Clinical Trials
Category Added in a WPeMatico Campaign
-
Impacts of Experimental Knee Pain on Gait Biomechanics and Pain Sensitivity: A Randomised Crossover Trial of Young and Pain-Free Volunteers
CONCLUSION: Changes in PPTs and propulsion impulse were observed after the knee pain induction. Peak knee pain variability can be partly explained using a combination of biomechanics, pain sensitivity and cognitive factors. This forms the basis for a targeted clinical evaluation of patients.
-
The effect of posture and breathing exercises applied with telerehabilitation on respiratory functions, exercise capacity, fatigue, and psychosocial factors in chronic obstructive pulmonary disease patients
CONCLUSION: It was concluded that exercise with telerehabilitation in COPD patients is effective on quality of life, exercise capacity, fatigue, psychosocial factors and can be used as a treatment approach.
-
Effect of flywheel resistance training on sleep quality in older women: A randomized controlled trial
CONCLUSION: Eight weeks of intervention did not affect objective sleep measures but improved subjective sleep quality, particularly in the FRT group.
-
Effectiveness of movement system impairment (MSI) based classification treatment on clinical outcomes among subjects with tibiofemoral hypomobility syndrome: A randomized controlled trial
CONCLUSION: The MSI treatment model effectively treats subjects with tibiofemoral hypomobility syndrome and shows greater improvement than standard physical therapy care. These findings suggest that MSI-based treatment can contribute to global health efforts to minimize musculoskeletal conditions. Further studies to bring long-term follow-up and other physical performance outcomes.
-
Evaluation of thiol-disulfide homeostasis under low and standard pneumoperitoneum in elderly patients undergoing laparoscopic cholecystectomy: a prospective comparative study
CONCLUSION: While higher intra-abdominal pressure may be associated with mild hepatic stress, it does not appear to cause significant oxidative imbalance in geriatric patients. Both low and high-pressure pneumoperitoneum levels can be used safely during laparoscopic cholecystectomy in elderly individuals, provided that appropriate perioperative management is ensured.
-
Effects of hydrotherapy kinetic chain exercises on muscle coactivation, pain management, and quality of life in men with chronic low back pain. Randomized clinical trial
CONCLUSION: The findings of this study underscore the importance of addressing the impaired coactivation of the transverse abdominal and multifidus muscles in men suffering from chronic non-specific low back pain. By implementing water kinetic chain exercises, we can effectively enhance muscle coactivation, which may lead to significant reductions in pain and improvements in overall quality…
-
Acute effects of an aerobic dual task on processing speed and attention in Parkinson’s disease: a randomised controlled trial study
CONCLUSIONS: The DT developed on the MOTOmed cycling device is a safe intervention for people diagnosed with PD (stage 2-3) with or without mild or moderate cognitive impairment. This intervention, associated with a cognitive intervention, seems to show improvements in the speed of information processing.
-
A composite endpoint for systemic sclerosis-associated interstitial lung disease: association with mortality in two clinical trial cohorts
CONCLUSION: The results of this post-hoc analysis provide further evidence that a composite endpoint comprised of physiological, radiological and patient-reported outcomes is a promising endpoint for SSc-ILD trials. Future validation studies are needed.
-
Earmuff and eye mask in the treatment of acute primary headache in emergency department: a randomized controlled open label study
CONCLUSIONS: Earmuffs combined with sleep eye masks as an adjunct to metoclopramide significantly enhance early headache relief in the emergency department and represent a safe, low-cost complementary therapy. Participants were not blinded to the intervention due to practical constraints, and for the same reason, placebo control was not used.
-
Novel syringe handle for one-handed anterior chamber paracentesis
CONCLUSIONS: We developed a novel syringe handle for one-handed AC paracentesis, which improved the safety and precision of the procedure while reducing procedural time. Its low-cost, reusable design and compatibility with standard syringes make it a practical tool for the procedure. Further clinical studies are warranted to explore broader applications.