CONCLUSIONS AND RELEVANCE: In this randomized clinical trial of TPS in patients with AD, a 2-week verum treatment improved cognitive scores in the younger subgroup, ameliorated depressive symptoms, and induced upregulation of functional brain activation and connectivity. These findings suggest TPS may be a safe and promising add-on therapy for patients with AD receiving state-of-the-art… →
CONCLUSIONS AND RELEVANCE: In this study, the delivery of a care bundle was not associated with higher child well-being 30 days after an ED visit. Hospitalizations did decrease during bundle delivery, but ED LOS did not. These health system findings may have been affected by broader changes in patient volumes and flow processes that occurred… →
Objective: To examine the effects of treatment sequence of parent stimulant medication (MED) and behavioral parent training (BPT) on child, maternal, and parenting outcomes among multiplex attention-deficit/hyperactivity disorder (ADHD) families using a pilot Sequential Multiple Assignment Randomized Trial (SMART) design. →
Access to high-quality textual data is crucial for advancing language models in the digital age. Modern AI systems rely on vast datasets of token trillions to improve their accuracy and efficiency. While much of this data is from the internet, a significant portion exists in formats such as PDFs, which pose unique challenges for content… →
Comparing language models effectively requires a systematic approach that combines standardized benchmarks with use-case specific testing. This guide walks you through the process of evaluating LLMs to make informed decisions for your projects. Table of contents Step 1: Define Your Comparison Goals Step 2: Choose Appropriate Benchmarks General Language Understanding Reasoning & Problem-Solving Coding &… →
LLMs have exhibited impressive capabilities through extensive pretraining and alignment techniques. However, while they excel in short-context tasks, their performance in long-context scenarios often falls short due to inadequate long-context alignment. This challenge arises from lacking high-quality, long-context annotated data, as human annotation becomes impractical and unreliable for extended contexts. Additionally, generating synthetic long-context data… →
Background and Objectives: Chronic pelvic pain (CPP) is a common complication of pelvic inflammatory disease (PID). Although acupuncture has been increasingly used for the management of CPP, there is insufficient research to support the use of laser stimulation of sensitized acupoints. This study aimed to investigate the effects of laser on sensitized acupoints on pelvic… →
Background and Objectives: Fibromyalgia (FM), through the presence of widespread chronic pain, stiffens the musculoskeletal system and causes sleep disturbances and fatigue. Through this study, we aimed to compare the effectiveness of two different recovery interventions for improving sleep quality: a standard, multidisciplinary intervention in a recovery hospital versus a therapy focused on intrinsic relaxation… →
Background and Objectives: Prediabetes is a medical disease characterized by elevated blood sugar levels that exceed normal levels but do not meet the criteria for a diagnosis of diabetes mellitus. This study aimed to assess the impact of structured exercise manual interventions on the biochemical markers of sedentary prediabetic patients over sixteen weeks. Materials and… →
Background/Objectives:Clostridioides difficile infection (CDI) is an important nosocomial diarrheal disease. The benefits of the probiotic Bacillus licheniformis (B. licheniformis) in the preservation of intestinal microbiota have not been studied in patients with CDI to date. Therefore, we aimed to investigate the efficacy of B. licheniformis in preserving the intestinal microbiota in patients with CDI. Methods:… →