Clinical Trials
Category Added in a WPeMatico Campaign
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Glycated Albumin Guided Therapy in Newly Diagnosed Type 2 Diabetes A Randomized Controlled Trial
CONCLUSION: GA-guided therapy did not enhance HbA1c < 7% achievement; however, its potential benefits for more stringent glycemic targets and metabolic parameters in early diabetes management deserve further investigation.
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A community-based protective behavioral strategies program for hazardous alcohol use among middle-aged men in rural Vietnam: A randomized controlled trial
CONCLUSION: The culturally adapted PBS-based group intervention reduced alcohol consumption and intention to drink among middle-aged rural Vietnamese men with HAU. Trials with attention-matched controls are needed.
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The effect of psychosocial skill-oriented group psychoeducation on functional recovery, treatment adherence, and mental well-being in patients diagnosed with schizophrenia: A randomized controlled trial
CONCLUSIONS: The findings indicate that psychosocial skills-focused group psychoeducation was associated with improvements in self-reported treatment compliance (although the low reliability of the adherence measure in this sample warrants cautious interpretation) in individuals diagnosed with schizophrenia and is an effective intervention for improving mental well-being and functional capacity. To increase the effectiveness of psychosocial skills-focused…
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The effect of psychodrama-based group work on postpartum women’s depression and forgiveness tendencies: A randomised controlled study
CONCLUSION: Psychodrama-based group work increased forgiveness tendencies and reduced depression levels among postpartum women. In this regard, it is recommended that psychodrama sessions be conducted with postpartum women.
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Reducing the diagnostic and treatment gap for priority mental, neurological and substance misuse disorders in primary care in rural Kenya: Results of a stepped wedge cluster randomized trial from the EPINA study
In resource-limited settings, improving care for mental, neurological and substance misuse (MNS) disorders is essential. This study evaluated the feasibility and effectiveness of implementing all adult modules of the WHO mental health Gap Action Programme Intervention Guide (mhGAP-IG) in primary healthcare (PHC) in rural Kenya through training non-specialist primary healthcare workers. We conducted a stepped-wedge…
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Detection of Cataract and Surgical Outcomes in the Manhattan Vision Screening and Follow-Up Study (NYC-SIGHT)
CONCLUSION: Cataract detection in underserved individuals was associated with older age, poor visual acuity, and unreadable fundus images but cataract surgery rates were low.
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Endobronchial Ultrasound-Guided Fine Needle Biopsy in the Diagnosis of Mediastinal Lymphadenopathy: A Randomized Trial
CONCLUSION: Despite similar diagnostic yields, FNB was more effective than FNA in providing larger, adequate core tissue samples. This improvement in specimen quality may suggest a potential clinical benefit for comprehensive diagnosis and advanced pathologic work-up.
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Educational intervention to improve adherence after acute coronary syndrome
CONCLUSION: The educational intervention was well accepted and feasible to implement, but it did not result in improved medication adherence or a reduction in clinical events over the medium term.
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VOLUMETRIC AND RADIOGRAPHIC OUTCOMES OF BONE REGENERATION AFTER APICOECTOMY WITH PRF-BASED THERAPIES — A PRELIMINARY STUDY
CONCLUSION: PRF enhances bone regeneration after apicoectomy, especially when combined with Bio-Oss, without increasing postoperative morbidity. CBCT volumetric assessment provides superior evaluation of regenerative outcomes.
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STANDARDIZED PATIENT-BASED TRAINING AND CLINICAL DIAGNOSTIC COMPETENCE AMONG MEDICAL STUDENTS: A RANDOMIZED COMPARATIVE STUDY
CONCLUSIONS: Standardized patient-based training was associated with improved clinical diagnostic performance, particularly among students with average or lower academic standing. These findings support the integration of standardized patients into hybrid clinical curricula to strengthen diagnostic competence and communication skills.