Clinical Trials
Category Added in a WPeMatico Campaign
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Investigation of varying frequencies of transcutaneous electrical nerve stimulation for labor pain control: a randomized double-blinded sham-controlled pilot study
CONCLUSION: Our findings suggest that a main study with a proper sample size based on this study investigating TENS1 may reveal if this set of frequencies reduces pain in laboring women.Clinical Relevance — This study suggests relevance of considering non-pharmacologic and neuromodulating approach in labor pain management.
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Efficiency and Diagnostic Utility of CO2 Cystoscopy After Laparoscopic Gynecologic Surgery
CONCLUSION: CO(2) cystoscopy is a safe, efficient, and diagnostically effective alternative to conventional saline cystoscopy following gynecologic laparoscopy. Its use significantly reduces procedural time without compromising the detection of urinary tract injuries and avoids the need for additional agents such as dyes or diuretics. These findings support the integration of CO(2) cystoscopy into routine intraoperative…
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Arthroscopic subacromial decompression versus placebo surgery for subacromial pain syndrome: 10 year follow-up of the FIMPACT randomised, placebo surgery controlled trial
CONCLUSION: In patients with subacromial pain syndrome, ASD offered no benefit over placebo surgery or exercise therapy during 10 year follow-up.
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Four-Year Effects of a Computer-Based Brief Alcohol Intervention Targeting Alcohol Users in the General Population: Randomized Controlled Trial
CONCLUSIONS: In a randomized controlled trial, no evidence for the efficacy of individualized feedback letters was found after 3 and 4 years. Unexpectedly, drinking reductions in the control group and no change in the intervention group were observed 4 years after the study start. Intervention strategies effective in at-risk drinkers may necessitate adaptation for applicability…
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Stereotype Threat and a Multiple Identity Intervention Among First- and Second-Generation Students of Migrant Descent
This study investigates the effects of stereotype threat on academic performance among first- and second-generation students of migrant descent in Austria and evaluates the effectiveness of a multiple identity intervention in mitigating such effects. In a randomized classroom quasi-experiment (N = 452, Mage = 15.15, 67.7% female), students were exposed to stereotype activation or control…
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Seven-Day vs Four-Day Infusion Set Replacement Interval and Catheter-Related Infections
CONCLUSIONS AND RELEVANCE: In this economic evaluation of the RSVP trial, a small increase in CRBSI risk was associated with large cost-savings and substantial health losses at the population level. While the RSVP trial assumed that a 2% equivalence margin was acceptable, the use of such arbitrary difference margins might not consider information that could…
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Clinical Evaluation of Thiamidol-Containing Formulations for the Visual Management of Facial Hyperpigmentation
CONCLUSION: These data support the use of Thiamidol-containing formulations as part of the overall management strategy for individuals affected by facial hyperpigmentation.  .
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Clindamycin Phosphate 1.2%/Adapalene 0.15%/ Benzoyl Peroxide 3.1% Gel for Moderate-to-Severe Acne: A Pooled Analysis by Age
CONCLUSIONS: Fixed-dose, triple-combination CAB gel was efficacious and well tolerated in participants with moderate-to-severe acne, regardless of age. Approximately half of the participants achieved clear/almost clear skin, with >70% reductions in lesion counts.
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Efficacy and safety of topical GT20029 in male patients with androgenetic alopecia: a multicenter, randomized, double-blind, placebo-controlled phase 2 study
CONCLUSION: Topical GT20029 demonstrated significant efficacy in hair regrowth with good tolerability. Further studies are warranted to confirm its therapeutic potential in AGA.
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Modulating the lung-gut axis: A randomized controlled trial of Xie Bai Zeng Ye decoction on intestinal flora and mucosal immunity in children with post-infectious cough
CONCLUSION: This exploratory study suggests that XBZY may be a promising treatment option for children with post-infectious cough characterized by lung heat and Yin deficiency. Compared with Montelukast Sodium, XBZY demonstrated superior short-term improvements in cough resolution, symptom relief, quality of life, intestinal barrier function, and gut microbiota modulation, while maintaining good safety. These findings…