Clinical Trials
Category Added in a WPeMatico Campaign
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The effect of supportive care on mood, general health, competence on caregivers of cancer patients, and supportive care needs on cancer patients undergoing chemotherapy: a controlled clinical trial
CONCLUSION: The results of this study revealed that the supportive care program was effective in mood states, general health, competence of caregivers, and grade of supportive care needs of cancer patients undergoing chemotherapy.
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Screening and Care for Emotional and Cognitive Problems After Ischemic Stroke: Results of a Multicenter, Cluster-Randomized Controlled Trial
BACKGROUND AND OBJECTIVES: Evidence regarding effectiveness of screening for emotional and cognitive problems after stroke is lacking. The primary aim of this study was to test the hypothesis that an intervention focusing on screening and care for emotional and cognitive problems after stroke would improve societal participation at 1 year. Second, we tested the hypotheses…
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Comparison of hypnosis plus sedoanalgesia and sedoanalgesia alone methods used in the ERCP procedure: A prospective randomized study
Endoscopic retrograde cholangiopancreatography (ERCP) is an interventional procedure that is often performed under sedation anesthesia and that is used in the diagnosis and treatment of hepatopancreaticobiliary diseases. The objective of this study was to compare the efficacy of hypnosis in conjunction with sedoanalgesia and sedoanalgesia alone in the context of outpatient anesthesia prior to ERCP.…
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Effects of the Laying on of Hands on Brain Electrical Activity in Epileptic Patients: A Randomized Controlled Clinical Trial
CONCLUSIONS: The findings suggest that the laying on of hands with healing intent as adjuvant therapy can promote changes at the neurophysiological level by increasing the alpha rhythm in patients with epilepsy. However, further studies with long-term follow-ups are warranted.
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Docosahexaenoic acid benefits on growth and body composition of septic neonates. Randomized trial
CONCLUSIONS: Enteral DHA administration reduced the retarded growth and undernourishment in neonates with late sepsis.
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Cognitive Behavioral Therapy for Insomnia With Prolonged Exposure Compared to Sleep Hygiene and Prolonged Exposure: A Randomized Controlled Trial
Objective: Co-occurrence of posttraumatic stress disorder (PTSD) and insomnia disorder is common and associated with greater psychiatric and functional problems than either condition alone. Evidence-based PTSD treatment often does not effectively decrease insomnia, and insomnia may interfere with the mechanisms underlying PTSD treatment. This study compared the efficacy of integrated cognitive behavioral therapy for insomnia…
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Comparative study between intralesional acyclovir versus intralesional 5-flurouracil in treatment of recalcitrant warts
CONCLUSION: Intralesional acyclovir and 5-FU are safe and effective methods in treatment of recalcitrant cutaneous warts.
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Optimizing muscle mass and function in advanced lung cancer patients: randomized, double-blind, placebo-controlled trial protocol using High Eicosapentaenoic acid and PROtein (HEPRO) to modulate epigenetics, reduce toxicity and improve gut microbiota
CONCLUSIONS: The HEPRO study aims to evaluate a viable dietary intervention strategy to improve MM and function in patients with lung cancer.
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Artificial intelligence-assisted diagnosis and prognostication in low ejection fraction using electrocardiograms in inpatient department: a pragmatic randomized controlled trial
CONCLUSIONS: Implementation of an AI-ECG algorithm enhanced the early diagnosis of low EF in the inpatient setting, primarily by improving diagnostic efficiency rather than increasing overall healthcare utilization. The tool was particularly effective in identifying high-risk patients who benefited from increased specialist consultation and more targeted diagnostic testing.
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Four months of treatment with anakinra combined with glucocorticoids for giant cell arteritis: a multicenter, randomized, double-blind, placebo-controlled trial
CONCLUSIONS: Although prematurely discontinued, this study does not support the use of 4 months of treatment with anakinra combined with GCs to reduce the risk of relapse or GC exposure.