BACKGROUND: Disorders of gut-brain interaction (DGBIs) affect approximately 25% of children worldwide and account for a substantial proportion of paediatric gastroenterology consultations. These conditions are associated with significant morbidity, including chronic pain, school absenteeism, anxiety and reduced quality of life. Current treatment options offer limited efficacy, particularly in paediatric populations. Acupuncture, a widely used complementary… →

CONCLUSIONS: In this randomized, high-difficulty simulation study, real-time, voice-based AI assistance was associated with higher physician Top-3 diagnostic accuracy than an unassisted, resource-restricted comparator. Some sensitivity analyses were supportive, while others were directionally favorable but inconclusive, and the safety analysis suggested possible overreliance without statistically conclusive difference between conditions. These findings support further refinement and… →

CONCLUSIONS: This study will provide insights into the potential added value of a digital reminder tool for T2DM management in a real-world setting as well as the usability and acceptability of this tool. →

CONCLUSION: FR-A had consistently lower adjusted reaction time than FR-B across all scoring methods. However, the FR-A-control comparison depended on baseline reaction time and scoring method. Thus, the findings do not establish a scoring-independent benefit of the 30-second protocol over passive rest or support a firm practical recommendation. →

CONCLUSION: Liquorice intake did not improve metabolic markers but attenuated hsCRP elevation. The potential metabolic benefits of glabridin are unlikely to outweigh the hypertensive effects when consumed as whole liquorice. →

Rural populations often face structural barriers to accessing, interpreting, and using health information, contributing to persistent health literacy disparities. This cluster randomized controlled trial evaluated whether a theory of planned behavior-based intervention could improve health literacy acquisition behaviors and overall health literacy among rural residents in Changzhou, China. Twenty villages were randomized to a 12-month… →

CONCLUSIONS: Both GH and SFRC-supported microhybrid composite restorations provided clinically acceptable long-term outcomes in MIH-affected molars after SCR. Although clinical performance per modified USPHS criteria was comparable, SFRC-supported microhybrid composite restorations demonstrated superior long-term survival. →

To compare the clinical efficacy of erbium, chromium-doped yttrium scandium gallium garnet (Er, Cr: YSGG) laser versus conventional air-rotor handpiece for caries removal in primary teeth and their effects on children’s anxiety and pain levels, to provide evidence for optimizing pediatric dental treatment. A total of 90 children (aged 6-10 years) with primary tooth caries… →

Adhering to the latest fashion trends may be an unwritten social expectation in many educational and business contexts. However, Dr Dorottya Sallai argues that the detrimental impact fast fashion causes to the environment goes far beyond the benefits it offers. When people update their wardrobes every season, they may not realise that the manufacturing of just one simple cotton T-shirt requires approximately 2,700 litres of water. However, hyper-consumption of fast fashion continues. Would behaviours… →
Matt Harrison Clough/Ikon Images In an unpredictable economy and fractured media landscape, marketing leaders are navigating a period of profound transformation and disruption — and as AI technologies evolve, the pace of change will only increase. In response, the highest priorities of chief marketing officers today are shifting, and understanding their concerns is essential to… →