CONCLUSIONS: Treatment with upadacitinib demonstrated consistent improvement and maintenance of treatment effect across efficacy endpoints through 2 years; no new safety signals were identified with additional exposure. →
CONCLUSION: Understanding the needs of youth experiencing homelessness who are at risk for suicide is critical to developing interventions to alleviate their risk for suicide. Given that the use of medical and mental health care is low among this population, more active outreach strategies may be warranted to deliver prevention interventions. →
BACKGROUND: Patients with advanced gastric cancer (AGC) have poor survival after first-line treatment containing an anti-programmed death-1/ligand 1 (PD-1/PD-L1) antibody. Accumulating evidence suggests rationales for continuing immunotherapy beyond progression, synergistic effects between immune checkpoint inhibitors and angiogenesis inhibitors, and a preferable combination of steroid-free chemotherapy with immunotherapy. These rationales imply that nanoparticle albumin-bound (nab)-paclitaxel… →
As we step into 2025, open-source projects continue to set new benchmarks in innovation and accessibility. This January, several GitHub repositories have emerged as trendsetters, ranging from personal AI assistants to advanced web automation tools and collaborative knowledge platforms. These projects highlight the incredible potential of community-driven development to solve real-world challenges. PROJECT #1 STORM:… →
CONCLUSIONS: Impaired left ventricular diastolic function, measured using tissue Doppler echocardiography through e’ and E/e’, independently predicts increased cardiovascular mortality over 20 years in hypertensive patients, highlighting its long-term prognostic significance. →
Despite recent advancements, generative video models still struggle to represent motion realistically. Many existing models focus primarily on pixel-level reconstruction, often leading to inconsistencies in motion coherence. These shortcomings manifest as unrealistic physics, missing frames, or distortions in complex motion sequences. For example, models may struggle with depicting rotational movements or dynamic actions like gymnastics… →
In our previous tutorial, we built an AI agent capable of answering queries by surfing the web and added persistence to maintain state. However, in many scenarios, you may want to put a human in the loop to monitor and approve the agent’s actions. This can be easily accomplished with LangGraph. Let’s explore how this… →
Graph Neural Networks (GNNs) have found applications in various domains, such as natural language processing, social network analysis, recommendation systems, etc. Due to its widespread usage, improving the defences of GNNs has emerged as a critical challenge. While exploring the mechanisms vulnerable to an attack, researchers came across Bit Flip Attacks (BFAs). Conventionally, BFAs were… →
Despite progress in AI-driven human animation, existing models often face limitations in motion realism, adaptability, and scalability. Many models struggle to generate fluid body movements and rely on filtered training datasets, restricting their ability to handle varied scenarios. Facial animation has seen improvements, but full-body animations remain challenging due to inconsistencies in gesture accuracy and… →
This randomized clinical trial aimed to evaluate the effect of selective caries removal in deep Class I cavities in posterior teeth followed or not by photobiomodulation (PBM) therapy at two different wavelengths on postoperative sensitivity. Baseline spontaneous and stimulated sensitivity scores of 33 vital permanent molars were determined by the participants using a numeric rating… →