CONCLUSION: Both JPMR and JPMR combined with cold application are effective short-term interventions for managing migraine without aura. However, the addition of cold application enhances outcomes in the number of attacks. This combined nonpharmacological approach may be considered as an adjunct strategy for migraine management. →

CONCLUSION: Based on the results of the present study, Field massage combined with phototherapy was more effective in increasing the frequency of defecation and reducing the length of hospitalization in infants with hyperbilirubinemia compared to those in the chicory bath group and the control group who received phototherapy only. →

In the primary analysis (32.3-month median follow-up) of the randomized, phase 3 AURIGA study (NCT03901963), daratumumab-lenalidomide (D-R) maintenance significantly improved MRD-negative conversion rates and reduced the risk of disease progression or death by 47% versus R maintenance in anti-CD38 monoclonal antibody-naïve and post-transplant MRD-positive patients with newly diagnosed MM. Here, we present a post hoc… →

CONCLUSIONS: NHFOV appeared superior to NCPAP in reducing the need for intubation when used as a primary respiratory support strategy in extremely preterm infants. Both techniques did not show significant differences in neonatal adverse events. →

CONCLUSIONS: This subgroup analysis of patients who received CYC shows similar rates of remission in the avacopan and prednisone taper groups. Compared with the prednisone taper regimen, the avacopan regimen was associated with a numerically lower relapse rate, greater improvement in eGFR, faster reduction in UACR, lower glucocorticoid-related toxicity and similar overall safety. These results… →

CONCLUSION: Our findings establish a connection between type I interferon signalling, pyrimidine metabolism and uremic toxins in patients with LN and support the evaluation of urine uracil as a potential biomarker of response to anifrolumab. →

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Matt Harrison Clough / Ikon Images In an age where innovation reigns supreme, it’s easy for leaders to believe that a novel business model equals a ticket to success. The logic is appealing: Be the first to offer something new, or something familiar in a new way, and the profits will follow. This idea becomes… →