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Impact of treatment interruption on the efficacy and safety of vunakizumab in patients with moderate-to-severe plaque psoriasis: a post-hoc analysis of a phase 3 trial
CONCLUSION: Interrupted vunakizumab treatment reduced the clinical response and quality of life in patients with moderate-to-severe plaque psoriasis. →
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Efficacy of Intralesional Triamcinolone Acetonide Combined With Cryotherapy Compared to Intralesional Triamcinolone Acetonide Alone in Treating Limited Patchy Alopecia Areata of the Scalp and Face: A Prospective, Randomized, Within-Subject Controlled Trial
CONCLUSION: This study demonstrated that both combination therapy and triamcinolone injection are equally effective in treating alopecia. However, future research with a larger sample size, extended follow-up, and comparisons of trichoscopic findings is warranted. →
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The Vicious Cycle of Long Wait Times
There’s only so long that you can keep a customer waiting. Whether it’s for a food order or a doctor’s appointment, “as customers wait in a queue, there comes a point when they eventually get so bored or frustrated that they leave,” says Achal Bassamboo, a Kellogg professor of operations. This problem of customers leaving… →
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Is AI Turning Back the Clock on the Job Market?
For more than a century, the effect of technology on jobs followed a clear trend: as machines took over manual tasks, blue-collar professions suffered, while white-collar occupations enjoyed gains. But AI seems poised to follow the opposite trend. The ability of AI to handle office tasks, such as copywriting and data analysis, seems more likely… →
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In Price Negotiations, Every Second Counts
Bargaining is a fundamental part of doing business, whether it’s for an everyday interaction like buying used furniture on Facebook Marketplace or a high-stakes negotiation involving wages or trade agreements. “Bargaining is everywhere,” says Caio Waisman, an economist and an associate professor of marketing at the Kellogg School. It’s been a focal point for businesses… →
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4 Trends to Watch in China’s Economy
As 2026 dawns, headwinds are multiplying for many of the world’s economies, and even China hasn’t been able to shake off the uncertainty. The world’s second-largest economy has been one of the great success stories of the last 50 years, growing at the astonishing pace of 10 percent per year and becoming a dominant player… →
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Protective effect of pituitrin combined with norepinephrine on cardiopulmonary injury in patients with septic shock diagnosed by critical care ultrasound evaluation
CONCLUSION: ADH combined with NE can effectively improve the inflammatory response, cardiac and pulmonary function indexes of septic patients, and exert significant cardiopulmonary protection effects. It is a viable and effective therapeutic strategy for septic patients. →
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Could Primary Contact Physical Therapy Improve Emergency Department Care While Being Efficient? A 3-Month Cost-Utility Analysis
OBJECTIVE: To evaluate the cost utility of 2 emergency department (ED) care models: management by an emergency physician (EP; usual care), and management by a primary contact physical therapist (PT) and an EP (PT + EP; intervention). DESIGN: Cost-utility analysis based on data collected during a pilot pragmatic randomized clinical trial over a 3-month period… →
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Treatment of Youth Misophonia: A Randomized Controlled Trial Comparing Transdiagnostic Cognitive-Behavioral Therapy to Psychoeducation and Relaxation Training
Misophonia is a distinct clinical disorder that lacks official diagnostic classification. Despite growing evidence of the prevalence and impairment associated with this condition, little research has tested possible evidence-based interventions. The current study presents outcomes from a two-site randomized controlled trial (N = 43) comparing the efficacy of the Unified Protocols for Transdiagnostic Treatment of… →
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Interval cancer, sensitivity, and specificity comparing AI-supported mammography screening with standard double reading without AI in the MASAI study: a randomised, controlled, non-inferiority, single-blinded, population-based, screening-accuracy trial
BACKGROUND: Evidence indicates that artificial intelligence (AI) can improve mammography screening by increasing cancer detection and reducing screen reading workload, but its effect on interval cancers (primary breast cancers diagnosed between two screening rounds or within 2 years after the last scheduled screening that were not detected at screening) is unknown. We aimed to compare… →
