CONCLUSION: ADOPT model-based nursing intervention significantly improved self-management ability and quality of life while reducing postoperative complications in patients with middle and low rectal cancer after sphincter-preserving surgery. This structured approach provides evidence for incorporating ADOPT into clinical practice to optimize postoperative care. →

CONCLUSION: Intervention with this probiotic formula was associated with a shorter duration of fever and pain/discomfort in pediatric URIs with pharyngitis. →

Mycotoxin contamination is a global threat to food safety and human health, especially in regions facing food insecurity, such as Sub-Saharan Africa. This intervention study evaluates the effectiveness of nixtamalization, a traditional alkaline cooking method, in reducing mycotoxin levels in maize and corresponding urinary biomarkers of exposure. Forty adult healthy volunteers from an informal settlement… →

Chronic pain significantly impairs functional performance in patients with cancer. Although acupuncture is effective for cancer-related pain, its impact on pain-related functional interference remains unclear. This secondary analysis of the PEACE randomized clinical trial included patients with prior cancer diagnoses and musculoskeletal pain for ≥3 months. Participants were randomized to groups undergoing 10 weeks of… →

CONCLUSION: These results indicate that digital co-creation enhances the active participation of older adults in Tele-PR and fosters the development of virtual communities along with the onset of altruistic behaviors in individuals. This approach encourages patients to apply their knowledge for self-management of health behaviors, which in turn, enhances their adherence to rehabilitation exercise and… →

CONCLUSIONS: The combination of SBRT, cadonilimab, and lenvatinib showed promising efficacy and manageable toxicity in HCC patients with Vp3/4 PVTT. Early AFP or PIVKA-II response at 6 weeks may serve as a prognostic biomarker. →

CONCLUSION: Anticipatory nursing care enhances treatment adherence and improves the quality of life in PE patients. →

CONCLUSIONS: In this controlled trial, metformin did not significantly improve the primary outcome of ABC total score. However, significant improvements were observed in the hyperactivity subscale and key secondary outcomes, including sleep parameters, while maintaining a favorable safety profile. Although the primary endpoint was not met, these secondary findings support further investigation of metformin for… →