CONCLUSIONS: The trial will inform on the efficacy and safety of a synbiotic containing both aerobic and anerobic bacterial strains and a prebiotic fiber on reduction in bone loss and on indices of blood glucose regulation. This trial may pave the way for an exciting field of translational research and be the underpinnings of the… →
Respiratory symptoms are prevalent in the general population, and they are associated with a decline in lung function and increased mortality. The gut-lung connection suggests intestinal dysbiosis may impact lung diseases, with Akkermansia muciniphila showing promise in regulating extraintestinal diseases. However, its application in patients with respiratory symptoms lacks clinical trial evidence. In this randomized,… →
CONCLUSIONS: adding CGM feedback to INT resulted in better management of blood glucose levels in overweight or obese individuals with prediabetes. →
The advancements in large language models (LLMs) have created opportunities across industries, from automating content creation to improving scientific research. However, significant challenges remain. High-performing models are often proprietary, restricting transparency and access for researchers and developers. Open-source alternatives, while promising, frequently struggle with balancing computational efficiency and performance at scale. Furthermore, limited language diversity… →
Transformers have become the backbone of deep learning models for tasks requiring sequential data processing, such as natural language understanding, computer vision, and reinforcement learning. These models rely heavily on self-attention mechanisms, enabling them to capture complex relationships within input sequences. However, as tasks and models scale, the demand for longer context windows increases significantly.… →
CONCLUSIONS: While numbers in the current RCT were small and require further validation in larger cohorts, the results nevertheless suggest a molecular mechanism by which maternal folic acid supplementation during pregnancy may help to counteract the effects of folate depletion and positively influence cognitive development in the offspring. →
CONCLUSION: The intraoral injection technique might be an effective treatment modality for myofascial trigger points in the masseter muscle. It produces pain relief, increases mouth opening, and enhances the overall quality of life compared to the extraoral injection technique. →
Chemical synthesis is essential in developing new molecules for medical applications, materials science, and fine chemicals. This process, which involves planning chemical reactions to create desired target molecules, has traditionally relied on human expertise. Recent advancements have turned to computational methods to enhance the efficiency of retrosynthesis—working backward from a target molecule to determine the… →
While multimodal models (LMMs) have advanced significantly for text and image tasks, video-based models remain underdeveloped. Videos are inherently complex, combining spatial and temporal dimensions that demand more from computational resources. Existing methods often adapt image-based approaches directly or rely on uniform frame sampling, which poorly captures motion and temporal patterns. Moreover, training large-scale video… →