CONCLUSION: This trial will evaluate the efficacy of a harmonica-integrated, home-based PR program with tele-supervision for COPD patients on lung function, respiratory muscle strength, exercise capacity, and overall health. If effective, it could offer a novel, affordable, and accessible home-based PR approach for COPD management. →
There is limited understanding of how well patients adhere to postoperative instructions following ankle surgery, particularly in outpatient settings regarding partial weight bearing (15-30 kg) and orthosis use. This study aims to assess orthosis compliance and load frequency over six weeks post-surgery using pressure-sensitive insoles, while also evaluating the effectiveness of continuous biofeedback. A total… →
Background/Objectives: Chronic low-grade inflammation is associated with insulin resistance and poor glycemic control, leading to the development of type 2 diabetes mellitus (T2DM). The present study investigated the effect of regular mango intake on inflammation and insulin sensitivity in participants with overweight or obesity and chronic low-grade inflammation. Methods: A human clinical study was performed… →
CONCLUSIONS: Probiotic supplementation may serve as an alternative supporting treatment, especially in the phenotype of women with a high FAI index. Probiotic therapy is also effective in reducing BMI in overweight women with PCOS. →
CONCLUSIONS: A novel educational intervention about ICI risks and benefits was feasible to deliver, deemed acceptable, and shows promise in improving knowledge and activation to ask questions without increasing anxiety. A future study evaluating UPLIFT’s efficacy in these and other outcomes, including severe ICI toxicity, is warranted. →
Artificial intelligence models face a fundamental challenge in efficiently scaling their reasoning capabilities at test time. While increasing model size often leads to performance gains, it also demands significant computational resources and extensive training data, making such approaches impractical for many applications. Traditional techniques, such as expanding model parameters or employing Chain-of-Thought (CoT) reasoning, rely… →
Artificial intelligence has made significant strides, yet developing models capable of nuanced reasoning remains a challenge. Many existing models struggle with complex problem-solving tasks, particularly in mathematics, coding, and scientific reasoning. These difficulties often arise due to limitations in data quality, model architecture, and the scalability of training processes. The need for open-data reasoning models… →