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A Coding Guide to Build a Fully Functional Multi-Agent Marketplace Using uAgent
A Coding Guide to Build a Fully Functional Multi-Agent Marketplace Using uAgent A Coding Guide to Build a Fully Functional Multi-Agent Marketplace Using uAgent In this tutorial, we explore how to build a small yet functional multi-agent system using the uAgents framework. We set up three agents — Directory, Seller, and Buyer — that communicate… →
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Effect of orally administered L. crispatus M247 in favoring HR-HPV clearance and CST shift: results from a randomized, multi-center, placebo-controlled trial
Epidemiological evidence support the idea that CST I, L. crispatus-dominated vaginal microbiota, could protect women form cervical HPV infection also favoring the HPV clearance. Our prospective, multi-center, randomized, placebo-controlled trial on 62 women newly diagnosed of HPV infection without visible cervical lesions at colposcopy, was mainly aimed at evaluating the role exerted by the oral… →
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Effects of melatonin on advanced glycation end products, inflammation, and oxidative stress in peritoneal dialysis patients: a randomized controlled trial
Advanced glycation end products, systemic and vascular inflammation, and oxidative stress are risk factors for cardiovascular disease in peritoneal dialysis (PD) patients. No studies have examined the effects of melatonin on these risk factors in PD patients. This study was a randomized clinical trial. Forty-four PD patients were randomly assigned to either the melatonin or… →
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Proactive Identification and Digital Mental Health Intervention for the Treatment of Depression Among Individuals With Likely Incurable Cancer: A Pilot Randomized Clinical Trial
CONCLUSIONS: A proactive ID + DMHI approach to identifying and treating depression among ILLIC is feasible, acceptable, and potentially efficacious. These promising data support conducting a large efficacy trial evaluating this approach. →
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Sustained resolution of enthesitis and peripheral arthritis over 104 weeks with bimekizumab in axial spondyloarthritis
CONCLUSION: BKZ resulted in sustained improvements in peripheral manifestations to 2 years across the full disease spectrum of axSpA. →
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Changes in frailty based on minimally important difference and the impact of spironolactone on frailty in heart failure with preserved ejection fraction: insights from the TOPCAT trial
CONCLUSIONS: Frailty improvement exceeding the 0.03 FI threshold predicts better prognosis in HFpEF, underscoring the value of routine assessment. Spironolactone use was associated with neutral effects on frailty progression in our analysis, suggesting potential safety in this vulnerable population. →
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Reduced Chronic Obstructive Pulmonary Disease-Related Utilization of Health Care Services and Increased Social Activities by Patients Offered a 24/7 Accessible Telehealth Service Based on the Epital Care Model: Pragmatic Modified Stepped Wedge Randomized Controlled Trial
CONCLUSIONS: These results contribute to a new perspective on how health care services can be organized to reduce health care usage and increase social activity and mobility based on an ECTHS manned with nonprofessional certified staff. →
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Anthrogen Introduces Odyssey: A 102B Parameter Protein Language Model that Replaces Attention with Consensus and Trains with Discrete Diffusion
Anthrogen Introduces Odyssey: A 102B Parameter Protein Language Model Target Audience Analysis The target audience for Anthrogen’s Odyssey model includes researchers and professionals in the fields of bioinformatics, computational biology, and protein engineering. This audience typically faces several pain points, including: Difficulty in designing proteins that accurately represent their sequence and structure under functional constraints.… →
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Surprise: Corporate Sustainability Isn’t Dead
Fabien Gilbert/Ikon Images Every year, timed to coincide with the UN General Assembly meeting — apparently to ensure maximum traffic jams — thousands of people descend on New York City to talk climate. A series of over 1,000 events all across Manhattan, under the banner of Climate Week, gives a snapshot of where we are… →
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PokeeResearch-7B: An Open 7B Deep-Research Agent Trained with Reinforcement Learning from AI Feedback (RLAIF) and a Robust Reasoning Scaffold
«`html PokeeResearch-7B: An Open 7B Deep-Research Agent Trained with Reinforcement Learning from AI Feedback (RLAIF) and a Robust Reasoning Scaffold Target Audience Analysis The target audience for PokeeResearch-7B consists of AI researchers, business managers, and data analysts who are interested in leveraging advanced AI technologies for deep research tasks. Their pain points include the need… →