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The Three Obstacles Slowing Responsible AI
Anna & Elena Balbusso/theispot.com In October 2023, New York City released its AI action plan, publicly committing to the responsible and transparent use of artificial intelligence. The plan included guiding principles — accountability, fairness, transparency — and the creation of a new role to oversee their responsible implementation: the algorithm management and policy officer. But… →
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Personalization and Innovation in a Regulated Industry: Experian’s Kathleen Peters
Kathleen Peters brings a background with digital communications companies and tech startups to her role as Experian’s chief innovation officer. On this episode of the Me, Myself, and AI podcast, Kathleen shares a bit about Experian’s Innovation Lab, outlining some of its projects and explaining how the recent democratization of generative AI tools has made… →
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Effect of Valemetostat on the Pharmacokinetics of Midazolam and Digoxin: A Phase 1 Drug-Drug Interaction Study in Patients With Non-Hodgkin Lymphoma
Valemetostat tosylate (valemetostat) is an oral, potent, dual inhibitor of enhancer of zeste homolog (EZH)2/1, under investigation in non-Hodgkin lymphomas (NHLs) and solid tumors. In vitro, it inhibits cytochrome P450 3A (CYP3A) and P-glycoprotein (P-gp) when combined with sensitive CYP3A or P-gp substrates. This drug-drug interaction (DDI) sub-study is part of the phase 1 trial… →
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Computational Modelling Suggests Bacteriostatic Saline Does Not Reverse Botulinum Toxin-Induced Brow Ptosis
Anecdotal reports have recently circulated suggesting that intramuscular injection of bacteriostatic saline (BS)-which contains benzyl alcohol (BnOH)-can reverse botulinum toxin type A (BoNTA)-induced brow ptosis. Given the well-established intracellular persistence of BoNTA’s light chain and its irreversible cleavage of SNAP-25, such rapid functional recovery challenges existing pharmacological understanding. This study employed high-resolution pharmacokinetic/pharmacodynamic (PK/PD) modelling… →
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Cost-effectiveness of office-based, magnetic resonance imaging-guided transperineal versus transrectal prostate biopsy: An economic analysis of the PREVENT trial
CONCLUSIONS: In this model, TP biopsy was more cost-effective than TR from a health care payer perspective. In the setting of increasing concerns about the risk of infection from traditional TR biopsy, these findings suggest that office-based TP biopsy is a more cost-effective population-level alternative. →
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How Exploration Agents like Q-Learning, UCB, and MCTS Collaboratively Learn Intelligent Problem-Solving Strategies in Dynamic Grid Environments
«`html How Exploration Agents like Q-Learning, UCB, and MCTS Collaboratively Learn Intelligent Problem-Solving Strategies in Dynamic Grid Environments Understanding the Target Audience The target audience for this tutorial includes data scientists, machine learning engineers, and business analysts interested in applying reinforcement learning techniques to solve complex problems. These individuals typically work in technology-driven industries and… →
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GTM 168: How ZoomInfo Built a $1B RevOps Engine, The Operating Cadence Behind Breakout Growth | Tessa Whittaker
The GTM Podcast is available on any major directory, including: Apple Podcasts Spotify YouTube Tessa Whittaker is the VP of Revenue Operations at ZoomInfo, where she leads a 70-person global team powering one of SaaS’s most efficient $1B+ revenue engines. Over the past decade, she’s helped architect the systems, cadence, and AI workflows that underpin… →
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MiniMax Open-Sources MiniMax M2: A Mini Model Built for Max Coding and Agentic Workflows at 8% Claude Sonnet Price and ~2x Faster
MiniMax Open-Sources MiniMax M2: A Mini Model Built for Max Coding and Agentic Workflows Understanding the Target Audience The target audience for MiniMax Open-Sources MiniMax M2 includes software developers, data scientists, and AI researchers who are engaged in coding and agentic workflows. These professionals often face challenges such as: High costs associated with flagship AI… →
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Cardiac Effects of Dapagliflozin in People with Chronic Kidney Disease
CONCLUSIONS: In a heterogeneous population of patients with chronic kidney disease, dapagliflozin significantly reduced left ventricular mass index compared with placebo. These findings provide mechanistic insights into the early treatment benefits of SGLT2 inhibitors seen previously in chronic kidney disease. Further research is needed to replicate and further define these early treatment benefits. (Funded by… →
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Cost-Effectiveness of Single Versus Multiple Sessions of Physical Therapy for Adults With Spinal Disorders: An Economic Evaluation From a Pragmatic Randomized Controlled Trial
OBJECTIVE: To evaluate the cost-utility of a single session compared with multiple sessions of physical therapy care for adults with spinal disorders. DESIGN: Economic evaluation based on a pragmatic randomized controlled trial. METHODS: Patients with spinal disorders who were referred for a spinal surgery consultation and triaged as nonsurgical cases by an advanced practice physical… →
