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AG-UI (Agent-User Interaction Protocol): An Open, Lightweight, Event-based Protocol that Standardizes How AI Agents Connect to Front-End Applications
The current generation of AI agents has made significant progress in automating backend tasks such as summarization, data migration, and scheduling. While effective, these agents typically operate behind the scenes—triggered by predefined workflows and returning results without user involvement. However, as AI applications become more interactive, a clear need has emerged for agents that can… →
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Microbiological Analysis of Lower Airway Samples: Does It Influence the Outcome in Patients With Community-Acquired Pneumonia?
This prospective randomized trial examined the impact of extensive lower respiratory tract sampling and microbial analysis on treatment decisions and patient outcomes in community-acquired pneumonia (CAP). One hundred and eighteen patients were randomized to rigorous sampling (intervention group, n = 64) or standard care (control group, n = 54). The primary outcome was antibiotic therapy… →
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Evaluation of parenting interventions for those with additional health and social care needs during pregnancy: THRIVE a multi-arm RCT with embedded economic and process components
CONCLUSIONS: With the population THRIVE involved, at a stage of pregnancy when a lot of support is offered (with many parenting interventions being offered without rigorous evaluation), we do not have evidence to recommend the rollout of Enhanced Triple P for Baby or Mellow Bumps. →
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Clinical and cost-effectiveness of lithium versus quetiapine augmentation for treatment-resistant depression in adults: LQD a pragmatic randomised controlled trial
CONCLUSIONS: As well as being more cost-effective, quetiapine may be a more clinically effective augmentation option for treatment-resistant depression. →
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Upadacitinib as monotherapy in patients with rheumatoid arthritis and prior inadequate response to methotrexate: results at 260 weeks from the SELECT-MONOTHERAPY randomised study
CONCLUSION: No new safety risks were identified with long-term UPA treatment. UPA monotherapy was efficacious in treating rheumatoid arthritis through week 260. →
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Tightly Coupled Range Inertial Odometry and Mapping with Exact Point Cloud Downsampling
This paper introduces a SLAM framework that achieves real-time CPU-only performance in dense, registration-error-minimization-based odometry and mapping by leveraging exact point cloud downsampling via coreset extraction, eliminating the need for GPU acceleration. Key Highlights Exact Point Cloud Downsampling via Coresets – Selects a minimal subset of residuals that exactly preserve the quadratic registration error function for a given pose,… →
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NVIDIA AI Introduces Audio-SDS: A Unified Diffusion-Based Framework for Prompt-Guided Audio Synthesis and Source Separation without Specialized Datasets
Audio diffusion models have achieved high-quality speech, music, and Foley sound synthesis, yet they predominantly excel at sample generation rather than parameter optimization. Tasks like physically informed impact sound generation or prompt-driven source separation require models that can adjust explicit, interpretable parameters under structural constraints. Score Distillation Sampling (SDS)—which has powered text-to-3D and image editing… →
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Reliability and usability of a portable spirometer compared to a laboratory spirometer
CONCLUSIONS: The portable spirometer exhibited a strong correlation and agreement with a high-quality laboratory spirometer, as well as concordance in spirometric abnormality diagnosis and severity classification. Non-specialist can obtain acceptable results using this portable spirometer. →
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The Reliability of a Novel Structured Testing Device for Single-breath Lung Carbon Monoxide Uptake: A Randomized Comparison Crossover Study
CONCLUSION: The MeHow MeAir 9000 spirometer provides high accuracy measurements of lung diffusing capacity and reliable assessment of the severity of diffusing capacity impairment, making it suitable for clinical use. →
