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  • The effects of povidone-ıodine and chlorhexidine gluconate on the ocular surface after phacoemulsification cataract surgery

    15 ноября, 2025

    CONCLUSION: Both PI and CHG caused transient ocular surface changes after cataract surgery. However, CHG demonstrated faster recovery of tear film parameters and improved early postoperative comfort, suggesting it may be a preferable antiseptic in patients with ocular surface sensitivity. →

    Clinical Trials
  • Clinical and cost-effectiveness of a standardised diagnostic assessment for children and adolescents with emotional difficulties: the STADIA multi-centre RCT

    15 ноября, 2025

    CONCLUSIONS: We found no evidence that completion of the development and well-being assessment aided the detection of emotional disorders in this study. Using the development and well-being assessment in this way cannot be recommended for clinical practice. →

    Clinical Trials
  • Application and Efficacy Evaluation of a Modified Ostomy Appliance in Managing Peristomal Irritant Contact Dermatitis: A Randomised Controlled Trial

    15 ноября, 2025

    Irritant contact dermatitis is a common peristomal skin complication. Due to the continuous irritation from intestinal fluids and faeces, the healing of this dermatitis is slow and the condition severely impairs patients’ quality of life. The study aimed to evaluate the efficacy of a modified insertable ostomy appliance in promoting healing and improving patient outcomes.… →

    Clinical Trials
  • Procedural characteristics and clinical outcomes from same-day discharge after pulsed field ablation treatment for atrial fibrillation: an admIRE trial sub-analysis

    15 ноября, 2025

    CONCLUSION: SDD is feasible in a paroxysmal AF population undergoing PFA with the VLCC, demonstrating comparable safety and effectiveness outcomes with overnight hospitalization. →

    Clinical Trials
  • Perceived health, musculoskeletal disorders, work conditions and safety climate in relation to patient handling and movement - a multicentre cross-sectional study at healthcare workplaces

    15 ноября, 2025

    CONCLUSIONS: Substantial physical and organizational challenges related to PHM were reported by HCWs across both care contexts. The findings suggest that interventions emphasizing leadership engagement, a systematic approach to training, and tailored solutions are essential to strengthen the safety climate and reduce HCWs’ health risks. →

    Clinical Trials
  • Group-Based Relational Savoring Intervention in Mothers of Young Children in Iran: Testing Impacts of Memory Type

    15 ноября, 2025

    Relational savoring, a prevention/intervention approach that involves reflecting on positive moments of connection with another person, promotes wellbeing in the parenting relationship. In this program, parents savor memories with strong attachment content (including Secure Base or Safe Haven memories), but it is currently unknown whether the benefits of relational savoring differ as a function of… →

    Clinical Trials
  • Ten-year target lesion failure in patients treated with primary PCI: results from DANAMI-3

    15 ноября, 2025

    CONCLUSIONS: One in five STEMI patients treated with primary PCI experiences TLF within 10 years, accounting for a significant proportion of any mortality, any MI or any revascularisation, with sustained occurrence rates beyond the first year. →

    Clinical Trials
  • Cost-effectiveness of a technology-assisted peer-delivered perinatal mental health intervention in Pakistan: an economic evaluation using trial evidence

    15 ноября, 2025

    CONCLUSIONS: Our analysis suggests that THP-TAP could represent a scalable, health-improving and cost-saving intervention to support those with perinatal depression, when compared with WHO-THP. →

    Clinical Trials
  • Perceived effectiveness of messages to address cervical cancer screening barriers: An online experiment

    15 ноября, 2025

    CONCLUSIONS: Messages targeting known barriers to cervical cancer screening were perceived as more effective than a control message. These messages could increase cervical cancer screening rates if used in interventions at scale. →

    Clinical Trials
  • Transepidermal Water Loss in Oral Food Challenges in Children With Peanut Allergy: A Randomized Clinical Trial

    14 ноября, 2025

    CONCLUSIONS AND RELEVANCE: In this randomized clinical trial, prospective use of TEWL as a stopping criterion reduced anaphylaxis rates during OFC in children with peanut allergy, suggesting use of TEWL could make OFC safer and more accessible. Replicating this study in a larger, multicenter population is a reasonable next step. →

    Clinical Trials
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