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Early Change in Depressive Symptom Severity With Naltrexone-Bupropion Combination and Its Association With Reduction in Methamphetamine Use in ADAPT-2 Trial
Objective: This study evaluated whether depressive symptom severity improved early with extended-release naltrexone and bupropion combination (naltrexone bupropion) compared to a placebo in individuals with moderate/severe methamphetamine use disorder and predicted subsequent use of methamphetamine. →
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Mom Supporting Mom: Effective Peer Support Intervention for Women with Postpartum Psychological Distress
Objective: Untreated perinatal mental health disorders can have serious consequences for the whole family system. The purpose of this study was to examine the effectiveness of peer support intervention in improving postpartum psychological distress. Method: We evaluated a remote peer support intervention, Mom Supports Mom, in a randomized controlled trial. The primary study outcome was… →
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Efficiency of remote monitoring and guidance in blood pressure management: a randomized controlled trial : The role of remote monitoring in improving hypertension management
CONCLUSIONS: Remote monitoring and guidance enhanced the efficiency of BP management, whereas self-monitoring alone proved to be ineffective. →
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Model Context Protocol (MCP) FAQs: Everything You Need to Know in 2025
«`html Model Context Protocol (MCP) FAQs: Everything You Need to Know in 2025 The Model Context Protocol (MCP) has rapidly become a foundational standard for connecting large language models (LLMs) and other AI applications with the systems and data they need to be genuinely useful. In 2025, MCP is widely adopted, reshaping how enterprises, developers,… →
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This AI Paper Introduces C3: A Bilingual Benchmark Dataset and Evaluation Framework for Complex Spoken Dialogue Modeling
This AI Paper Introduces C3: A Bilingual Benchmark Dataset and Evaluation Framework for Complex Spoken Dialogue Modeling Understanding the Target Audience The primary audience for this research includes AI researchers, business analysts, and product managers involved in developing and evaluating conversational AI systems. Their key pain points include: Challenges in evaluating the performance of Spoken… →
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A Coding Implementation to Build a Self-Adaptive Goal-Oriented AI Agent Using Google Gemini and the SAGE Framework
«`html Understanding the Target Audience for Building a Self-Adaptive AI Agent The target audience for this coding implementation tutorial includes software developers, data scientists, and business professionals interested in AI applications. They seek to enhance their skills in building intelligent systems that can adapt and learn from their processes. Pain Points Lack of practical resources… →
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Ownership Mindset Drives Innovation: Milwaukee Tool CEO
Aleksandar Savic When Steve Richman became president of Milwaukee Tool in 2007, he joined an 83-year-old company selling a limited range of traditional power tools. “We were this small little company. … Our brand was your grandfather’s brand,” Richman recalled. “It was the brand of old plumbers and electricians and mechanical contractors.” With revenues under… →
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Acceptability and implementation potential of a health literacy intervention to increase colorectal cancer screening in deprived areas: A qualitative study of patients and general practitioners participating in a cluster randomized controlled trial
CONCLUSION: Our findings emphasize the need to tailor promotional materials for both patients and healthcare professionals to improve CCR screening uptake, balancing digital efficiency with maintaining core human relationships in healthcare. Such intervention can be integrated into different workflows. The addition of video into national CRC screening programs might also help. Targeting CRC screening interventions… →
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GTM 157: How ClickUp Scaled 17x and Cut CAC 3× — GTM Systems, Building Incrementally and Going from PLG to SLG | Gaurav Agarwal
The GTM Podcast is available on any major directory, including: Apple Podcasts Spotify YouTube Gaurav Agarwal is the COO of ClickUp, where he’s helped scale the company 17x in two years and cut CAC by 3x—all while leading across marketing, product, sales, and services. Formerly in banking and product roles, Gaurav brings a rare systems-oriented… →
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OpenAI Just Released the Hottest Open-Weight LLMs: gpt-oss-120B (Runs on a High-End Laptop) and gpt-oss-20B (Runs on a Phone)
OpenAI Just Released the Hottest Open-Weight LLMs: gpt-oss-120B (Runs on a High-End Laptop) and gpt-oss-20B (Runs on a Phone) Understanding the Target Audience The target audience for the new OpenAI models includes: Researchers seeking to explore AI capabilities and methodologies Developers looking for customizable solutions for application development Enterprise organizations aiming for secure, on-premises deployment… →