CONCLUSION: Dampening VAD vibration with a cotton buffer enhances comfort across sensitive sites, with reduced harshness and smoother sensation underlying preference. This simple modification may improve patient experience, encouraging broader VAD adoption. →

Background and Objectives: Children with mild intellectual disability (MID) frequently experience difficulties during dental treatment due to increased sensitivity to environmental stimuli and limited cooperation. Sensory-adapted dental environments (SADE) have been proposed as a strategy to improve the dental experience of patients with neurodevelopmental conditions; however, evidence regarding their effectiveness in children with MID remains… →

Background and Objectives: The Hypotension Prediction Index (HPI) is a predictive algorithm that enables proactive management of intraoperative hypotension (IOH) and has been integrated into finger cuff devices for practical use in obstetric settings. This study aims to evaluate the effectiveness of HPI in reducing IOH during elective cesarean sections (CS). Materials and Methods: This… →

Background: Subjective cognitive complaints (SCCs) are common in middle-aged and older adults and may reflect early cognitive changes, alongside alterations in stress, mood, sleep, and quality of life. N-PEP-12 is a peptide-based nutritional supplement with potential neuroprotective effects, but evidence of its benefits in healthy adults with SCCs remains limited. Objective: To evaluate the effects… →

Background: Lifestyle intervention is recommended as first-line management for individuals with low-to-moderate cardiovascular (CV) risk and elevated low-density lipoprotein cholesterol (LDL-C), although dietary intervention alone often produces only modest lipid reductions. NUT2 is a proprietary multi-component nutraceutical formulated to target complementary pathways involved in lipid metabolism, oxidative stress and cardiometabolic risk. This study evaluated its… →

CONCLUSIONS: A single neoadjuvant dose of atezolizumab was feasible, safe, and elicited measurable systemic immune activation in patients with resectable head and neck squamous cell carcinoma. Direct analysis of fresh blood uncovered dynamic PMN-MDSC changes as a potential novel pharmacodynamic biomarker of treatment response, emphasizing the advantages of real-time, non-frozen immune cell profiling for complete… →

CONCLUSIONS: Targeting the lateral margin of the fourth rib head for RFT achieved greater efficacy, better quality of life and higher patient satisfaction compared to the upper margin target. →

CONCLUSIONS: Recruitment source was associated with both participant characteristics and long-term retention in this digital HIV prevention intervention. Social media and prior research networks yielded higher retention, whereas partner-seeking apps reached populations at higher HIV risk but were associated with lower retention. Targeted retention strategies that account for both recruitment platform and participant characteristics (including… →

CONCLUSIONS: The LEARNS model-based self-management program benefits inpatients with newly diagnosed pulmonary tuberculosis. It effectively improves patients’ self-management and tuberculosis prevention and control knowledge, and improves chest radiographic findings. However, this intervention yields no significant effects on anxiety, depression, social support, and sputum bacteriological conversion. →