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Effect of race and sex on lupus diagnosis in primary care: A randomized factorial survey study
CONCLUSION: A patient’s race and sex may influence diagnostic accuracy and clinical decision-making for SLE in primary care. The observed variation in diagnostic accuracy, which aligns with the descriptive epidemiology of SLE, highlights the need for targeted interventions to ensure equitable diagnostic processes. →
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Randomized controlled trial on the effects of different antibiotic regimens in preterm premature rupture of membranes after 34 weeks
CONCLUSION: The 2 different antibiotic regimens administered to pregnant women diagnosed with PPROM after the 34th week of gestation demonstrated similar clinical effects in terms of maternal and neonatal outcomes. Although the differences in NICU stay duration and the number of chorioamnionitis cases were not statistically significant, we believe that these findings could reach significance… →
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How to Price Your AI Product: A Practical Guide for Early-Stage Founders
Pricing is one of the hardest decisions founders make. And in the AI era, it’s become one of the most critical to get right. Costs move quickly, usage patterns shift unpredictably, and buyers are suddenly much more sensitive to how value gets delivered. What used to be a simple question of “What should we charge?”… →
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Feasibility of an Indigenous Food Is Medicine Program for Patients With Heart Failure in Rural Navajo Nation: The MUTTON-HF Nonrandomized Clinical Trial
CONCLUSIONS AND RELEVANCE: In this nonrandomized clinical trial, the MUTTON-HF intervention incorporating Indigenous recipes and locally sourced Native food was feasible and acceptable for patients with heart failure in rural Navajo Nation. These findings will inform a future randomized clinical trial to evaluate the effectiveness of this intervention to advance Indigenous cardiovascular health and food… →
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Remimazolam vs. midazolam sedation in upper gastrointestinal endoscopy in adults 65 years: Randomized controlled trial
CONCLUSIONS: In performing upper gastrointestinal endoscopy in older patients, remimazolam can be a good alternative sedative to midazolam, whether used as monotherapy or in combination therapy. →
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Effectiveness of flipped classroom on module of severe acute malnutrition among undergraduate students: A randomized controlled study
Background Flipped classroom (FC) teaching is a distinctive method in which a reversal occurs between lecture and homework components. This model differs entirely from traditional classroom teaching and data regarding its effectiveness are sparse. Our primary objective was to evaluate the improvement in post-session test scores and self-acquired confidence between the FC and traditional lecture-based… →
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Enshittification Comes to ‘Smart’ Products
Brian Stauffer/theispot.com When technology journalist Cory Doctorow coined a new term to describe how the consumer experience on platforms such as Amazon, Facebook, and Google has degraded over time, his observations resonated so widely that the American Dialect Society named enshittification its word of the year in 2023. Doctorow argued that platform operators follow a… →
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3 Signs It’s Time for Your Next Chapter
If you’ve ever been to a party, you know that awkward dilemma: When should you leave? Bail out too early and you may miss out on fun and meaningful connections. Stick around and you may end up overstaying your welcome—often without realizing it. Knowing the right time to head for the exit at a job… →
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Pharmacokinetic Modeling of Ticagrelor and Ticagrelor Active Metabolite Removal by the DrugSorb-ATR Device in a Randomized Controlled Study of Patients Undergoing Cardiac Surgery
Excessive surgical bleeding is a potential risk in patients taking ticagrelor who must undergo urgent cardiothoracic (CT) surgery before adequate washout of the drug can occur. The DrugSorb-Antithrombotic removal (ATR) device is a polymer sorbent-filled hemoadsorption cartridge that can remove unbound (active) fractions of ticagrelor and ticagrelor active metabolite (TAM) from blood. STAR-T was a… →
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The effects of a mobile application-based dementia care intelligent recommender system on caregivers of people with dementia: a randomized controlled trial
CONCLUSION: In summary, this RCT showed that the DCIRS may reduce caregivers’ distress related to care problems and lessen caregiver burden. Although depressive symptoms did not improve significantly, further research is needed to assess long-term effects and clarify the mechanisms underlying remote, personalized interventions such as the DCIRS. →
