OBJECTIVE: Combined biopsy (CBx) is a combination of multiparametric magnetic resonance imaging (MpMRI)-targeted prostate biopsy (FBx) and systematic biopsy (SBx). CBx offers highly accurate diagnostic rates, but the increased number of cores taken and the longer procedure time may pose challenges in tolerability compared to traditional biopsies in terms of pain and anxiety. This situation… →
Multimodal Large Language Models (MLLMs) have gained significant attention for their ability to handle complex tasks involving vision, language, and audio integration. However, they lack the comprehensive alignment beyond basic Supervised Fine-tuning (SFT). Current state-of-the-art models often bypass rigorous alignment stages, leaving crucial aspects like truthfulness, safety, and human preference alignment inadequately addressed. Existing approaches… →
Humans possess an innate understanding of physics, expecting objects to behave predictably without abrupt changes in position, shape, or color. This fundamental cognition is observed in infants, primates, birds, and marine mammals, supporting the core knowledge hypothesis, which suggests humans have evolutionarily developed systems for reasoning about objects, space, and agents. While AI surpasses humans… →
CONCLUSION: 30% SSA reduced papules and pustules in rosacea, improved persistent erythema, and enhanced stratum corneum hydration in the 30% SSA-treated group compared to the placebo group. No significant differences were observed in TEWL and skin pH values between the two groups. Our findings suggest that 30% SSA is an effective and safe option for… →
INTRODUCTION: Postoperative delirium (POD) is a common postoperative complication and is associated with numerous adverse outcomes. Advanced age and hip surgery are high risk factors for POD. Both remimazolam tosilate for injection and sevoflurane can be used as sedatives for the maintenance of general anesthesia, but the comparison of their impacts on the incidence of… →
On February 17, 2025, xAI introduced Grok 3, an advanced AI model built to rival industry leaders with cutting-edge technology, real-time data processing, and a hybrid architecture. Elon Musk has described Grok 3 as the “smartest AI on Earth,” emphasizing its superior reasoning capabilities, tenfold increase in computing power over its predecessor and a design… →
CONCLUSION: Gadobenate was superior to gadoxetate for the differentiation and diagnosis of malignant and benign FLLs for two of three readers. Further confirmatory studies that include a wider representation of different types of FLLs are warranted. →
In the realm of artificial intelligence, enabling Large Language Models (LLMs) to navigate and interact with graphical user interfaces (GUIs) has been a notable challenge. While LLMs are adept at processing textual data, they often encounter difficulties when interpreting visual elements like icons, buttons, and menus. This limitation restricts their effectiveness in tasks that require… →
Efficiently handling long contexts has been a longstanding challenge in natural language processing. As large language models expand their capacity to read, comprehend, and generate text, the attention mechanism—central to how they process input—can become a bottleneck. In a typical Transformer architecture, this mechanism compares every token to every other token, resulting in computational costs… →
Whole Slide Image (WSI) classification in digital pathology presents several critical challenges due to the immense size and hierarchical nature of WSIs. WSIs contain billions of pixels and hence direct observation is computationally infeasible. Current strategies based on multiple instance learning (MIL) are effective in performance but considerably dependent on large amounts of bag-level annotated… →