Clinical Trials
Category Added in a WPeMatico Campaign
-
Effect of myofascial release therapy applied to selective muscles on mobility and function in patients with temporomandibular dysfunction and co-occurring chronic low back pain: A randomized controlled trial
CONCLUSIONS: MFR therapy was effective in reducing symptoms of TMD and LBP-related disability and demonstrated greater benefit than exercise therapy in most outcome measures. The observed parallel improvements suggest a biomechanical and neuromuscular link between the jaw and lumbar region, supporting the integration of MFR in interdisciplinary rehabilitation for patients with comorbid TMD and LBP.
-
Enhancing clinical skills education through scenario-based simulation with debriefing: A randomized controlled study on bone marrow aspiration training
CONCLUSION: Debriefing-based simulation teaching improves teaching quality, clinical performance, learning motivation, and diagnostic thinking, and is broadly applicable in clinical skills education.
-
Evaluation of patients diagnosed with chronic obstructive pulmonary disease in terms of treatment compliance and quality of life after follow-up with telemedicine: a randomized controlled trial
CONCLUSIONS: Telemedicine has improved the quality of life of advanced-stage COPD patients and their inhaler techniques. It may, therefore, be considered a promising alternative to traditional face-to-face follow-ups, although various technical infrastructures and legal regulations are necessary.
-
Psychometric properties of the German Stroke and Aphasia Quality of Life Scale 39 generic version
CONCLUSIONS: The German SAQOL-39g is a reliable, valid and change-sensitive patient-reported outcome measure to assess the physical, communication and psychosocial quality of life in chronic post-stroke aphasia, with comparable psychometric properties and factorial structure to the original English version.
-
Sennosides vs magnesium hydroxide vs polyethylene glycol as a treatment for constipation in anorectal malformation: a randomized crossover trial
CONCLUSION: While PEG showed a trend towards better fecal clearance and Sennosides was preferred by users, no statistically significant differences in efficacy or user preference were found among the three laxatives.
-
Regulation of Somatosensory Temporal Discrimination Threshold Through Motor Training: An EEG and Kinematics Study
CONCLUSION: Actual execution (BRT) and motor imagery (VGI) enhance STDT through distinct neuroplastic mechanisms: BRT optimizes sensorimotor integration via parietal gamma/prefrontal theta oscillations, while VGI relies on ipsilateral parietal delta modulation. These findings underscore the role of cortical reorganization in motor learning and support tailored rehabilitation strategies for neurological disorders.
-
Effects of Traditional Chinese Medicine Rehabilitation Program on Knee Osteoarthritis in Aging Population: A Multicenter Randomized Controlled Trial
CONCLUSION: The TCM rehabilitation program improved knee function and reduced pain intensity in aging populations with knee osteoarthritis. Well-designed randomized controlled trials with long-term follow-up assessments are needed to draw more definitive conclusions. Trial registration Chinese Clinical Trial Register ChiCTR2000033351, date of registration: May 29, 2020.
-
Interpretability of Home Blood Pressure Measurements in Haemodialysis A Post Hoc Analysis of a Randomised Cross-Over Study
CONCLUSION: This study demonstrates the variability of BP measurement patterns if participants are not limited to measuring BP at a pre-specified frequency. Further studies are needed to assess optimal methods of standardising home BP monitoring in dialysis patients and to evaluate home BP thresholds that can be used as targets in randomised controlled trials.
-
Impact of a Novel Dietary Supplement on Efficacy of Pharmacological Treatments for Androgenic Alopecia: A Real-Life, Multicenter, Randomized, Assessor-Blinded Trial on 225 Subjects
CONCLUSION: Oral supplementation of AGA-P significantly increases the clinical efficacy of pharmacological treatments for mild-to-severe AGA/FAGA (Study Registration: ISRCTN-19671217).
-
Comparison of clinical effects of aspherical monofocal and Tecnis ZMB00 multifocal intraocular lenses in patients with age-related cataract
CONCLUSIONS: The multifocal intraocular lens outperformed the aspherical monofocal intraocular lens in improving the vision-related quality of life and rate of spectacle independence. However, it had dark vision defects and optical side-effects.