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  • Results of the observational program CITOTREK (use of the drug CITOflavin in Tablets) in patients with tension headaches against the backgRound of asthenic syndromE taKing into account comorbidity

    19 ноября, 2025

    CONCLUSION: The results of the study allow us to consider the drug Cytoflavin in the treatment regimens for comorbid patients with TTH in asthenic disorders. →

    Clinical Trials
  • Impact of TauroLock™-HEP500 versus unfractionated heparin for prevention of catheter complications in children with malignancy: a prospective, randomized, controlled study

    19 ноября, 2025

    CONCLUSION: Taurolidine-citrate exhibited a modest anti-inflammatory effect, reflected by reduced hs-CRP and WBC levels, without significant improvement in catheter-related complications or IL-6. The lack of major clinical benefit may relate to the heterogeneous and immunocompromised nature of pediatric oncology patients. Larger, adequately powered studies are warranted to clarify the long-term efficacy and safety of taurolidine-citrate… →

    Clinical Trials
  • Sociodemographic characteristics of patients throughout the recruitment process into a randomized, controlled behavioral trial

    19 ноября, 2025

    CONCLUSIONS: Following a recruitment process of patients identified in the EHR, people with diabetes, males, Hispanics, and Spanish speakers were less likely to participate in a physical activity behavior trial for patients with diabetes or prediabetes, with no apparent differences in neighborhood deprivation. →

    Clinical Trials
  • Comparison of the influence of 1% and 0.01% atropine on the corneal topography in myopic children

    19 ноября, 2025

    CONCLUSION: We found that 1% or 0.01% atropine had a minor impact on the corneal topography. Longitudinal alterations in corneal geometry are predominantly ascribable to physiological ocular growth and myopic progression rather than to atropine exposure. →

    Clinical Trials
  • Eicosapentaenoic acid decreases inflammation and improves glucose homeostasis in patients with burns: a randomized clinical trial

    19 ноября, 2025

    Burn is accompanied by metabolic changes. The effects of fish oil on inflammatory pathways and glucose homeostasis have been reported in the previous studies. Various forms of omega-3 fatty acids affect differently the metabolic pathways. The present study was designed to investigate the effects of fish oil containing 500 mg eicosapentanoic acid (EPA) on inflammatory… →

    Clinical Trials
  • Higher PEEP reduces duration of mechanical ventilation in neonatal respiratory distress syndrome of late preterm and term newborn infants

    19 ноября, 2025

    Mechanical ventilation was frequently conducted in late preterm and term newborn infants because of their severity of neonatal respiratory distress syndrome (NRDS), but the level of positive end expiratory pressure (PEEP) used was not explicit. This study aimed to investigate the efficacy and safety of higher-PEEP in the treatment of NRDS in these infants. Initially,… →

    Clinical Trials
  • The Forces That Shape AI’s Uneven Progress

    19 ноября, 2025

    Dan Page/theispot.com As artificial intelligence has begun to write code, pilot vehicles, and even diagnose disease, narratives of machines abruptly replacing humans have taken hold. However, the real story is slower, messier, and far more uneven. Across roles and industries, AI’s emergent capabilities form what’s often called a “jagged frontier,” where it excels at some… →

    Management
  • Impact of Culturally Sensitive AIDS Video Education on The AIDS Risk Knowledge of African-American Adolescents

    19 ноября, 2025

    AIDS video education is a major mode of providing information about the spread and prevention of the human immunodeficiency virus (HIV). Very little has been written about the need for culturally salient messages in increasing the acquisition and retention of HIV/AIDS prevention information, even though there is considerable agreement that limited culturally sensitive information is… →

    Clinical Trials
  • The Effects of a Multidomain Lifestyle Intervention on Brain Function and Its Relation With Immunometabolic Markers and Intestinal Health in Older Adults at Risk of Cognitive Decline: Study Design and Baseline Characteristics of the HELI Randomized Controlled Trial

    19 ноября, 2025

    CONCLUSIONS: The HELI study aims to enhance our understanding of the working mechanisms of multidomain lifestyle interventions through its comprehensive characterization of central and peripheral markers. We intend to achieve this aim by assessing lifestyle intervention-induced changes in functional and structural MRI brain measures, as well as peripheral measures of the gut-immune-brain axis involved in… →

    Clinical Trials
  • Effects of narrative nursing on delirium and outcomes in mechanically ventilated ICU patients: a randomized trial

    18 ноября, 2025

    CONCLUSION: A structured narrative nursing intervention reduced the incidence and duration of delirium among mechanically ventilated ICU patients, improved selected clinical outcomes, and increased patient satisfaction. Limitations include the single-center design, modest sample size, and limited blinding, which may introduce bias. Multicenter, adequately powered, prospectively registered randomized trials are warranted to confirm these findings. →

    Clinical Trials
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