CONCLUSIONS: The home-based DEP following Achilles tendon repair provided comparable clinical outcomes to traditional physiotherapy while significantly improving cost-effectiveness. These findings support the broader adoption of tele-supervised digital rehabilitation as a safe and effective alternative. →

CONCLUSIONS: The innovative patient education model integrating AI voice cloning and ChatGPT is distinct from previous studies primarily relying on standard text-to-speech or professionally recorded content. Using patients’ own cloned voices for health education delivery leveraged the self-reference effect to enhance learning outcomes. Compared with research using clinician-narrated content, this study highlights that self-voice education… →

CONCLUSION: The VISCIPH B pilot trial confirmed the feasibility, safety, and acceptance of supervised exercise for upper-extremity PNP in cancer patients. Significant improvements in patient-reported and functional outcomes indicate that combined sensorimotor and vibration exercise can meaningfully reduce PNP symptoms and should be evaluated in larger trials. →

CONCLUSIONS AND RELEVANCE: In this randomized clinical trial of patients undergoing diagnostic cerebral angiography, TRA was not shown to be noninferior to TFA with regard to the success rate of diagnostic cerebral angiography. Additional research, including superiority trials, is needed to clearly define the comparative benefits of TRA and TFA. →

CONCLUSION: In FIT-positive diagnostic colonoscopies with high baseline ADRs, AI assistance did not significantly improve lesion detection. Its primary utility lies in optimizing optical characterization by increasing specificity and PPV, suggesting a potential role in reducing false positives. Further multicentre studies incorporating cost-effectiveness analyses are warranted (ClinicalTrials.gov NCT07125300). →

CONCLUSION: Multi-strain probiotic supplementation did not enhance the metabolic efficacy of metformin in women with elevated HOMA-IR but significantly alleviated GI side effects. Probiotic co-administration may therefore improve tolerability and adherence to metformin therapy. →

CONCLUSIONS: Compared with fixed-field IMRT, HT provided superior dose distribution to the PTVs while maintaining a comparable incidence of RP in patients undergoing thoracic radiotherapy. →

CONCLUSION: Our findings can guide future efforts to implement and sustain patient navigation programs for follow-up colonoscopy after abnormal FIT testing in community-based settings. →