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  • Diaphragmatic ultrasound and thoracic fluid content for prediction of non-invasive ventilation failure in neonates: a randomized controlled trial

    9 декабря, 2025

    CONCLUSIONS: Diaphragmatic ultrasound and TFC-derived EC represent simple, non-invasive, and reliable tools for predicting NIV failure in preterms with RDS. →

    Clinical Trials
  • (61)Cu-NODAGA Prostate-specific Membrane Antigen Imaging and Therapy for Prostate Cancer: Phase 1 Trial of a New Class of (61)Cu-labeled PET Radiotracers

    9 декабря, 2025

    Background Prostate-specific membrane antigen (PSMA)-targeted PET has revolutionized prostate cancer imaging, but the sensitivity at low prostate-specific antigen levels is lacking. Copper 61 (^(61)Cu) is a positron emitter with favorable physical characteristics that allow for delayed imaging, which may result in improved sensitivity. Purpose To evaluate the safety, dosimetry, optimal imaging parameters, and initial efficacy… →

    Clinical Trials
  • Effect of Insulin Sensitizers on Glycemic and Lipid Profile in Patients with Polycystic Ovary Syndrome (PCOS)

    9 декабря, 2025

    Introduction: Polycystic ovary syndrome (PCOS) is associated with increased cardiovascular risk later in life. Insulin resistance, common in PCOS, heightens the risk of type 2 diabetes, dyslipidemia, hypertension, and cardiovascular disease. This study explored whether insulin sensitizers could modify traditional cardiovascular risk factors, through influence on insulin resistance. Objectives: To evaluate the impact of Metformin… →

    Clinical Trials
  • Christmas article: Alcohol induced rhinitis

    9 декабря, 2025

    CONCLUSION: Beer may provoke transient nasal congestion more than wine, although the difference was not statistically significant. Findings support the hypothesis that some Christmas »sniffles« may be alcohol-related rather than viral. →

    Clinical Trials
  • CRM apps for small teams that scale with you as you grow

    9 декабря, 2025

    For small businesses and sales teams, staying connected to customers doesn’t always happen behind a desk. Conversations, deals, and follow-ups unfold on calls, in meetings, and on the road — making a mobile-ready CRM essential for modern workflows. A mobile CRM app puts the entire customer pipeline in reps’ pockets. It gives teams instant access… →

    AI Sales
    AI, Analytics, B2BMarketing, B2BSales, BrandStrategy, ContentMarketing, ConversionOptimization, CustomerExperience, DataDriven, DigitalMarketing, Ecommerce, GrowthHacking, InboundMarketing, LeadGeneration, MarketingAutomation, MarketingTips, Salesforce, SEO, SocialSelling, TechnologyTrends
  • Preventive Effect of Shenfu Injection on Arrhythmia After Percutaneous Coronary Intervention in Patients With ST-Segment Elevation Myocardial Infarction: A Prospective Randomized Controlled Trial

    9 декабря, 2025

    CONCLUSIONS: Treatment with Shenfu injection as an adjunctive therapy to standard treatment in patients with STEMI undergoing PCI significantly reduced in-hospital arrhythmias, infarct size, microvascular obstruction, and major adverse cardiac events during a 12-month follow-up period. The independent effect on arrhythmias after comprehensive statistical adjustment and the demonstrated correlation between reduced myocardial damage and arrhythmia… →

    Clinical Trials
  • Nudging Emergency Department Clinicians to Reduce Unnecessary Diagnostic Test Ordering: A Multi-Arm Vignette-Based Experiment

    9 декабря, 2025

    CONCLUSION: While potentially of limited value for reducing the total number of tests ordered, nudge-based clinical decision support interventions that manipulate decision structure and employ decision assistance may reduce tests other than FBE and U&E in emergency departments, especially among less experienced clinicians. →

    Clinical Trials
  • Enhanced Eustachian Tube Function and Hearing Recovery with Combined Balloon Dilatation and Tympanic Membrane Catheterization in Secretory Otitis Media

    9 декабря, 2025

    BACKGROUND Secretory otitis media (SOM), a common otorhinolaryngological disorder, impairs hearing and quality of life. Eustachian tube balloon dilatation (ETBD) is increasingly used, and its combination with tympanic membrane catheterization (TMC) may enhance outcomes. This study compared ETBD alone with ETBD combined with TMC in adult SOM. MATERIAL AND METHODS Ninety patients (110 ears) with… →

    Clinical Trials
  • A Phase II Pilot Study of Anti-PD-L1, Durvalumab, and a PARP Inhibitor, Olaparib in Patients With Metastatic Triple-Negative Breast Cancer With or Without Germline BRCA Mutation

    9 декабря, 2025

    CONCLUSION: Our study demonstrated modest clinical benefits of D + O with ORR of 28.6% in subsets of heavily pretreated TNBC. Further detailed classification of DCs to understand the predictive role of DCs and prospective validation in a large cohort is required. →

    Clinical Trials
  • Virtual Standardized Patients for Improving Clinical Thinking Ability Training in Residents: Randomized Controlled Trial

    9 декабря, 2025

    CONCLUSIONS: VSPs reinforce the foundational knowledge of internal medicine among medical students and enhance their clinical thinking abilities, as well as improve their capacity for independent work. The VSP system is feasible, practical, and cost-effective, making it worthy of further promotion in clinical education. →

    Clinical Trials
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