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Efficacy and safety of a topical nitric oxide-releasing solution (NORS) as a noninvasive treatment for plantar warts (verrucae plantaris)
CONCLUSION: NORS demonstrated favorable safety and early clinical activity, warranting larger, longer-term efficacy trials. →
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Five Trends in AI and Data Science for 2026
Carolyn Geason-Beissel/MIT SMR | Getty Images Organizations tend to change much more slowly than AI technology does these days. This means that forecasting enterprise adoption of AI is a bit easier than predicting technology change in this, our third year of making AI predictions. Neither of us is a computer or cognitive scientist, so we… →
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Clinical efficacy of 12 o’clock peripheral iridectomy in aphakic eyes undergoing pars plana vitrectomy with heavy silicone oil tamponade
Objective: To investigate the clinical effect of performing a 12 o’clock peripheral iridectomy during vitrectomy with heavy silicone oil tamponade in aphakic eyes. Methods: This was a prospective controlled study. Patients diagnosed with tractional retinal detachment secondary to proliferative diabetic retinopathy and scheduled to undergo combined lens extraction and pars plana vitrectomy with heavy silicone… →
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Cluster-randomized evaluation of neonatal intensive care unit quality improvement interventions in extremely preterm infants: secondary analysis of the INTACT trial
CONCLUSIONS: This secondary analysis of a cluster-randomized controlled trial demonstrated that the intervention group receiving a NICU-specific QI program had reduced acute-phase morbidities, particularly among infants born between 22 and 27 weeks of gestation. Our findings highlight the potential for widespread clinical implementation of QI programs based on participatory learning and action in neonatal intensive… →
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Smartphone-Based Real-Time Assessment of Daytime Insomnia Symptoms With Suvorexant: A Randomized Clinical Trial
CONCLUSIONS AND RELEVANCE: In this randomized clinical trial of older adults with insomnia, although traditional outcomes assessments detected no between-group differences, EMA was sensitive to detect effects of insomnia pharmacotherapy on daytime insomnia symptoms at various times of day, a critical gap in the literature. →
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Cost-Effectiveness of Home-Based Self-Sampling vs Clinician Sampling for Anal Precancer Screening
CONCLUSIONS AND RELEVANCE: The findings of this economic analysis suggest that home-based anal cancer screening is a cost-effective approach to increasing screening participation among SGM individuals. Home-based screening may serve as a valuable and efficient tool for expanding screening rates. →
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Stop Making Hollow Apologies at Work
Harry Haysom/Ikon Images Chad repeatedly undermined Sue by sharing private information behind her back to her subordinates. When Sue confronted him, Chad said he was sorry in order to move past the issue. Brenda continuously micromanaged her subordinates, leading to feelings of disrespect and low morale among her team members. When they talked to her… →
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Repeatability and quality assessment of QFR in the FAVOR III Europe trial: the REPEAT-QFR study
CONCLUSIONS: In FAVOR III Europe, agreement between in-procedure and core laboratory QFR was modest. Measurement variability increased with reduced angiographic quality, poor in-procedure QFR analysis quality, and more advanced coronary artery disease. →
