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Lessons from Vercel’s COO
As an operator who scaled both Google and Stripe for a decade each before joining Vercel, Jeanne Dewitt-Grosser’s insights bridge the gap between “traditional” best practices and the future of “vibe-coding” and AI agents. After sitting down with Jeanne to unpack her scaling philosophy, we’ve distilled four core lessons: Lesson 1: Treat go-to-market as a… →
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Impact of Contrast Volume Used After Percutaneous Coronary Procedures in Patients at Risk for Contrast-Induced Nephropathy
CONCLUSION: The type of contrast was not associated with CIN, even among patients exposed to higher contrast volumes. →
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Presenting symptoms and diagnostic accuracy of prehospital stroke scales for patients with suspected mild minor stroke
CONCLUSIONS: In patients with mild minor stroke, substantial overlap in presentation between stroke and stroke mimics makes triage challenging. Prehospital stroke scales provide either high sensitivity or specificity. Competence and training of paramedics in when and how to use, and interpret, these scales is key for recognizing and correctly triaging stroke patients.The ParaNASPP trial was… →
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Pre-hospital treatment duration and efficacy of remote ischaemic conditioning in the RESIST randomised-controlled trial
CONCLUSION: Longer pre-hospital treatment duration was not associated with efficacy of RIC in the RESIST trial including in patients with AIS who received reperfusion therapies. Findings may not apply to settings where RIC could be routinely administered for longer periods. We found no treatment duration-dependent benefit of pre-hospital RIC, at least when durations are under… →
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Randomised, controlled Trial of CT perfusion and angiography compared to CT alone in thrombolysis-eligible acute ischaemic stroke patients: The penumbra and recanalisation acute computed tomography in ischaemic stroke evaluation (PRACTISE) trial
CONCLUSION: Among acute stroke patients imaged <4.5 h from symptom onset, multimodal CT reduced use of thrombolysis. Treatment decision times and clinical outcomes did not differ between groups. →
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Safety and efficacy of intra-arterial tenecteplase for non-complete reperfusion of intracranial occlusions: Methodology of a randomized, controlled, multicenter study
RATIONALE: Intra-arterial fibrinolytics may be used for distal remaining vessel occlusions after incomplete mechanical thrombectomy (MT). However, their efficacy in improving reperfusion in this specific clinical scenario is unclear. While better reperfusion may lead to improved clinical outcomes, additional fibrinolytics could also increase the risk of hemorrhagic complications. →
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Corticomotor Excitability Changes Induced by Progressive Balance Exercises in Chronic Ankle Instability: a Randomized Clinical Trial
CONCLUSIONS: Six weeks of progressive balance exercises significantly increased corticomotor excitability corresponding to the peroneus longus muscle in individuals with chronic ankle instability. →
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Ivarmacitinib in patients with moderate to severe atopic dermatitis stratified by baseline characteristics: a post-hoc analysis of a phase 3 clinical trial
CONCLUSION: Ivarmacitinib demonstrated efficacy and good tolerability in treating moderate to severe AD with diverse patient characteristics. →
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From awareness to action: Health Belief Model-based educational intervention to improve breast self-examination practice among college teachers in Pakistan (CRCT)
CONCLUSION: HBM-based intervention effectively enhanced BSE knowledge, beliefs, and practices while reducing barriers. Findings emphasize the value of structured educational interventions in promoting preventive health behaviors among female educators. →
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How to Use Generative AI for Pricing
Matt Harrison Clough/Ikon Images How can recent advances in generative AI tools be applied to transform pricing decisions? By lowering technical and financial barriers, such tools democratize access to sophisticated pricing capabilities, empowering even small businesses to benefit from artificial intelligence without the need for costly, bespoke solutions. There are fundamental differences between GenAI-driven approaches… →