Drug-induced toxicity is a major challenge in drug development, contributing significantly to the failure of clinical trials. While efficacy issues account for most failures, safety concerns are the second leading cause, at 24%. Toxicities can affect various organ systems, including the heart, liver, kidneys, and lungs, and even approved drugs may face withdrawal due to… →
This study aimed to investigate the efficacy and safety of fire needle plus cupping (FC) combined with oral famciclovir and gabapentin for the treatment of acute-phase herpes zoster (AHZ). This study was conducted as a superiority, randomized controlled trial in which 84 patients with AHZ who met the diagnostic criteria were selected and randomly assigned… →
The ongoing advancement in artificial intelligence highlights a persistent challenge: balancing model size, efficiency, and performance. Larger models often deliver superior capabilities but require extensive computational resources, which can limit accessibility and practicality. For organizations and individuals without access to high-end infrastructure, deploying multimodal AI models that process diverse data types, such as text and… →
Language models (LMs) are advancing as tools for solving problems and as creators of synthetic data, playing a crucial role in enhancing AI capabilities. Synthetic data complements or replaces traditional manual annotation, offering scalable solutions for training models in domains such as mathematics, coding, and instruction-following. The ability of LMs to generate high-quality datasets ensures… →
Vision-Language Models (VLMs) allow machines to understand and reason about the visual world through natural language. These models have applications in image captioning, visual question answering, and multimodal reasoning. However, most models are designed and trained predominantly for high-resource languages, leaving substantial gaps in accessibility and usability for speakers of low-resource languages. This gap highlights… →
CONCLUSION: Mat Pilates classes for people with Parkinson’s with mild and moderate degrees proved to be effective in the short term in the hand grip strength of the right hand, and in the extension and flexion of the left legs, and positive effects in the long term in the strength of extension of the right… →
CONCLUSION: PT, when used in conjunction with conventional rehabilitation methods, significantly enhances motor function in children with CP. The study advocates for further extensive research to validate and understand the broader implications of PT in CP treatment. →
CONCLUSIONS: These preliminary findings suggest that a telemedicine-based approach to SARS-CoV-2 testing is feasible and could be integrated into existing hospital data infrastructures. This model has the potential for broader application in medical care, offering a scalable solution that could improve user satisfaction and treatment quality in the future. →