic Diplegic Cerebral Palsy: A Randomized Controlled Study
BACKGROUND AND PURPOSE: Children diagnosed with diplegic cerebral palsy frequently experience gait difficulties that can significantly affect their independence and quality of life. The development of advanced technologies presents opportunities to enhance their walking abilities and overall functional performance. The purpose of this study was to determine how children with spastic diplegia performed when walking… →
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Efficacy and Safety of Vibegron Add-On Therapy for Persistent Overactive Bladder Symptoms in Benign Prostatic Hyperplasia Patients With α1-Blocker Treatment: A Multi-Center Prospective Randomized Controlled Study (VATON Study)
CONCLUSIONS: Vibegron add-on therapy to an α(1)-blocker may be effective and safe for treating BPH with persistent OAB symptoms. →
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Effect of Prebiotic Supplementation With and Without Physiotherapy on Pain and Pain Sensitivity in People with Knee Osteoarthritis
Background: Emerging evidence links the gut microbiome to chronic pain processing. Inulin, a prebiotic fibre, modulates the gut microbiome, while physiotherapy-supported exercise (PSE) improves pain and function. We evaluated the effects of inulin supplementation with and without PSE on knee osteoarthritis (OA) pain. Methods: In a 2 × 2 factorial RCT, 117 community-dwelling adults with… →
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Effect of a digital training package on clinical outcomes in Malawi’s index case testing programme: a cluster randomised controlled trial
CONCLUSIONS: Enhanced digital training positively impacted meaningful clinical outcomes and could be replicated for expansion to other evidence-based interventions. →
