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Economic evaluation of a person-centred care intervention with a digital platform and structured telephone support for people with chronic heart failure and/or chronic obstructive pulmonary disease: results from a randomised controlled trial in Sweden
CONCLUSIONS: The results of this CEA demonstrated that a remote PCC add-on intervention for people with COPD and/or CHF had lower healthcare costs and higher health-related quality of life compared with usual care. →
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Microsoft Research Releases Skala: a Deep-Learning Exchange–Correlation Functional Targeting Hybrid-Level Accuracy at Semi-Local Cost
Microsoft Research Releases Skala: a Deep-Learning Exchange–Correlation Functional Targeting Hybrid-Level Accuracy at Semi-Local Cost Target Audience Analysis The primary audience for Skala includes researchers and professionals in computational chemistry and materials science, particularly those utilizing Kohn–Sham Density Functional Theory (DFT). This audience typically consists of: Academics and researchers focused on theoretical chemistry and materials science.… →
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Handle the Corporate Heat Like an Actual Firefighter
Carolyn Geason-Beissel/MIT SMR | Getty Images Picture this: You’re rappelling down the side of a burning building. Flames are everywhere. People are shouting for help. You look up to see who’s holding the rope — who’s keeping you from falling hundreds of feet to the concrete sidewalk below — and it’s … you, yourself! Feeling… →
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A feasibility study of an autonomy-supportive intervention in remote pulmonary rehabilitation for older adults with chronic obstructive pulmonary disease
CONCLUSION: An autonomy-supportive CIF intervention effectively enhanced autonomy support and maintained adherence in remote PR amongst older adults with COPD. →
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Intratumoral B cell and interferon signatures in newly diagnosed glioblastoma are associated with longer survival in patients treated with SurVaxM
Glioblastoma (GBM) has proved difficult to treat, and there is dire need for more effective therapies. In a single arm phase IIa trial (NCT02455557), treatment of newly diagnosed GBM patients with the peptide vaccine SurVaxM resulted in promising median progression-free and overall survival. To investigate molecular features that associate with GBM responsiveness to SurVaxM, retrospective… →
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Tiny Recursive Model (TRM): A Tiny 7M Model that Surpass DeepSeek-R1, Gemini 2.5 pro, and o3-mini at Reasoning on both ARG-AGI 1 and ARC-AGI 2
«`html Understanding the Tiny Recursive Model (TRM) The Tiny Recursive Model (TRM) is a compact 7M-parameter model developed by Samsung SAIT (Montreal) that demonstrates superior reasoning capabilities compared to larger models such as DeepSeek-R1, Gemini 2.5 Pro, and o3-mini on both ARC-AGI 1 and ARC-AGI 2 benchmarks. TRM achieves a test accuracy of 44.6–45% on… →
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Comparative analysis of neutralization assays performed using live SARS-CoV-2 virus and pseudovirus to assess immunogenicity of a bivalent SARS-CoV-2 protein vaccine in humans
CONCLUSIONS: Our findings demonstrate a strong correlation between PVNA and LVNA results, supporting PVNA as a safe, scalable, and reliable surrogate for LVNA in evaluating vaccine immunogenicity. →
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The effectiveness of radial extracorporeal shock wave therapy (rESWT) in plantar fasciitis: a 12 months randomised controlled trial in a Tunisian rehabilitation department
CONCLUSION: Both protocols (rESWT and physiotherapy combined to ultrasound) were effective for improving morning pain at short term and midterm follow-up periods. Foot disorders should be initially evaluated and considered while treating. →
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Enhanced external counter pulsation as a novel therapy to maintain cardiac output during hemodialysis: a preliminary randomized controlled study
Intradialytic cardiac output (CO) decline normally occurs during hemodialysis (HD) and results in short-term intradialytic hypotension to longer-term increased cardiovascular morbidity and mortality in chronic HD patients. Enhanced external counter pulsation (EECP) is a novel non-invasive device that has been demonstrated to improve coronary blood flow and maintain systemic hemodynamics in patients without kidney dysfunction.… →