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Clinicians’ perspectives on a primary healthcare intervention to reduce antibiotic prescription for acute lower respiratory tract infections in Barcelona (Spain): a qualitative study
CONCLUSIONS: CPR testing and promoting communication skills can be useful tools to support clinical decisions for ALRTIs. Structural barriers (e.g., healthcare pressures) and social inequities amongst service users were acknowledged as the main barriers for the implementation of ALRTIs interventions. →
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Evaluating a brief imagery-based intervention for adolescent depression: study protocol for a Phase IIB randomised control trial (INDIGO) in secondary schools
BACKGROUND: There is an urgent need for psychological interventions that can target depression in late adolescence and prevent it from having lifelong implications. Schools have been identified as a promising setting to enhance access to interventions and offer support earlier. We have co-developed a novel intervention, IMAGINE, that targets key cognitive mechanisms implicated in depression… →
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Graded motor imagery as an adjunct to comprehensive physiotherapy in chronic rotator cuff-related pain: a single blind randomized controlled trial
CONCLUSION: This study highlights that both groups showed significant improvements in pain, range of motion, functionality, and pain-related fear. However, adding GMI therapy led to faster pain relief, better mechanical sensitivity, improved motor imagery skills, and greater treatment satisfaction, warranting further research with larger samples and extended follow-ups to confirm its broader applicability. →
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Consumer-Focused Osteoarthritis e-Learning to Complement Physiotherapy Care in People With Knee Osteoarthritis: Protocol for the PEEKO Randomised Controlled Trial
CONCLUSION: This RCT evaluates whether supplementing physiotherapy care with consumer-focused e-learning improves outcomes for people with knee OA. →
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The Six Most Popular Stories of 2025 — So Far
Sometimes a concept captivates our readers. With the publication of “Philosophy Eats AI” in January, Michael Schrage and David Kiron didn’t just put an intellectual stake in the ground: They started a business leadership discussion. Consider their assertion: Philosophy is eating AI: As a discipline, data set, and sensibility, philosophy increasingly determines how digital technologies… →
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A Tutorial on Using OpenAI Codex with GitHub Repositories for Seamless AI-Powered Development
«`html A Tutorial on Using OpenAI Codex with GitHub Repositories for Seamless AI-Powered Development Understanding the Target Audience The target audience for this tutorial includes software developers, engineers, and project managers who are looking to enhance their coding processes through AI. They are typically familiar with GitHub and coding practices but may feel overwhelmed by… →
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Crome: Google DeepMind’s Causal Framework for Robust Reward Modeling in LLM Alignment
«`html Crome: Google DeepMind’s Causal Framework for Robust Reward Modeling in LLM Alignment Understanding the Target Audience The target audience for Crome includes AI researchers, data scientists, business leaders, and technology innovators focused on enhancing language model performance and alignment. Their pain points include challenges with reward hacking in machine learning, limitations in existing reward… →
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Thought Anchors: A Machine Learning Framework for Identifying and Measuring Key Reasoning Steps in Large Language Models with Precision
«`html Thought Anchors: A Machine Learning Framework for Identifying and Measuring Key Reasoning Steps in Large Language Models with Precision Understanding the Target Audience The target audience for the Thought Anchors framework primarily includes AI researchers, data scientists, business analysts, and decision-makers in industries such as healthcare and finance. These professionals are often tasked with… →
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Early Neurodevelopment of Extremely Preterm Infants Administered Autologous Cord Blood Cell Therapy: Secondary Analysis of a Nonrandomized Clinical Trial
CONCLUSIONS AND RELEVANCE: This phase 1 nonrandomized clinical trial assessing the safety and feasibility of autologous UCBCs in extremely preterm infants did not find significant differences in brain imaging parameters and early neurodevelopmental outcomes between the cell therapy and contemporaneous untreated groups. It was encouraging to note no infants who received UCBCs were assessed as… →
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Balancing Efficiency and Accuracy in Hepatitis C Rapid Antibody Testing: Insights From a Cluster Randomised Crossover Trial
Hepatitis C remains a significant global health problem, particularly among people who inject drugs. To achieve Australia’s 2030 elimination targets, efficient testing strategies are needed. The OraQuick rapid antibody test provides results in 20 min, but many non-viraemic individuals with resolved infections test positive, potentially leading to unnecessary confirmatory RNA testing. Reducing the read time… →
