Clinical Trials
Category Added in a WPeMatico Campaign
-
A hybrid type 1 trial of a digital behaviour change intervention for frailty prevention in community-dwelling older adults aged 60 years and older
CONCLUSION: A DBCI promoting the adoption of AVOID behaviours among nonfrail, community-dwelling older people is effective in preventing frailty and improving QoL when implemented. Solving technical barriers and incorporating intelligent technologies could enhance impact.
-
A digital cognitive behavioural therapy programme for insomnia and anxiety in older adults: feasibility and preliminary efficacy
Insomnia and anxiety are highly prevalent and often comorbid in older adults. Although cognitive behavioural therapy is the first-line treatment for insomnia, few interventions simultaneously address both conditions. Furthermore, access remains limited by provider availability and high costs. To address these gaps, we developed an online CBT programme for insomnia and anxiety (eCBT+). This randomised…
-
Treatment of gingival recession type 1 using coronally advanced flap with leucocytes-platelet rich fibrin: a randomized controlled trial
CONCLUSION: Both CAF alone and CAF combined with L-PRF yielded comparable clinical and volumetric outcomes in RT1 treatments. No statistically significant advantages were observed with the adjunctive use of L-PRF.
-
The Feasibility and Acceptability of Culturally Appropriate Pulmonary Rehabilitation for Adults with Chronic Obstructive Pulmonary Disease in Sri Lanka: Randomized Controlled Trial
CONCLUSION: Culturally adapted PR was feasible and acceptable to adults with COPD in Sri Lanka. A fully powered trial is warranted for evaluating clinical and cost-effectiveness of culturally adapted PR.
-
Cost-Effectiveness of the START Hospital Addiction Consultation Service for Opioid Use Disorder Treatment
CONCLUSIONS AND RELEVANCE: In this trial-based economic evaluation, START was a cost-effective approach for addressing opioid use disorder in the inpatient setting by increasing the initiation of medication for OUD and linkage to OUD-focused care after discharge.
-
Effect of diode laser pretreatment on dentin thickness and discoloration in deep caries treated with biodentine: a randomized clinical trial
Preserving pulp vitality in deep carious lesions remains a clinical challenge. Indirect pulp capping with bioactive calcium silicate materials such as Biodentine has shown favorable biological outcomes, while diode laser irradiation has been proposed as an adjunct to enhance hemostasis, disinfection, and pulpal healing. However, evidence regarding their combined use is limited. This randomized controlled…
-
The Effects of Pilates-Based Tele-Exercise on Physical and Mental Health in Primary Dysmenorrhea
CONCLUSION: The findings demonstrate that Pilates-based tele-exercises significantly enhance the overall health and well-being of women with primary dysmenorrhea. This is achieved through improved menstrual symptoms and positive changes in attitudes toward menstruation. These results suggest that PBTE could be an effective non-pharmacological approach to managing primary dysmenorrhea.
-
Examination of the Effect of Emotional Freedom Technique on Quality of Life and Symptoms in Dysmenorrhea
CONCLUSION: It was determined that EFT reduces pain, alleviates symptoms, and enhances quality of life in women with dysmenorrhea symptoms.
-
Effect of Vimala infant massage on mothers with postpartum depression
CONCLUSIONS: Vimala IM is an effective intervention in reducing PPD symptoms, particularly self-blame. The absence of a partner increased the risk of developing PPD by up to 4 times.
-
Psychoeducation among women with breast cancer and emotional symptoms
CONCLUSION: The psychoeducational workshops demonstrated effectiveness to decrease the symptom burden for anxiety and depression. Early education and counselling for recently diagnosed BC patients should be considered part of the treatment to prevent and decrease these symptoms.