CONCLUSIONS: Ivermectin and colchicine have no beneficial effect over standard care in the treatment of COVID-19. →
BACKGROUND: The Scottish Computed Tomography of the Heart (SCOT-HEART) trial demonstrated that management guided by coronary CT angiography (CCTA) improved the diagnosis, management, and outcome of patients with stable chest pain. We aimed to assess whether CCTA-guided care results in sustained long-term improvements in management and outcomes. →
CONCLUSIONS: Multiple sessions of HD-tDCS over the medial prefrontal cortex appears to have potential to produce meaningful cognitive enhancements in a proportion of patients having AD with improvements maintained for at least 8 weeks in some. →
BACKGROUND: No treatments exist for apathy in people with frontotemporal dementia. Previously, in a randomised double-blind, placebo-controlled, dose-finding study, intranasal oxytocin administration in people with frontotemporal dementia improved apathy ratings on the Neuropsychiatric Inventory over 1 week and, in a randomised, double-blind, placebo-controlled, crossover study, a single dose of 72 IU oxytocin increased blood-oxygen-level-dependent signal… →
Advancements in multimodal intelligence depend on processing and understanding images and videos. Images can reveal static scenes by providing information regarding details such as objects, text, and spatial relationships. However, this comes at the cost of being extremely challenging. Video comprehension involves tracking changes over time, among other operations, while ensuring consistency across frames, requiring… →
The artificial intelligence (AI) landscape is evolving rapidly, but this growth is accompanied by significant challenges. High costs of developing and deploying large-scale AI models and the difficulty of achieving reliable reasoning capabilities are central issues. Models like OpenAI’s GPT-4 and Anthropic’s Claude have pushed the boundaries of AI, but their resource-intensive architectures often make… →
AI has entered an era of the rise of competitive and groundbreaking large language models and multimodal models. The development has two sides, one with open source and the other being propriety models. DeepSeek-R1, an open-source AI model developed by DeepSeek-AI, a Chinese research company, exemplifies this trend. Its emergence has challenged the dominance of… →
As large language models (LLMs) continue to evolve, understanding their ability to reflect on and articulate their learned behaviors has become an important aspect of research. Such capabilities, if harnessed, can contribute to more transparent and safer AI systems, enabling users to understand the models’ decision-making processes and potential vulnerabilities. One of the biggest challenges… →
Aims/Background Overactive bladder (OAB) is a prevalent chronic condition affecting approximately 12% of adults, with incidence increasing with age. While pharmacological and behavioural therapies are standard treatments, their efficacy is often limited by side effects and poor adherence. This study aimed to compare the therapeutic effects of precision magnetic stimulation guided by motor-evoked potential with… →
Bacterial prostatitis (BP) is a common prostatic infection characterized by pain and urinary symptoms, often with negative bacterial cultures from prostatic secretions. It affects young and older men bimodally and impacts quality of life (QoL) significantly. Background and Objectives: Treatment typically involves antibiotics, but a multimodal approach with additional nutraceuticals may enhance outcomes. This study… →