Coronary CT angiography (CCTA) in obese patients is challenging due to high radiation exposure, elevated iodine load, and increased image noise. We evaluated a tripartite low-dose strategy combining high-iodine-concentration contrast media (HCM, 400 mgI/mL), 80-kVp scanning, and deep learning image reconstruction (DLIR) in obese patients (BMI ≥30 kg/m2) to simultaneously reduce radiation and iodine dose… →

CONCLUSIONS: Under free-living conditions, the personalized exercise prescription based on CST effectively reduced glycemic variability in T2D patients. →

CONCLUSION: The intervention reduced patient costs and improved outcomes across SES groups. Decentralised TB testing with the Molbio Truenat platform is both cost-saving and more effective and cost-effective compared with a hub-and-spoke model in Mozambique and Tanzania. →

CONCLUSIONS: Our findings suggest that app-guided exposure therapy can be a useful further treatment option in addition to established psychological and pharmacological strategies. However, superiority compared to the disorder-unspecific meditation app remains unclear. →

This study assessed the potential risk of QT prolongation associated with the dual enhancer of zeste homolog 1/2 inhibitor valemetostat. An evaluation of the relationship between plasma valemetostat concentration and heart-rate-corrected QT (QTc) interval was performed. Time-matched plasma concentration and 12-lead electrocardiogram data were collected from the phase I studies DS3201-A-J101, in patients with relapsed/refractory… →

CONCLUSION: The results showed that the use of TPB contributed to the improvement of self-care for knee osteoarthritis in older people. Due to the importance of health education in promoting self-care behaviors and preventing complications, longer interventions with the aim of preventing the complications of knee osteoarthritis in older people are suggested. →

This study investigates the efficacy and economic efficiency of augmented-reality (AR)-enhanced health-media campaigns in urban settings of Jordan, the Saudi Arabia. Employing a quasi-experimental, comparative design, 600 adults aged 18-45 were randomly assigned to either an AR intervention-featuring interactive 3D simulations of smoking risks and vaccination mechanisms-or a conventional video/text campaign. Pre- and post-intervention surveys… →