BACKGROUND: Brucellosis is a common zoonotic disease and a significant public health concern. Effective health management is essential for improving the self-management behaviors of brucellosis patients. This study aims to assess the effectiveness of a mobile health (mHealth) intervention based on the Health Action Process Approach (HAPA) model in enhancing self-management among brucellosis patients. →

CONCLUSION: Compared to men, PVI-only in women with persistent AF leads to a significantly lower freedom from atrial arrhythmia. A personalised spatio-temporal dispersion-targeted ablation strategy led to a higher rate of freedom from any atrial arrhythmia than standard PVI after a single procedure in women and comparable outcomes between women and men. →

CONCLUSIONS: A higher early postnatal ETCOc is linked with an increased risk of PT and PT characteristics within 7 DOLs. Early postnatal ETCOc can be a valuable indicator for predicting PT in early postnatal period. →

Cognitive impairments have been observed in patients with depression. These include deficits in inhibition, shifting, and updating; cognitive processes that are critical for goal-directed control over behavior (‘model-based planning’). Nevertheless, results of model-based planning in depression have been mixed. We aimed to address this by taking a within-person approach, examining model-based planning before and after… →

BACKGROUND: Brain-infiltrating tumour cells from high-grade glioma remain shielded from drug treatments by the blood-brain barrier, leading to inevitable recurrence. Microbubble-enhanced transcranial focused ultrasound (MB-FUS) enables controlled blood-brain barrier opening (BBBO), permitting localised drug delivery. We aimed to assess safety and feasibility of MB-FUS plus standard-of-care chemotherapy for individuals with high-grade glioma. →

To investigate the effects of heavy-load strength training during (neo-)adjuvant chemotherapy on cardiorespiratory fitness and muscle content of aerobic enzymes and capillaries, as well as to explore its effects on cancer-related fatigue and health-related quality of life (HR-QoL) in women with breast cancer. Women diagnosed with stage I-III breast cancer were randomized to a strength… →

This was a nonblinded randomised controlled trial comparing pharmacist-led hepatitis C virus (HCV) treatment in the community, to tertiary care hepatology. Of 34 antibody-positive individuals, 28 completed a rapid HCV RNA test in the pharmacy. The study was terminated after randomising 11 participants over 15 months (recruitment continued until ~27 months), as a result of… →

CONCLUSION: NIRI showed superior performance in early caries detection. Compared to panoramic radiography, NIRI is more sensitive and avoids ionizing radiation, making it safer and more comfortable. Its reliability and patient-friendly nature support its use as a promising tool in routine preventive dental care. →

CONCLUSION: In patients undergoing CAPD, the coexistence of pre-existing cardiovascular disease and hyperlipidemia is associated with a significantly higher risk of all-cause mortality. This finding suggests that the comorbidity may contribute to worse long-term outcomes and highlights the importance of dyslipidemia management in clinical practice. →

This study evaluates the clinical efficacy and biomarker effects of quetiapine combined with magnesium valproate in patients with schizophrenia. A total of 156 patients diagnosed with schizophrenia were randomly assigned to 2 groups: 1 received magnesium valproate monotherapy (n = 78), and the other received combined therapy with quetiapine and magnesium valproate (n = 78).… →